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T-bet+ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms
Autor:
Eileen Rauch, Timm Amendt, Aleksandra Lopez Krol, Fabian B. Lang, Vincent Linse, Michelle Hohmann, Ann-Christin Keim, Susanne Kreutzer, Kevin Kawengian, Malte Buchholz, Philipp Duschner, Saskia Grauer, Barbara Schnierle, Andreas Ruhl, Ingo Burtscher, Sonja Dehnert, Chege Kuria, Alexandra Kupke, Stephanie Paul, Thomas Liehr, Marcus Lechner, Markus Schnare, Andreas Kaufmann, Magdalena Huber, Thomas H. Winkler, Stefan Bauer, Philipp Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Endogenous retroviruses (ERVs) are an integral part of the mammalian genome. The role of immune control of ERVs in general is poorly defined as is their function as anti-cancer immune targets or drivers of autoimmune disease. Here, we genera
Externí odkaz:
https://doaj.org/article/614f814272ae48b086e1c7fdf428b850
Autor:
Eileen Rauch, Timm Amendt, Aleksandra Lopez Krol, Fabian Lang, Vincent Linse, Michelle Hohmann, Ann-Christin Keim, Susanne Kreutzer, Kevin Kawengian, Malte Buchholz, Philipp Duschner, Saskia Grauer, Barbara Schnierle, Andreas Ruhl, Ingo Burtscher, Sonja Dehnert, Stephanie Paul, Markus Schnare, Andreas Kaufmann, Thomas Winkler, Magdalena Huber, Stefan Bauer, Philipp Yu
Endogenous retroviruses (ERVs) are an integral part of the mammalian genome. The role of immune control of ERVs in general is poorly defined as is their role as anti-cancer immune targets or drivers of autoimmune disease. Here, we generated mouse-str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5461eb22ad2fae2863bc41d8bcbdabc5
https://doi.org/10.21203/rs.3.rs-2666493/v1
https://doi.org/10.21203/rs.3.rs-2666493/v1