Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eileen Puklin-Faucher"'
Publikováno v:
Journal of Cell Science. 122:179-186
Cells govern tissue shape by exerting highly regulated forces at sites of matrix adhesion. As the major force-bearing adhesion-receptor protein, integrins have a central role in how cells sense and respond to the mechanics of their surroundings. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0512d3ec6efea9db5b023df35a0111
https://doi.org/10.1242/jcs.042127
https://doi.org/10.1242/jcs.042127
Publikováno v:
The Journal of Cell Biology
How the integrin head transitions to the high-affinity conformation is debated. Although experiments link activation with the opening of the hinge angle between the betaA and hybrid domains in the ligand-binding headpiece, this hinge is closed in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac6bc69cb2a23cd165e5e9f0680e71d
http://europepmc.org/articles/PMC2064575
http://europepmc.org/articles/PMC2064575
Autor:
Armando del Rio, Nils C. Gauthier, Eileen Puklin-Faucher, Pere Roca-Cusachs, Michael P. Sheetz, Nicolas Biais
Publikováno v:
Proceedings of the National Academy of Sciences. 110
Focal adhesions are mechanosensitive elements that enable mechanical communication between cells and the extracellular matrix. Here, we demonstrate a major mechanosensitive pathway in which α-actinin triggers adhesion maturation by linking integrins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62a075fc1ae31862bbe05e1bf3f1090
https://doi.org/10.1073/pnas.1220723110
https://doi.org/10.1073/pnas.1220723110
Autor:
Eileen Puklin-Faucher, Viola Vogel
Publikováno v:
The Journal of biological chemistry. 284(52)
Integrins form mechanical links between the extracellular matrix and the cytoskeleton. Although integrin activation is known to be regulated by an allosteric conformational change, which can be induced from the extracellular or intracellular end of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dbe66fd3ebaa24feac4e7d9cffadae
https://pubmed.ncbi.nlm.nih.gov/19762919
https://pubmed.ncbi.nlm.nih.gov/19762919
Publikováno v:
Journal of the American Chemical Society. 125(48)
A microscope was constructed for imaging circular dichroism of heterogeneous anisotropic media. To avoid linear biases that are common with electronic circular polarization modulation, we chose a retrogressive solution: mechanical light modulation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812fe7654dbd7d1be184e6432f6c84fa
https://pubmed.ncbi.nlm.nih.gov/14640658
https://pubmed.ncbi.nlm.nih.gov/14640658