Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eileen Pagán-Ramos"'
Autor:
Michele Trucksis, Eileen Pagán-Ramos, Christopher L. Pritchett, Renate Reimschuessel, Sharon Master, Vojo Deretic, Graham S. Timmins
Publikováno v:
Journal of Bacteriology. 188:2674-2680
The majority of slow-growing mycobacteria have a functional oxyR , the central regulator of the bacterial oxidative stress response. In contrast, this gene has been inactivated during the evolution of Mycobacterium tuberculosis . Here we inactivated
Publikováno v:
Journal of Bacteriology. 180:4856-4864
Oxidative stress response in pathogenic mycobacteria is believed to be of significance for host-pathogen interactions at various stages of infection. It also plays a role in determining the intrinsic susceptibility to isoniazid in mycobacterial speci
Publikováno v:
Scopus-Elsevier
Mycobacterium tuberculosis is a natural mutant in oxyR, a close homolog of the central regulator of peroxide stress response in enteric bacteria. Inactivation of oxyR is specific for M. tuberculosis and other members of the M. tuberculosis complex. T
Publikováno v:
Nucleic Acids Research. 22:200-207
Phylogenetic studies of yeast nuclear RNase P RNA genes have shown a striking conservation of secondary structure for the Saccharomyces and Schizosaccharomyces RNase P RNAs, yet much of the primary sequence and many substructures vary among the RNAs
Publikováno v:
Trends in microbiology. 5(9)
The loss of the putative regulator oxyR and the associated dysfunction of oxidative stress response in Mycobacterium tuberculosis may have coincided with, or directly participated in, the evolution of this microorganism into the potent contemporary h
Publikováno v:
Nucleic acids research. 24(16)
RNase P is a ribonucleoprotein endoribonuclease responsible for the 5' maturation of precursor tRNAs in all organisms. While analyzing mutations in conserved positions of the yeast nuclear RNase P RNA subunit, significant accumulation of an aberrant
Publisher Summary Over the past decade, ribonucleic acids (RNAs) have gained recognition as the catalysts for an increasing number of biochemical reactions. This chapter discusses the structures and functions of eukaryotic nuclear ribonuclease P (RNa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d12b962704a115f48935004230c9accf
https://doi.org/10.1016/s0079-6603(08)60190-7
https://doi.org/10.1016/s0079-6603(08)60190-7
Publikováno v:
Molecular biology reports. 22(2-3)
Eukaryotic ribonuclease P (RNase P) enzymes require both RNA and protein subunits for activity in vivo and in vitro. We have undertaken an analysis of the complex RNA subunit of the nuclear holoenzyme in an effort to understand its structure and its
Autor:
Laura E. Via, M. McFalone, Rutilio A. Fratti, Vojo Deretic, Dusanka Deretic, Eileen Pagán-Ramos
Publikováno v:
Scopus-Elsevier
One of the major mechanisms permitting intracellular pathogens to parasitize macrophages is their ability to alter maturation of the phagosome or affect its physical integrity. These processes are opposed by the host innate and adaptive immune defens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0456229d019e9f648beabf62a684fa9
http://www.scopus.com/inward/record.url?eid=2-s2.0-2642649500&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-2642649500&partnerID=MN8TOARS