Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Eileen M. McGowan"'
Autor:
Prangwan Pateetin, Gyorgy Hutvagner, Matthew P. Padula, Eileen M. McGowan, Viroj Boonyaratanakornkit
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-11 (2021)
Measurement(s) progesterone receptor • isoform Technology Type(s) affinity purification method • stable isotope labeling by amino acids in cell culture Factor Type(s) progestin presence • biological replicate Machine-accessible metadata file de
Externí odkaz:
https://doaj.org/article/1692d87f0e024356a048393f61a7bf02
Publikováno v:
BMC Medical Genomics, Vol 11, Iss S6, Pp 73-85 (2018)
Abstract Background Gene expression-based profiling has been used to identify biomarkers for different breast cancer subtypes. However, this technique has many limitations. IsomiRs are isoforms of miRNAs that have critical roles in many biological pr
Externí odkaz:
https://doaj.org/article/88d9c501b72c4c5890e27636fb4cf870
Autor:
Khushwant S. Bhullar, Naiara Orrego Lagarón, Eileen M. McGowan, Indu Parmar, Amitabh Jha, Basil P. Hubbard, H. P. Vasantha Rupasinghe
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-20 (2018)
Abstract The human genome encodes 538 protein kinases that transfer a γ-phosphate group from ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with human cancer initiation and progression. The recent development of
Externí odkaz:
https://doaj.org/article/bffb64b2f11e4eb1be424976b636f3cf
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implicated in the dev
Externí odkaz:
https://doaj.org/article/e66e0438c073488981f1d22adb2c096f
Autor:
Prangwan Pateetin, Gyorgy Hutvagner, Sarah Bajan, Matthew P. Padula, Eileen M. McGowan, Viroj Boonyaratanakornkit
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/bcf32ca643d3487782cc3a3e32838a68
Autor:
Hongjie Chen, Nahal Haddadi, Xiaofeng Zhu, Diana Hatoum, Size Chen, Najah T. Nassif, Yiguang Lin, Eileen M. McGowan
Publikováno v:
Journal of oncology. 2022
Introduction: Overexpression of sphingosine kinase 1 (SphK1) is casually associated with many types of cancer and inhibitors of SphK1 sensitize tumors to chemotherapy. SphK1 is expressed as two major isoforms, SphK1a and SphK1b. To date, no informati
Autor:
Yan Chen, Yiguang Lin, Xianqin Qu, Baoguo Sun, Zexiong Chen, Yue Li, Hongjie Chen, Yingzi Wu, Eileen M. McGowan
Publikováno v:
Translational Metabolic Syndrome Research. 3:25-28
In recent decades, a classic recipe in traditional Chinese medicine, Guilu erxian jiao (GEJ), has been used in the prevention and treatment of myelosuppression following cancer chemotherapy. However, the safety and efficacy of GEJ has not been studie
Publikováno v:
Cancers, Vol 14, Iss 535, p 535 (2022)
Incidence of gastrointestinal (GI) cancers is increasing, and late-stage diagnosis makes these cancers difficult to treat. Chronic and low-grade inflammation are recognized risks for most GI cancers. The GI mucosal immune system maintains healthy hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a17c795c9bc978308922f663e8c733
https://hdl.handle.net/10453/165958
https://hdl.handle.net/10453/165958
Autor:
Viroj, Boonyaratanakornkit, Eileen M, McGowan, Diana C, Márquez-Garbán, L P, Burton, Nalo, Hamilton, Prangwan, Pateetin, Richard J, Pietras
Publikováno v:
Advances in experimental medicine and biology. 1329
The tumor microenvironment (TME) is a complex infrastructure composed of stromal, epithelial, and immune cells embedded in a vasculature ECM. The microenvironment surrounding mammary epithelium plays a critical role during the development and differe
Autor:
Glena, Travis, Nahal, Haddadi, Ann M, Simpson, Deborah J, Marsh, Eileen M, McGowan, Najah T, Nassif
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2324
PTENP1 is a processed pseudogene of the tumour suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN). It functions posttranscriptionally to regulate PTEN by acting as a sponge for microRNAs that target PTEN. PTENP1 therefore funct