Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Eileen M. McGowan"'
Autor:
Prangwan Pateetin, Gyorgy Hutvagner, Matthew P. Padula, Eileen M. McGowan, Viroj Boonyaratanakornkit
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-11 (2021)
Measurement(s) progesterone receptor • isoform Technology Type(s) affinity purification method • stable isotope labeling by amino acids in cell culture Factor Type(s) progestin presence • biological replicate Machine-accessible metadata file de
Externí odkaz:
https://doaj.org/article/1692d87f0e024356a048393f61a7bf02
Publikováno v:
BMC Medical Genomics, Vol 11, Iss S6, Pp 73-85 (2018)
Abstract Background Gene expression-based profiling has been used to identify biomarkers for different breast cancer subtypes. However, this technique has many limitations. IsomiRs are isoforms of miRNAs that have critical roles in many biological pr
Externí odkaz:
https://doaj.org/article/88d9c501b72c4c5890e27636fb4cf870
Autor:
Khushwant S. Bhullar, Naiara Orrego Lagarón, Eileen M. McGowan, Indu Parmar, Amitabh Jha, Basil P. Hubbard, H. P. Vasantha Rupasinghe
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-20 (2018)
Abstract The human genome encodes 538 protein kinases that transfer a γ-phosphate group from ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with human cancer initiation and progression. The recent development of
Externí odkaz:
https://doaj.org/article/bffb64b2f11e4eb1be424976b636f3cf
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implicated in the dev
Externí odkaz:
https://doaj.org/article/e66e0438c073488981f1d22adb2c096f
Autor:
Prangwan Pateetin, Gyorgy Hutvagner, Sarah Bajan, Matthew P. Padula, Eileen M. McGowan, Viroj Boonyaratanakornkit
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/bcf32ca643d3487782cc3a3e32838a68
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 9, p 1891 (2017)
Sphingosine kinase (SphK) is a lipid enzyme that maintains cellular lipid homeostasis. Two SphK isozymes, SphK1 and SphK2, are expressed from different chromosomes and several variant isoforms are expressed from each of the isozymes, allowing for the
Externí odkaz:
https://doaj.org/article/7b20b403bbe24e5bbf1220b7d0e17342
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169925 (2017)
The annexin family and S100A associated proteins are important regulators of diverse calcium-dependent cellular processes including cell division, growth regulation and apoptosis. Dysfunction of individual annexin and S100A proteins is associated wit
Externí odkaz:
https://doaj.org/article/956448d80ce44ba4bcf485351f1577a7
Autor:
Hongjie Chen, Nahal Haddadi, Xiaofeng Zhu, Diana Hatoum, Size Chen, Najah T. Nassif, Yiguang Lin, Eileen M. McGowan
Publikováno v:
Journal of oncology. 2022
Introduction: Overexpression of sphingosine kinase 1 (SphK1) is casually associated with many types of cancer and inhibitors of SphK1 sensitize tumors to chemotherapy. SphK1 is expressed as two major isoforms, SphK1a and SphK1b. To date, no informati
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159151 (2016)
Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine important in normal and pathological biological processes. Newly synthesized pro-TNF-α is expressed on the plasma membrane and cleaved to release soluble TNF-α protein: both are bi
Externí odkaz:
https://doaj.org/article/2ef6a14ef75344e8b9bbeee8d77c416d
Autor:
Yan Chen, Yiguang Lin, Xianqin Qu, Baoguo Sun, Zexiong Chen, Yue Li, Hongjie Chen, Yingzi Wu, Eileen M. McGowan
Publikováno v:
Translational Metabolic Syndrome Research. 3:25-28
In recent decades, a classic recipe in traditional Chinese medicine, Guilu erxian jiao (GEJ), has been used in the prevention and treatment of myelosuppression following cancer chemotherapy. However, the safety and efficacy of GEJ has not been studie