Zobrazeno 1 - 10
of 927
pro vyhledávání: '"Eileen M O'Reilly"'
Autor:
Ghassan K. Abou-Alfa, Tim Meyer, Richard Kinh Gian Do, Sarina A. Piha-Paul, Joseph S. Light, Scott Sherrin, Amin Yaqubie, Alison Clemens O’Neill, James J. Harding, Raed Al-Rajabi, Crystal S. Denlinger, Pablo Cano, Albert S. Cornelius, Eileen M. O'Reilly, Daniel DiPrimeo, Lisa D. Eli, John D. Gordan, David B. Solit
Publikováno v:
Liver Cancer, Pp 1-10 (2024)
Introduction: Fibrolamellar carcinoma (FLC) displays upregulation of several oncogenes, including HER2, and multiple immune-suppressive mechanisms. We investigated the efficacy and safety of the pan-HER tyrosine kinase inhibitor neratinib as monother
Externí odkaz:
https://doaj.org/article/060277f2d7054affa161c9c60698ca95
Autor:
Janet A. Alvarez, Qian Shi, Arvind Dasari, Julio Garcia-Aguilar, Hanna Sanoff, Thomas J. George, Theodore Hong, Greg Yothers, Philip Philip, Garth Nelson, Tareq Al Baghdadi, Olatunji B. Alese, Wini Zambare, Dana Omer, Floris S. Verheij, Aron Bercz, Min Jung Kim, James Buckley, Hannah Williams, Manju George, Reese Garcia, Phuong Gallagher, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Jamie Crawley, Ardaman Shergill, Natally Horvat, Paul B. Romesser, William Hall, J. Joshua Smith
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Recent data have demonstrated that in locally advanced rectal cancer (LARC), a total neoadjuvant therapy (TNT) approach improves compliance with chemotherapy and increases rates of tumor response compared to neoadjuvant chemoradia
Externí odkaz:
https://doaj.org/article/f410276cdec24b44bc5dee5b6d527eee
Autor:
Jacob E. Till, Lee McDaniel, Changgee Chang, Qi Long, Shannon M. Pfeiffer, Jaclyn P. Lyman, Lacey J. Padrón, Deena M. Maurer, Jia Xin Yu, Christine N. Spencer, Pier Federico Gherardini, Diane M. Da Silva, Theresa M. LaVallee, Charles Abbott, Richard O. Chen, Sean M. Boyle, Neha Bhagwat, Samuele Cannas, Hersh Sagreiya, Wenrui Li, Stephanie S. Yee, Aseel Abdalla, Zhuoyang Wang, Melinda Yin, Dominique Ballinger, Paul Wissel, Jennifer Eads, Thomas Karasic, Charles Schneider, Peter O’Dwyer, Ursina Teitelbaum, Kim A. Reiss, Osama E. Rahma, George A. Fisher, Andrew H. Ko, Zev A. Wainberg, Robert A. Wolff, Eileen M. O’Reilly, Mark H. O’Hara, Christopher R. Cabanski, Robert H. Vonderheide, Erica L. Carpenter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract While high circulating tumor DNA (ctDNA) levels are associated with poor survival for multiple cancers, variant-specific differences in the association of ctDNA levels and survival have not been examined. Here we investigate KRAS ctDNA (ctKR
Externí odkaz:
https://doaj.org/article/4f9cd688d606493b979047418e6f71a0
Autor:
Kathryn E. Hitchcock, Eric D. Miller, Qian Shi, Jesse G. Dixon, Sepideh Gholami, Sarah B. White, Christina Wu, Christopher C. Goulet, Manju George, Kyung-Wook Jee, Chadwick L. Wright, Rona Yaeger, Ardaman Shergill, Theodore S. Hong, Thomas J. George, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Paul B. Romesser
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background For patients with liver-confined metastatic colorectal cancer (mCRC), local therapy of isolated metastases has been associated with long-term progression-free and overall survival (OS). However, for patients with more advanced mCR
Externí odkaz:
https://doaj.org/article/a12441bd0abc4f59b450ff5143ff3561
Autor:
Padmanee Sharma, Asim Amin, Dung T Le, Michael A Morse, Marina Tschaika, Matthew H Taylor, Margaret Callahan, Katriina J Peltola, Frederic J Kaye, Eileen M O'Reilly, Stephanie Meadows Shropshire, Shaun O'Brien
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)
Background Pancreatic cancer is one of the deadliest cancer types and represents a major unmet medical need. CheckMate 032 investigated safety and efficacy of nivolumab monotherapy and nivolumab plus ipilimumab with/without cobimetinib in advanced/me
Externí odkaz:
https://doaj.org/article/45a8cb7600f34aa197804f7caa0fc19c
Autor:
Edward Christopher Dee, Victor C. Ng, Eileen M. O’Reilly, Alice C. Wei, Stephanie M. Lobaugh, Anna M. Varghese, Melissa Zinovoy, Paul B. Romesser, Abraham J. Wu, Carla Hajj, John J. Cuaron, Danny N. Khalil, Wungki Park, Kenneth H. Yu, Zhigang Zhang, Jeffrey A. Drebin, William R. Jarnagin, Christopher H. Crane, Marsha Reyngold
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 9, p 2631 (2024)
Introduction: The rate of isolated locoregional recurrence after surgery for pancreatic adenocarcinoma (PDAC) approaches 25%. Ablative radiation therapy (A-RT) has improved outcomes for locally advanced disease in the primary setting. We sought to ev
Externí odkaz:
https://doaj.org/article/e5daf592d8314f32af09518b56a1863b
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9496-9505 (2023)
Abstract Background Subgroup analyses of the NAPOLI‐1 study identified that among patients who were irinotecan naïve prior to entering the clinical trial, a survival benefit was observed between the study arm and control arm. This treatment benefi
Externí odkaz:
https://doaj.org/article/0f119c35950048d1824f7cadc9131a94
Autor:
Fergus Keane, Raazi Bajwa, Pier Selenica, Wungki Park, Michael H. Roehrl, Jorge S. Reis-Filho, Diana Mandelker, Eileen M. O’Reilly
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-8 (2023)
Abstract Poorly differentiated pancreatic neuroendocrine tumors (PDNEC), are a subtype of pancreatic cancer encompassing both small cell and large cell neuroendocrine carcinoma subtypes, and are characterized as distinct in terms of biology and progn
Externí odkaz:
https://doaj.org/article/190db58c7ab44bb79fe3e0deef0cefb6
Autor:
Robert H Vonderheide, Andrew H Ko, Danny Khalil, Oliver Rosen, Robert A Wolff, James Francis, Samantha Bucktrout, Christopher R Cabanski, Silvia Boffo, Zev A Wainberg, Samik Upadhaya, Eileen M O’Reilly, Mark H O’Hara, George Fisher, Jamie Arnott, Ana Rosa Saez-Ibanez, Jay Campbell, Ute Dugan, Jill O’Donnell-Tormey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b601525223344c068784d6ee00423943
Autor:
James Harding, Allison Richards, Dae Won Kim, Wungki Park, Kevin Soares, Danny Khalil, Olca Basturk, Mark Donoghue, William Jarnagin, Darren Cowzer, Ghassan Abou-Alfa, Fergus Keane, Hulya Sahin Ozkan, Vasilisa Rudneva, Bruno A Costa, Zeyneb Tarcan, Eileen M O’Reilly
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/20f72e96366d4b2f86a1fdb822d30632