Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Eileen M Burd"'
Autor:
Pratyusha Mandal, John D Lyons, Eileen M Burd, Michael Koval, Edward S Mocarski, Craig M Coopersmith
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0246270 (2021)
During infectious disease, pathogen load drives inflammation and immune response that together contribute to tissue injury often resulting in organ dysfunction. Pulmonary failure in SARS-CoV2-infected hospitalized COVID-19 patients is one such promin
Externí odkaz:
https://doaj.org/article/a29f93cb0fe84b6992d31c454a7c8bf4
Publikováno v:
The Lancet Microbe, Vol 1, Iss 8, Pp e314-e315 (2020)
Externí odkaz:
https://doaj.org/article/77a10c1835a04a29b2e54a22bf2ce6da
Autor:
Benyam P Yoseph, Elise Breed, Christian E Overgaard, Christina J Ward, Zhe Liang, Maylene E Wagener, Daniel R Lexcen, Elizabeth R Lusczek, Greg J Beilman, Eileen M Burd, Alton B Farris, David M Guidot, Michael Koval, Mandy L Ford, Craig M Coopersmith
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239568 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0062792.].
Externí odkaz:
https://doaj.org/article/26818326965f4f418f4dc66d627bc330
Autor:
John D Lyons, Rohit Mittal, Katherine T Fay, Ching-Wen Chen, Zhe Liang, Lindsay M Margoles, Eileen M Burd, Alton B Farris, Mandy L Ford, Craig M Coopersmith
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149069 (2016)
BACKGROUND:Mortality is significantly higher in septic patients with cancer than in septic patients without a history of cancer. We have previously described a model of pancreatic cancer followed by sepsis from Pseudomonas aeruginosa pneumonia in whi
Externí odkaz:
https://doaj.org/article/36301c62943248e0b1c0117ea1c69702
Autor:
Rohit Mittal, Maylene Wagener, Elise R Breed, Zhe Liang, Benyam P Yoseph, Eileen M Burd, Alton B Farris, Craig M Coopersmith, Mandy L Ford
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e93523 (2014)
While much of cancer immunology research has focused on anti-tumor immunity both systemically and within the tumor microenvironment, little is known about the impact of pre-existing malignancy on pathogen-specific immune responses. Here, we sought to
Externí odkaz:
https://doaj.org/article/31e83b4735fe437e86aaef097708f8e5
Autor:
Zhe Liang, Yan Xie, Jessica A Dominguez, Elise R Breed, Benyam P Yoseph, Eileen M Burd, Alton B Farris, Nicholas O Davidson, Craig M Coopersmith
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101828 (2014)
BACKGROUND:Mice with conditional, intestine-specific deletion of microsomal triglyceride transfer protein (Mttp-IKO) exhibit a complete block in chylomicron assembly together with lipid malabsorption. Young (8-10 week) Mttp-IKO mice have improved sur
Externí odkaz:
https://doaj.org/article/170b8c7eecb14a639da0e55dd7d2c2fb
Autor:
Benyam P Yoseph, Elise Breed, Christian E Overgaard, Christina J Ward, Zhe Liang, Maylene E Wagener, Daniel R Lexcen, Elizabeth R Lusczek, Greg J Beilman, Eileen M Burd, Alton B Farris, David M Guidot, Michael Koval, Mandy L Ford, Craig M Coopersmith
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62792 (2013)
Patients admitted to the intensive care unit with alcohol use disorders have increased morbidity and mortality. The purpose of this study was to determine how chronic alcohol ingestion alters the host response to sepsis in mice.Mice were randomized t
Externí odkaz:
https://doaj.org/article/70c3e2f167c042e783e930a4112e3e26
Autor:
Jessica A Dominguez, Yan Xie, W Michael Dunne, Benyam P Yoseph, Eileen M Burd, Craig M Coopersmith, Nicholas O Davidson
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49159 (2012)
BackgroundThe small intestine plays a crucial role in the pathophysiology of sepsis and has been referred to as the "motor" of the systemic inflammatory response. One proposed mechanism is that toxic gut-derived lipid factors, transported in mesenter
Externí odkaz:
https://doaj.org/article/b633ef9ab9164c3fad865c10a6aed4bb
Autor:
Jerome C. Anyalebechi, Yini Sun, Carolyn Davis, Maylene E. Wagener, Zhe Liang, Eileen M. Burd, Craig M. Coopersmith, Mandy L. Ford
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionA hallmark of T cell dysregulation during sepsis is the downregulation of costimulatory molecules. CD28 is one of T cell costimulatory molecules significantly altered on memory T cells during sepsis. We recently showed that treatment with
Externí odkaz:
https://doaj.org/article/429754ade8b144558594280f7c10d7ec
Autor:
Nathan J. Klingensmith, Katherine T. Fay, David A. Swift, Julia M.R. Bazzano, John D. Lyons, Ching-wen Chen, Mei Meng, Kimberly M. Ramonell, Zhe Liang, Eileen M. Burd, Charles A. Parkos, Mandy L. Ford, Craig M. Coopersmith
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Expression of the tight junction–associated protein junctional adhesion molecule-A (JAM-A) is increased in sepsis, although the significance of this is unknown. Here, we show that septic JAM-A –/– mice have increased gut permeability, yet parad
Externí odkaz:
https://doaj.org/article/fbfc530dda6d4b10a3967d7271e7af69