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Autor:
Eileen Kisilis, Ozgur Oktem, Brij B. Saxena, Lei Zhu, Premila Rathnam, Meirong Hao, Arkadiy Bomshteyn, Meena Katdare
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:6349-6358
Betulonic acid, derived from betulinol, a pentacyclic styrene, has shown a highly specific anti-prostate cancer activity in in vitro cell cultures. However, due to the lack of solubility of betulonic acid in aqueous medium, its potent anti-cancer act