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Autor:
Eileen C Helzner, Sheldon H. Preskorn, Christine J Guico-Pabia, Jeffrey Paul, Alice I. Nichols, Albena Patroneva
Publikováno v:
Journal of Psychiatric Practice. 14:368-378
BACKGROUND The cytochrome P450 2D6 (CYP2D6) enzyme is responsible for metabolizing approximately 25% of pharmaceutical agents. Individuals with impaired CYP2D6 metabolism and those concomitantly receiving agents that inhibit CYP2D6 can have variation