Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Eileen A, McLaughlin"'
Autor:
Nicole A. Siddall, Franca Casagranda, Timothy M. Johanson, Nicole Dominado, James Heaney, Jessie M. Sutherland, Eileen A. McLaughlin, Gary R. Hime
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract The Drosophila ovary is regenerated from germline and somatic stem cell populations that have provided fundamental conceptual understanding on how adult stem cells are regulated within their niches. Recent ovarian transcriptomic studies have
Externí odkaz:
https://doaj.org/article/6acfb8dca3684d6ea54482be0bd08dc7
Autor:
Karthika Radhakrishnan, Michael Luu, Josie Iaria, Jessie M. Sutherland, Eileen A. McLaughlin, Hong-Jian Zhu, Kate L. Loveland
Publikováno v:
Cells, Vol 12, Iss 7, p 1000 (2023)
Testicular germ cell tumours (TGCTs) are the most common malignancy in young men. Originating from foetal testicular germ cells that fail to differentiate correctly, TGCTs appear after puberty as germ cell neoplasia in situ cells that transform throu
Externí odkaz:
https://doaj.org/article/0975ed647b504f38becfd2b44eff8fed
Publikováno v:
BMC Women's Health, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Previous studies have identified that women living in developed countries have insufficient knowledge of factors which may be contributing to the increasingly high global infertility rates such as maternal age and assisted reprodu
Externí odkaz:
https://doaj.org/article/ecacea8a874247bd9c2668779ddaf942
Autor:
Alexandra E. Peters, Shandelle J. Caban, Eileen A. McLaughlin, Shaun D. Roman, Elizabeth G. Bromfield, Brett Nixon, Jessie M. Sutherland
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Accompanying the precipitous age-related decline in human female fertility is an increase in the proportion of poor-quality oocytes within the ovary. The macroautophagy pathway, an essential protein degradation mechanism responsible for maintaining c
Externí odkaz:
https://doaj.org/article/a239e4e9fea646adbf27c3a9fde278b7
Autor:
Wei Zhou, Simone J. Stanger, Amanda L. Anderson, Ilana R. Bernstein, Geoffry N. De Iuliis, Adam McCluskey, Eileen A. McLaughlin, Matthew D. Dun, Brett Nixon
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-18 (2019)
Abstract Background The mammalian epididymis is responsible for the provision of a highly specialized environment in which spermatozoa acquire functional maturity and are subsequently stored in preparation for ejaculation. Making important contributi
Externí odkaz:
https://doaj.org/article/d95613235ed745e3ab866db445daf2ea
Autor:
Emily R Bryan, Logan K Trim, Pawel Sadowski, Selvam Paramasivan, Jay J Kim, Kyle Gough, Sophia Worley, Toby I Maidment, Alison J Carey, Bettina Mihalas, Eileen A McLaughlin, Kenneth W Beagley
Publikováno v:
Biology of Reproduction. 108:758-777
Chlamydia is the most common bacterial sexually transmitted infection worldwide and it is widely acknowledged that controlling the rampant community transmission of this infection requires vaccine development. In this study, for the first time, we el
Autor:
Bettina P. Mihalas, Geoffry N. De Iuliis, Kate A. Redgrove, Eileen A. McLaughlin, Brett Nixon
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract An increase in intraovarian reactive oxygen species (ROS) has long been implicated in the decline in oocyte quality associated with maternal ageing. Oxidative stress (OS)-induced lipid peroxidation and the consequent generation of highly ele
Externí odkaz:
https://doaj.org/article/79e822f8b2ff4b32b81bf9e9780339cf
Autor:
Lexie Prokopuk, Ellen G Jarred, Rheannon O Blücher, Eileen A McLaughlin, Jessica M Stringer, Patrick S Western
Publikováno v:
Reproduction. 163:167-182
Polycomb repressive complex 2 (PRC2) catalyses the repressive epigenetic modification of histone 3 lysine 27 tri-methylation (H3K27me3) and functions as a key epigenetic regulator during embryonic development. PRC2 is known to regulate the developmen
Autor:
Amanda L. Anderson, Simone J. Stanger, Bettina P. Mihalas, Sonika Tyagi, Janet E. Holt, Eileen A. McLaughlin, Brett Nixon
Publikováno v:
Genomics Data, Vol 6, Iss C, Pp 208-211 (2015)
The mammalian epididymis is a highly specialized region of the male reproductive tract that is lined with a continuous layer of epithelial cells that display a remarkable level of regionalized secretory and absorptive activity. The luminal environmen
Externí odkaz:
https://doaj.org/article/fe1911a1fe1e487999289fcdf63f6bc5
Autor:
Shaghayegh Saeidi, Farnaz Shapouri, Robb U de Iongh, Franca Casagranda, Jessie M Sutherland, Patrick S Western, Eileen A McLaughlin, Mary Familari, Gary R Hime
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190925 (2018)
ESRP1 regulates alternative splicing, producing multiple transcripts from its target genes in epithelial tissues. It is upregulated during mesenchymal to epithelial transition associated with reprogramming of fibroblasts to iPS cells and has been lin
Externí odkaz:
https://doaj.org/article/44cde7960a234885be9fcc2e4cf31801