Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eiko Namba"'
Autor:
Akane Tokumitsu, Tetsufumi Koga, Tamura Akihiro, Mizuka Yokoyama, Toshio Takatsu, Harumi Inoue, Kouki Iida, Keiko Suzuki, Yoko Fujita, Toshiyuki Konosu, Masuda Takeshi, Yuko Yamamoto, Chika Sugihara, Yoshiko Kagoshima, Eiko Namba
Publikováno v:
The Journal of Antibiotics. 72:956-969
Novel muraminomicin derivatives with antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) were synthesized by esterification of the hydroxy group on the diazepanone ring of muraminomicin Z1. Compound 1b (DS14450354) posse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3440786b5ada38acdc89f436650ef43b
https://doi.org/10.1038/s41429-019-0235-3
https://doi.org/10.1038/s41429-019-0235-3
Publikováno v:
Journal of Medical Microbiology. 61:1280-1285
PyrG (CTP synthase) catalyses the conversion of UTP to CTP, an essential step in the pyrimidine metabolic pathway in a variety of bacteria, including those causing community-acquired respiratory tract infections (RTIs). In this study, a luminescence-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f76c6f122d3406ada16fe98bf21432
https://doi.org/10.1099/jmm.0.046052-0
https://doi.org/10.1099/jmm.0.046052-0
Autor:
Ryotaku Inoue, Reina Kaneko, Tsuyoshi Nakamura, Hiroshi Yuita, Tetsufumi Koga, Eiko Namba, Hatsumi Nasu, Takahide Nishi, Takashi Kagari, Yukiko Sekiguchi, Yumi Kawase, Kazuhiko Tamaki, Shintaro Nakayama, Keiko Oguchi-Oshima, Takaichi Shimozato, Noriko Masubuchi, Yumiko Mizuno, Masayoshi Asano, Takahiro Yamaguchi, Wataru Tomisato, Futoshi Nara, Hiromi Doi-Komuro
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3083-3088
We have previously disclosed 1,2,4-oxadiazole derivative 3 as a potent S1P3-sparing S1P1 agonist. Although compound 3 exhibits potent and manageable immunosuppressive efficacy in various in vivo models, recent studies have revealed that its 1,2,4-oxa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dee7d6079550f2c98197e1e96700deda
https://doi.org/10.1016/j.bmcl.2012.03.067
https://doi.org/10.1016/j.bmcl.2012.03.067
Publikováno v:
The Japanese journal of antibiotics. 66(5)
We evaluated the in vitro activity of sitafloxacin against Japanese clinical isolates of Streptococcus pyogenes by broth microdilution susceptibility testing and time-kill studies to elucidate its eradication potential against S. pyogenes. One hundre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12e1c7ad6111a1e1fac4413568b7d6de
https://pubmed.ncbi.nlm.nih.gov/24527519
https://pubmed.ncbi.nlm.nih.gov/24527519
Publikováno v:
FEMS microbiology letters. 330(2)
PyrH is a member of the UMP kinase family that catalyses the conversion of UMP to UDP, an essential step in the pyrimidine metabolic pathway in a variety of bacteria including those causing community-acquired respiratory tract infections (RTIs). In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fb2c7133f1a368f55fbf859a0b1c8c
https://pubmed.ncbi.nlm.nih.gov/22428584
https://pubmed.ncbi.nlm.nih.gov/22428584
Autor:
Masayoshi, Asano, Tsuyoshi, Nakamura, Yukiko, Sekiguchi, Yumiko, Mizuno, Takahiro, Yamaguchi, Kazuhiko, Tamaki, Takaichi, Shimozato, Hiromi, Doi-Komuro, Takashi, Kagari, Wataru, Tomisato, Ryotaku, Inoue, Hiroshi, Yuita, Keiko, Oguchi-Oshima, Reina, Kaneko, Futoshi, Nara, Yumi, Kawase, Noriko, Masubuchi, Shintaro, Nakayama, Tetsufumi, Koga, Eiko, Namba, Hatsumi, Nasu, Takahide, Nishi
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(9)
We have previously disclosed 1,2,4-oxadiazole derivative 3 as a potent S1P(3)-sparing S1P(1) agonist. Although compound 3 exhibits potent and manageable immunosuppressive efficacy in various in vivo models, recent studies have revealed that its 1,2,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a56291337d579236e37838536ce301d7
https://pubmed.ncbi.nlm.nih.gov/22487179
https://pubmed.ncbi.nlm.nih.gov/22487179
Autor:
Masayo Kakuta, Tetsufumi Koga, Naotoshi Yamamura, Mitsutoshi Uemori, Harumi Inoue, Hatsumi Nasu, Chika Sugihara, Yoko Matsushita, Akane Tokumitsu, Kiyoshi Sugihara, Eiko Namba
Tomopenem (formerly CS-023) is a novel carbapenem with broad-spectrum activities against diverse hospital pathogens, including Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA). We examined the in vivo pharmacodynamic char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d889a2327df65f5b9fa3c5f855d60d
https://europepmc.org/articles/PMC2981229/
https://europepmc.org/articles/PMC2981229/
Tomopenem (formerly CS-023), a novel 1β-methylcarbapenem, exhibited high affinity for penicillin-binding protein (PBP) 2 in Staphylococcus aureus , PBP 2 in Escherichia coli , and PBPs 2 and 3 in Pseudomonas aeruginosa , which are considered major l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469c74552a170a769dd384ace20d66c2
https://europepmc.org/articles/PMC2650550/
https://europepmc.org/articles/PMC2650550/