Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Eiko N Minakawa"'
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287065 (2023)
Generating non-human primate models of human diseases is important for the development of therapeutic strategies especially for neurodegenerative diseases. The common marmoset has attracted attention as a new experimental animal model, and many trans
Externí odkaz:
https://doaj.org/article/d10a4dabd31145ebbf42d775331164df
Autor:
Ryusuke Sakai, Mari Suzuki, Morio Ueyama, Toshihide Takeuchi, Eiko N Minakawa, Hideki Hayakawa, Kousuke Baba, Hideki Mochizuki, Yoshitaka Nagai
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218261 (2019)
Parkinson's disease (PD) is one of the most common neurodegenerative diseases, which is characterized by progressive motor dysfunction as well as non-motor symptoms. Pathological and genetic studies have demonstrated that α-synuclein (αSyn) plays k
Externí odkaz:
https://doaj.org/article/aa6d65589d37445a94d92be4b88831f4
Autor:
Eiko N. Minakawa
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease (AD). Both diseases share common clinical and pathological features: the gradual progression of neurological and psychiatric symptoms caused by neu
Externí odkaz:
https://doaj.org/article/24c5ef4dacd9458da7f499a7db915e76
Autor:
Yumi Yamamoto, Katsutoshi Kojima, Daisuke Taura, Masakatsu Sone, Kazuo Washida, Naohiro Egawa, Takayuki Kondo, Eiko N. Minakawa, Kayoko Tsukita, Takako Enami, Hidekazu Tomimoto, Toshiki Mizuno, Raj N. Kalaria, Nobuya Inagaki, Ryosuke Takahashi, Mariko Harada-Shiba, Masafumi Ihara, Haruhisa Inoue
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is one of the most common forms of hereditary cerebral small vessel diseases and is caused by mutations in NOTCH3. Our group has previously
Externí odkaz:
https://doaj.org/article/b9af76ea335a4855af63285e62998857
Autor:
Toshihide Takeuchi, Kazuhiro Maeta, Xin Ding, Yukako Oe, Akiko Takeda, Mana Inoue, Seiichi Nagano, Tsuyoshi Fujihara, Seiji Matsuda, Shinsuke Ishigaki, Kentaro Sahashi, Eiko N. Minakawa, Hideki Mochizuki, Masahiro Neya, Gen Sobue, Yoshitaka Nagai
Publikováno v:
Molecular Therapy - Nucleic Acids. 31:353-366
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1ce721c213d203435a81be1c599fe70
https://doi.org/10.1016/j.omtn.2023.01.006
https://doi.org/10.1016/j.omtn.2023.01.006
Autor:
Mari Suzuki, Masahisa Katsuno, Keiji Wada, Yasuo Takahashi, Hiroshi Yamane, Yoshitaka Nagai, Akiko Takeda, Kei Watase, Hiroaki Adachi, Toshihide Takeuchi, Hiroko Yagihara, Eiko N. Minakawa, Chiyomi Ito, Helena Akiko Popiel, Toshiaki Takahashi, Kentaro Shiraki, Yuko Saito, Hideki Mochizuki, Masayoshi Tada, Yuma Okamoto, Kazuhiro Yamamoto, Daisaku Ozawa, Tatsushi Toda, Gen Sobue, Hiromi Fujita, Osamu Onodera, Yuji Saitoh
Publikováno v:
Brain. 143:1811-1825
The polyglutamine (polyQ) diseases are a group of inherited neurodegenerative diseases that include Huntington’s disease, various spinocerebellar ataxias, spinal and bulbar muscular atrophy, and dentatorubral pallidoluysian atrophy. They are caused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4f73ca15a62ebe41ff1064b654b1cf
https://doi.org/10.1093/brain/awaa115
https://doi.org/10.1093/brain/awaa115
Autor:
Nobuya Inagaki, Masafumi Ihara, Toshiki Mizuno, Masakatsu Sone, Raj N. Kalaria, Yamamoto Yumi, Katsutoshi Kojima, Ryosuke Takahashi, Eiko N. Minakawa, Takako Enami, Hidekazu Tomimoto, Kayoko Tsukita, Kazuo Washida, Haruhisa Inoue, Mariko Harada-Shiba, Daisuke Taura, Naohiro Egawa, Takayuki Kondo
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-12 (2020)
Molecular Brain
Molecular Brain
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is one of the most common forms of hereditary cerebral small vessel diseases and is caused by mutations in NOTCH3. Our group has previously reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53481746bb1e56b84b3b7aca50c3f413
http://link.springer.com/article/10.1186/s13041-020-00573-w
http://link.springer.com/article/10.1186/s13041-020-00573-w
Autor:
Eiko N. Minakawa, Yoshitaka Nagai
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, Vol 15 (2021)
The polyglutamine (polyQ) diseases are a group of inherited neurodegenerative diseases caused by the abnormal expansion of a CAG trinucleotide repeat that are translated into an expanded polyQ stretch in the disease-causative proteins. The expanded p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff2773a9e483fbb67d6087a9282ea3b
https://pubmed.ncbi.nlm.nih.gov/33642983
https://pubmed.ncbi.nlm.nih.gov/33642983
Autor:
Hiroko Yagihara, Hiromi Fujita, Yoshitaka Nagai, Kazushi Maruo, Eiko N. Minakawa, Koyomi Miyazaki, Keiji Wada
Publikováno v:
Neuroscience Letters. 653:362-369
Sleep fragmentation due to intermittent nocturnal arousal resulting in a reduction of total sleep time and sleep efficiency is a common symptom among people with Alzheimer's disease (AD) and elderly people with normal cognitive function. Although epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb457333b4a52550fdeba9fd4e8c8919
https://doi.org/10.1016/j.neulet.2017.05.054
https://doi.org/10.1016/j.neulet.2017.05.054
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 4, p 803 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Sleep disturbance is a common symptom in patients with various neurodegenerative diseases, including Alzheimer’s disease (AD), and it can manifest in the early stages of the disease. Impaired sleep in patients with AD has been attributed to AD path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f663a7acf06477a1d5c5344be328aaf
https://www.mdpi.com/1422-0067/20/4/803
https://www.mdpi.com/1422-0067/20/4/803