Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Eikichi HOSOYA"'
Autor:
Jong-Chol Cyong, Hideki Kawamura, Masaki Aburada, Yasuhiro Komatsu, Hiroaki Kiyohara, Norito Takemoto, Ji-Fu Zhao, Haruki Yamada, Eikichi Hosoya
Publikováno v:
Planta Medica. 58:166-170
The Kampo (Japanese herbal) medicine "Juzen-Taiho-To" (TJ-48), which was prepared by decocting a concoction (formula), contains ten kinds of herbs and has several immunostimulating activities. In order to determine the contribution of each herbal com
Autor:
Yoshio Esumi, Tsutomu Oyama, Yoshitaka Jin, Hiroshi Mitsuhashi, Hiromi Sasaki, Shuichi Takeda, Tetsuyoshi Yokoshima, Masaki Aburada, Hisako Ishikawa, Eikichi Hosoya, Yukinobu Ikeya, Yutaka Matsuzaki, Tamae Matsuzaki
Publikováno v:
Drug Metabolism and Pharmacokinetics. 7:477-494
Autor:
Eikichi Hosoya, Masaki Aburada, Yukinobu Ikeya, Hiroshi Mitsuhashi, Yoshio Esumi, Yoshitaka Jin, Yutaka Matsuzaki, Shuichi Takeda, Tsutomu Oyama, Hiromi Sasaki, Tetsuyoshi Yokoshima, Tamae Matsuzaki, Hisako Ishikawa
Publikováno v:
Drug Metabolism and Pharmacokinetics. 7:519-527
The Metabolism of TJN-101 was studied in rats after oral administration of 3H-TJN-101. 1. At 0.75hr after the oral administration of 3H-TJN-101 (4mg/kg) to fasted rats, 30.0%, 18.1%, and 8.5% of the radioactivity was present in the plasma as unchange
Autor:
Shuichi Takeda, Tetsuyoshi Yokoshima, Hisako Ishikawa, Tamae Matsuzaki, Yoshitaka Jin, Yoshio Esumi, Hiromi Sasaki, Yutaka Matsuzaki, Tsutomu Oyama, Eikichi Hosoya, Masaki Aburada
Publikováno v:
Drug Metabolism and Pharmacokinetics. 7:509-518
Autor:
Haruki Yamada, Hideki Kawamura, Eikichi Hosoya, Norito Takemoto, Hiroaki Kiyohara, Yasuhiro Komatsu
Publikováno v:
Planta Medica. 57:254-259
The acidic polysaccharide fraction (F-5-2) from "Juzen-Taiho-To" (TJ-48), a Kampo (Japanese herbal) medicine prepared by decocting a prescription of 10 kinds of herbs, has potent mitogenic activity. In order to clarify the mitogenic activity, F-5-2 w
Autor:
Yutaka MATSUZAKI, Tamae MATSUZAKI, Hiromasa ONO, Sachiko KOGUCHI, Shuichi TAKEDA, Shigefumi TAKEDA, Shuji FUNO, Masaki ABURADA, Eikichi HOSOYA, Tsutomu OYAMA
Publikováno v:
YAKUGAKU ZASSHI. 111:531-537
The absorption and excretion of gomisin A (TJN-101) in rats whose livers were injured by carbon tetrachloride (CCl4) were investigated. After intravenous administration of TJN-101 at a dose of 5 mg/kg, the terminal elimination half-life was 1.5 h in
Autor:
Mitsutoshi Yuzurihara, Kyoji Sekiguchi, Masaki Aburada, Eikichi Hosoya, Akira Sugimoto, Kyuya Kogure, Kazuhiro Goto, Susumu Iizuka, Atsushi Ishige
Publikováno v:
Brain Research. 534:299-302
The effect of cycloheximide, a protein synthesis inhibitor, on hippocampal selective neuronal death was morphologically studied in rats subjected to 10 min forebrain ischemia using a 4-vessel occlusion model. Neuronal damage in the hippocampal CA1 su
Autor:
Haruki Yamada, Norito Takemoto, Hiroaki Kiyohara, Yasuhiro Komatsu, Hideki Kawamura, Masaki Aburada, Eikichi Hosoya, Jong-Chol Cyong
Publikováno v:
Planta Medica. 56:386-391
"Juzen-Taiho-To" (TJ-48), which is a kampo (Japanese herbal) medicine prepared by decocting a prescription of ten kinds of herbs, has several immunostimulating activities. In order to characterize the active substances for anti-complementary and mito
Autor:
Toshihatsu Kitade, Yoshinobu Odahara, Shoji Shinohara, Takaharu Ikeuchi, Takao Sakai, Kazuhiro Morikawa, Masazumi Minamikawa, Sumie Toyota, Akira Kawachi, Masayoshi Hyodo, Eikichi Hosoya
Publikováno v:
Acupuncture & Electro-Therapeutics Research. 15:121-135
D-phenylalanine (DPA) is known to block the activity of carboxypeptidase, an enzyme which degrades enkephalins, endogenous morphine-like substances. Therefore, it is considered that DPA administered as an inhibiting drug of this degrading enzyme migh
Autor:
Hiromi Sasaki, Eikichi Hosoya, Yutaka Matsuzaki, Sachiko Koguchi, Yukinobu Ikeya, Hiroshi Mitsuhashi, Shuichi Takeda, Tsutomu Oyama, Masaki Aburada, Tamae Matsuzaki
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 111(9)
Gomisin A (TJN-101) is one of the lignan components isolated from Schisandra Fruits and expected to have some efficacies in clinical treatment of hepatitis. The serum concentrations of TJN-101 and Met. B, which was identified as a demethylenated subs