Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Eike Mrosek"'
Autor:
James S. Fitzsimmons, Shawn W. O'Driscoll, Jan C. Schagemann, H. W. Chung, Gregory G. Reinholz, Eike Mrosek
Publikováno v:
Bone & Joint Research
Objectives We sought to determine if a durable bilayer implant composed of trabecular metal with autologous periosteum on top would be suitable to reconstitute large osteochondral defects. This design would allow for secure implant fixation, subseque
Publikováno v:
Operative Orthopädie und Traumatologie. 20:199-207
Arthroskopische Rekonstruktion der Gelenkflache mit resorbierbaren Zelltragern zur Behandlung vollschichtiger Knorpeldefekte und damit zur langfristigen Vermeidung einer Progression der Arthrose. Vollschichtige, bis auf den Knochen reichende Knorpeld
Publikováno v:
Osteoarthritis and Cartilage. 14:171-178
Summary Joint instability was believed to be the main cause of osteoarthritis following non-fracture articular trauma. However, sudden high impact load through articular cartilage onto subchondral bone may also cause osteoarthritic changes. Objective
Publikováno v:
Acta Radiologica. 46:875-880
Purpose: To describe the magnetic resonance imaging (MRI) signs of technically successful osteochondral plug transfer and to correlate the findings with histology using the Mankin score. Material and Methods: The study was done in a prospective anima
Autor:
Andreas, Lahm, Richard, Kasch, Heiko, Spank, Christoph, Erggelet, Jan, Esser, Harry, Merk, Eike, Mrosek
Publikováno v:
Histology and histopathology. 29(11)
Cartilage degeneration of the knee joint is considered to be a largely mechanically driven process. We conducted a microstructural and histomorphometric analysis of subchondral bone samples of intact cartilage and in samples with early and higher- gr
Autor:
Andreas, Lahm, Richard, Kasch, Eike, Mrosek, Heiko, Spank, Christoph, Erggelet, Jan, Esser, Harry, Merk
Publikováno v:
Histology and histopathology. 27(5)
The study was conducted to examine the expression of collagen type I and II in the different cartilage layers in relation to other ECM molecules during the progression of early osteoarthritic degeneration in human articular cartilage (AC). Quantitati
Autor:
James S. Fitzsimmons, Mahrokh Dadsetan, Shawn W. O'Driscoll, Jan C. Schagemann, Gregory G. Reinholz, Michelle E. Casper, Eike Mrosek, Haymo Kurz, James S. Stone, Sun Yu-Long
Publikováno v:
Biomaterials. 31(10)
Previously we demonstrated that chondrocyte ECM synthesis and mitotic activity was dependent on scaffold composition when cultured on uncoated PCL scaffolds (pPCL) or PCL composites containing hyaluronan (PCL/HA), chitosan (PCL/CS), fibrin (PCL/F), o
Autor:
Heiko Spank, Jan Esser, Richard Kasch, Andreas Lahm, Christoph Erggelet, Eike Mrosek, Harry Merk
Publikováno v:
Archives of orthopaedic and trauma surgery. 130(4)
The different cartilage layers vary in synthesis of proteoglycan and of the distinct types of collagen with the predominant collagen Type II with its associated collagens, e.g. types IX and XI, produced by normal chondrocytes. It was demonstrated tha
Publikováno v:
Operative Orthopadie und Traumatologie. 20(3)
Arthroscopic implantation of resorbable, three-dimensional scaffolds for the treatment of full-thickness cartilage defects.Full-thickness cartilage defect mainly in the knee joint.Advanced osteoarthritis, rheumatoid arthritis, avascular osteonecrosis
Autor:
H. W. Chung, Jan C. Schagemann, James S. Fitzsimmons, Shawn W. O'Driscoll, Gregory G. Reinholz, James J. Stone, Eike Mrosek
Publikováno v:
Journal of Biomedical Materials Research Part A.
The aim of this study was to determine the suitability of hybrid scaffolds composed of naturally derived biopolymer gels and macroporous poly-ϵ-caprolactone (PCL) scaffolds for neocartilage formation in vitro. Rabbit articular chondrocytes were seed