Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eike Keßel"'
Autor:
Laura Nimtz, Julia Hartmann, Julia Tigges, Stefan Masjosthusmann, Martin Schmuck, Eike Keßel, Stephan Theiss, Karl Köhrer, Patrick Petzsch, James Adjaye, Claudia Wigmann, Dagmar Wieczorek, Barbara Hildebrandt, Farina Bendt, Ulrike Hübenthal, Gabriele Brockerhoff, Ellen Fritsche
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
Neurotoxicity is mediated by a variety of modes-of-actions leading to disturbance of neuronal function. In order to screen larger numbers of compounds for their neurotoxic potential, in vitro functional neuronal networks (NN) might be helpful tools.
Externí odkaz:
https://doaj.org/article/6ce21a344da041f7ac23989029624edd
Autor:
Kristina Bartmann, Farina Bendt, Arif Dönmez, Daniel Haag, Eike Keßel, Stefan Masjosthusmann, Christopher Noel, Ji Wu, Peng Zhou, Ellen Fritsche
Proper brain development is based on the orchestration of key neurodevelopmental processes, including the formation and function of neural networks. If at least one key neurodevelopmental process is affected by a chemical, an adverse outcome is expec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f49dceb22460d83b6be4d23df085faba
https://doi.org/10.1101/2023.01.12.523741
https://doi.org/10.1101/2023.01.12.523741
Autor:
Jonathan Blum, Stefan Masjosthusmann, Kristina Bartmann, Farina Bendt, Xenia Dolde, Arif Dönmez, Nils Förster, Anna-Katharina Holzer, Ulrike Hübenthal, Hagen Eike Keßel, Sadiye Kilic, Jördis Klose, Melanie Pahl, Lynn-Christin Stürzl, Iris Mangas, Andrea Terron, Kevin M. Crofton, Martin Scholze, Axel Mosig, Marcel Leist, Ellen Fritsche
Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human exposome. However, DNT data from animal studies are available for only a small percentage of manufactured compounds. Test methods with a higher throughput than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04065f0054d0235280408ccf7d7668ba
https://zenodo.org/record/7752644
https://zenodo.org/record/7752644
Autor:
Hagen Eike Keßel, Stefan Masjosthusmann, Kristina Bartmann, Jonathan Blum, Arif Dönmez, Nils Förster, Jördis Klose, Axel Mosig, Melanie Pahl, Marcel Leist, Martin Scholze, Ellen Fritsche
In the field of hazard assessment, Benchmark concentrations (BMC) and their associated uncertainty are of particular interest for regulatory decision making. The BMC estimation consists of various statistical decisions to be made, which depend largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6e108bfa48313822ffb51452e55d5b
https://doi.org/10.1101/2022.10.18.512648
https://doi.org/10.1101/2022.10.18.512648
Autor:
Adrian Covaci, Julia Tigges, Mamta Behl, Marcel Leist, Stefan Masjosthusmann, Hagen Eike Keßel, Lynn-Christin Stürzl, Ulrike Hübenthal, Andrea Rossi, Melanie Pahl, Jördis Klose, Nils Förster, Jonathan Blum, Katharina Koch, Sabine Schneider, Xenia Dolde, Ellen Fritsche, Farina Bendt, Anna-Katharina Holzer, Kristina Bartmann, Selina Woeste
Publikováno v:
Cell biology and toxicology
Due to their neurodevelopmental toxicity, flame retardants (FRs) like polybrominated diphenyl ethers are banned from the market and replaced by alternative FRs, like organophosphorus FRs, that have mostly unknown toxicological profiles. To study thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8478aeae161818bea56354ed8fb441
https://doi.org/10.1007/s10565-021-09603-2
https://doi.org/10.1007/s10565-021-09603-2
Autor:
Nils Förster, Xiaohui Fan, Farina Bendt, Ellen Fritsche, Melanie Pahl, Joshua Butke, Hagen Eike Keßel, Axel Mosig, Ping-Chung Leung, Jördis Klose, Lu Li, Stefan Masjosthusmann
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical CytologyREFERENCES. 101(5)
Neurosphere cultures consisting of primary human neural stem/progenitor cells (hNPC) are used for studying the effects of substances on early neurodevelopmental processes in vitro. Differentiating hNPCs migrate and differentiate into radial glia, neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dae805b9a64e89801614e74228f8691
https://pubmed.ncbi.nlm.nih.gov/34747115
https://pubmed.ncbi.nlm.nih.gov/34747115
Autor:
Ulrike Hübenthal, Dagmar Wieczorek, Ellen Fritsche, Farina Bendt, James Adjaye, Stefan Masjosthusmann, Julia Hartmann, Stephan Theiss, Gabriele Brockerhoff, Julia Tigges, Barbara Hildebrandt, Karl Köhrer, Martin Schmuck, Laura Nimtz, Eike Keßel, Claudia Wigmann, Patrick Petzsch
Publikováno v:
Stem Cell Research, Vol 45, Iss, Pp-(2020)
Neurotoxicity is mediated by a variety of modes-of-actions leading to disturbance of neuronal function. In order to screen larger numbers of compounds for their neurotoxic potential, in vitro functional neuronal networks (NN) might be helpful tools.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696e55d9b9b70e8f693ae196dbf2c519
https://doi.org/10.1016/j.scr.2020.101761
https://doi.org/10.1016/j.scr.2020.101761