Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Eike K. Mahlandt"'
Autor:
Franka H. van der Linden, Eike K. Mahlandt, Janine J. G. Arts, Joep Beumer, Jens Puschhof, Saskia M. A. de Man, Anna O. Chertkova, Bas Ponsioen, Hans Clevers, Jaap D. van Buul, Marten Postma, Theodorus W. J. Gadella, Joachim Goedhart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Currently, genetically encoded calcium indicators are not suitable for direct quantification. Here the authors engineer a fluorescence lifetime imaging calcium biosensor, Turquoise Calcium Fluorescence LIfeTime Sensor (Tq-Ca-FLITS), and measure intra
Externí odkaz:
https://doaj.org/article/28e02e090b82435fa3bc07ed281bc827
Autor:
Janine J. G. Arts, Eike K. Mahlandt, Lilian Schimmel, Max L. B. Grönloh, Sanne van der Niet, Bart J. A. M. Klein, Mar Fernandez-Borja, Daphne van Geemen, Stephan Huveneers, Jos van Rijssel, Joachim Goedhart, Jaap D. van Buul
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
An inflammatory response requires leukocytes to migrate from the circulation across the vascular lining into the tissue to clear the invading pathogen. Whereas a lot of attention is focused on how leukocytes make their way through the endothelial mon
Externí odkaz:
https://doaj.org/article/c305759e1af542afa349976b10539ac8
Autor:
Eike K Mahlandt, Sebastián Palacios Martínez, Janine JG Arts, Simon Tol, Jaap D van Buul, Joachim Goedhart
Publikováno v:
eLife, Vol 12 (2023)
The inner layer of blood vessels consists of endothelial cells, which form the physical barrier between blood and tissue. This vascular barrier is tightly regulated and is defined by cell-cell contacts through adherens and tight junctions. To investi
Externí odkaz:
https://doaj.org/article/6f771142eee24d0bb49875f225b5d7e6
Autor:
Janine JG Arts, Eike K Mahlandt, Max LB Grönloh, Lilian Schimmel, Ivar Noordstra, Emma Gordon, Abraham CI van Steen, Simon Tol, Barbara Walzog, Jos van Rijssel, Martijn A Nolte, Marten Postma, Satya Khuon, John M Heddleston, Eric Wait, Teng Leong Chew, Mark Winter, Eloi Montanez, Joachim Goedhart, Jaap D van Buul
Publikováno v:
eLife, Vol 10 (2021)
Upon inflammation, leukocytes rapidly transmigrate across the endothelium to enter the inflamed tissue. Evidence accumulates that leukocytes use preferred exit sites, alhough it is not yet clear how these hotspots in the endothelium are defined and h
Externí odkaz:
https://doaj.org/article/e8c403c2145749c68b603d43a3547e87
Autor:
Eike K. Mahlandt, Sebastián Palacios Martínez, Janine J. G. Arts, Simon Tol, Jaap D. van Buul, Joachim Goedhart
The inner layer of blood vessels consists of endothelial cells, which form the physical barrier between blood and tissue. This vascular barrier is tightly regulated to allow the passage of essential molecules like oxygen, carbon-dioxide, water, ions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daa703b53329f0defe16f2c5f4ff69f
https://doi.org/10.7554/elife.84364.1
https://doi.org/10.7554/elife.84364.1
Optogenetics is a fast-growing field, that applies light-sensitive proteins to manipulate cellular processes. A popular optogenetics tool is the improved light-induced dimer (iLID). It comprises two components, iLID and SspB, which heterodimerize upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e08615d2e8de744239f53878599ac6
Autor:
Eike K. Mahlandt, Gabriel Kreider-Letterman, Anna O. Chertkova, Rafael Garcia-Mata, Joachim Goedhart
Rac (herein referring to the Rac family) and Cdc42 are Rho GTPases that regulate the formation of lamellipoda and filopodia, and are therefore crucial in processes such as cell migration. Relocation-based biosensors for Rac and Cdc42 have not been ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebb03178f236d89e06942c6b5960844
Autor:
Eike K, Mahlandt, Joachim, Goedhart
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2440
One obvious feature of life is that it is highly dynamic. The dynamics can be captured by movies that are made by acquiring images at regular time intervals, a method that is also known as time-lapse imaging. Looking at movies is a great way to learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d17263b8f3d2dfbd6814fcd1a1514e60
https://pubmed.ncbi.nlm.nih.gov/35218548
https://pubmed.ncbi.nlm.nih.gov/35218548
HI-NESS: a family of genetically encoded DNA labels based on a bacterial nucleoid-associated protein
Autor:
Patrick Voskamp, Daphne E. C. Boer, Monica Varela Alvarez, Martijn S. Luijsterburg, Fatema-Zahra M Rashid, Frédéric Crémazy, Daan J.W. Brocken, Thomas S Shimizu, Joachim Goedhart, Remus T. Dame, Annemarie H. Meijer, Michiel van der Vaart, Eike K. Mahlandt, Anneloes Blok, Bram Henneman
Publikováno v:
Nucleic Acids Research, 50(2). OXFORD UNIV PRESS
Nucleic Acids Research, 50(2). Oxford University Press (OUP)
Nucleic Acids Research, 50(2)
Nucleic Acids Research, 50(2):e10. Oxford University Press
Nucleic Acids Research
Nucleic Acids Research, 50(2). Oxford University Press (OUP)
Nucleic Acids Research, 50(2)
Nucleic Acids Research, 50(2):e10. Oxford University Press
Nucleic Acids Research
The interplay between three-dimensional chromosome organisation and genomic processes such as replication and transcription necessitates in vivo studies of chromosome dynamics. Fluorescent organic dyes are often used for chromosome labelling in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba901b9bbc62518f82a6e59a9e16dd8
http://hdl.handle.net/1887/3563888
http://hdl.handle.net/1887/3563888