Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Eike Gallmeier"'
Autor:
Hanna Elisabeth Schneider, Lisa-Maria Schmitt, Albert Job, Brigitte Lankat-Buttgereit, Thomas Gress, Malte Buchholz, Eike Gallmeier
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 57, Iss , Pp 101038- (2024)
The ATR-CHK1 pathway plays a fundamental role in the DNA damage response and is therefore an attractive target in cancer therapy. The antitumorous effect of ATR inhibitors is at least partly caused by synthetic lethality between ATR and various DNA r
Externí odkaz:
https://doaj.org/article/d9d2994e1d8b40feb85caf545e7e1dad
Autor:
Thomas J. Ettrich, Andreas W. Berger, Lukas Perkhofer, Severin Daum, Alexander König, Andreas Dickhut, Uwe Wittel, Kai Wille, Michael Geissler, Hana Algül, Eike Gallmeier, Jens Atzpodien, Marko Kornmann, Rainer Muche, Nicole Prasnikar, Andrea Tannapfel, Anke Reinacher-Schick, Waldemar Uhl, Thomas Seufferlein
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Even clearly resectable pancreatic cancer still has an unfavorable prognosis. Neoadjuvant or perioperative therapies might improve the prognosis of these patients. Thus, evaluation of perioperative chemotherapy in resectable pancr
Externí odkaz:
https://doaj.org/article/4b8d6fac7cb54c6aaa9dcd06f710f790
Autor:
Albert Job, Lisa-Maria Schmitt, Lisa von Wenserski, Brigitte Lankat-Buttgereit, Thomas M. Gress, Malte Buchholz, Eike Gallmeier
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 11, Pp 1135-1143 (2018)
The phosphoinositide 3-kinase–related kinase ATR is a central regulator of the DNA damage response. Its chemical inhibition eliminates subsets of cancer cells in various tumor types. This effect is caused at least partly by the synthetically lethal
Externí odkaz:
https://doaj.org/article/2b6c7f300e104b399bc8c52c314357dd
Publikováno v:
Case Reports in Oncology, Vol 4, Iss 2, Pp 336-342 (2011)
Choroidal melanoma is an insidious tumor frequently causing late liver metastases which are associated with a poor outcome. Since metastatic liver lesions are potentially resectable with curative intention, tight follow-up schedules after treatment o
Externí odkaz:
https://doaj.org/article/40a807bc4cd04df59f6f7beb0934304d
Publikováno v:
BioTechniques, Vol 37, Iss 4, Pp 598-602 (2004)
Current DNA electrophoretic solutions employ high ionic concentrations and require long electrophoretic run times. Here we demonstrate that high and low molecular weight double-stranded DNA, single-stranded DNA (ssDNA), and RNA can be separated rapid
Externí odkaz:
https://doaj.org/article/2d06c79810da47a9acfea26af788185c
Autor:
Eike Gallmeier, Dominik C Bader, Lydia Kriegl, Sabina Berezowska, Hendrik Seeliger, Burkhard Göke, Thomas Kirchner, Christiane Bruns, Enrico N De Toni
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56760 (2013)
IntroductionAgonistic antibodies targeting TRAIL-receptors 1 and 2 (TRAIL-R1 and TRAIL-R2) are being developed as a novel therapeutic approach in cancer therapy including pancreatic cancer. However, the cellular distribution of these receptors in pri
Externí odkaz:
https://doaj.org/article/e4473de467944c5199b82dfe358e786b
Autor:
Lydia Kriegl, Andreas Jung, David Horst, Antonia Rizzani, Rene Jackstadt, Heiko Hermeking, Eike Gallmeier, Alexander L Gerbes, Thomas Kirchner, Burkhard Göke, Enrico N De Toni
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51654 (2012)
The fact that the receptors for the TNF-related apoptosis inducing ligand (TRAIL) are almost invariably expressed in colorectal cancer (CRC) represents the rationale for the employment of TRAIL-receptors targeting compounds for the therapy of patient
Externí odkaz:
https://doaj.org/article/644ec0a59e654382a5afbf78c9bbca8f
Autor:
Ben Ho Park, Kurtis E. Bachman, Eike Gallmeier, Yuko Konishi, Joseph P. Garay, John P. Gustin, Josh Lauring, Abde M. Abukhdeir, Bedri Karakas, Hiroyuki Konishi
Supplementary Figure Legends 1-4 from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378b59285c9413cbc3fbbdcd3d809707
https://doi.org/10.1158/0008-5472.22367298.v1
https://doi.org/10.1158/0008-5472.22367298.v1
Autor:
Scott E. Kern, Myriam Gorospe, Kotb Abdelmohsen, Geppino Falco, Eric S. Calhoun, David A. Dezentje, Tomas Hucl, Eike Gallmeier, Steven C. Cunningham
Supplementary Figure 1 from Targeted Deletion of MKK4 in Cancer Cells: A Detrimental Phenotype Manifests as Decreased Experimental Metastasis and Suggests a Counterweight to the Evolution of Tumor-Suppressor Loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f52d1eb658db15452998d7217cb83b
https://doi.org/10.1158/0008-5472.22365357.v1
https://doi.org/10.1158/0008-5472.22365357.v1
Autor:
Scott E. Kern, Ralph H. Hruban, Aravinda Chakravarti, Christine A. Iacobuzio-Donahue, Anirban Maitra, Dan E. Arking, Kristen M. West, Eike Gallmeier, Tomas Hucl, Eric S. Calhoun
Recent advances in oligonucleotide arrays and whole-genome complexity reduction data analysis now permit the evaluation of tens of thousands of single-nucleotide polymorphisms simultaneously for a genome-wide analysis of allelic status. Using these a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a89f96962da1caaddbaa78f5230cec
https://doi.org/10.1158/0008-5472.c.6494552
https://doi.org/10.1158/0008-5472.c.6494552