Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Eike D. Schomburg"'
Autor:
Payam Dibaj, Jana Zschüntzsch, Heinz Steffens, Jörg Scheffel, Bettina Göricke, Jochen H Weishaupt, Karim Le Meur, Frank Kirchhoff, Uwe-Karsten Hanisch, Eike D Schomburg, Clemens Neusch
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43963 (2012)
Mutations in SOD1 cause hereditary variants of the fatal motor neuron disease amyotrophic lateral sclerosis (ALS). Pathophysiology of the disease is non-cell-autonomous, with toxicity deriving also from glia. In particular, microglia contribute to di
Externí odkaz:
https://doaj.org/article/2e89c0240a874299be60915d21fe406b
Autor:
Payam Dibaj, Heinz Steffens, Jana Zschüntzsch, Fabien Nadrigny, Eike D Schomburg, Frank Kirchhoff, Clemens Neusch
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17910 (2011)
Mutations in the enzyme superoxide dismutase-1 (SOD1) cause hereditary variants of the fatal motor neuronal disease Amyotrophic lateral sclerosis (ALS). Pathophysiology of the disease is non-cell-autonomous: neurotoxicity is derived not only from mut
Externí odkaz:
https://doaj.org/article/8594083601d94213b35def1833a76df9
Publikováno v:
Physiological Research
We developed appropriate surgical procedures for single and repetitive multi-photon imaging of spinal cord in vivo. By intravenous anesthesia, artificial ventilation and laminectomy, acute experiments were performed in the dorsal and lateral white ma
Autor:
Eike D. Schomburg, Payam Dibaj
Publikováno v:
Physiological Research
Anesthetic and surgical procedures and an electrophysiological method were developed for recording nerve conduction velocity (NCV) of CNS fibers in the murine spinal cord. Under intravenous anesthesia and artificial ventilation the lumbar spinal cord
Publikováno v:
Neuroscience Research. 76:133-140
Investigation and interpretation of defective motor circuitries in transgenic mice required further basic results from wild-type mice. Therefore, we investigated the lumbar motor reflex pattern in anaesthetised mice using intracellular motoneuronal r
Autor:
Vladimir A. Maisky, Olena P. Mankivska, A. V. Maznychenko, Eike D. Schomburg, Olexandr V. Dovgan, Heinz Steffens, O. V. Vlasenko
Publikováno v:
Acta histochemica. 118(7)
The NADPH-diaphorase activity and Fos-immunoreactivity within the ventral horn of the lumbar spinal cord were studied in cats with acute unilateral myositis following injection of carrageenan into the m.m. gastrocnemius-soleus. In carrageenan-injecte
Autor:
Selva Baltan, Kathrin Kusch, Wenhui Huang, Iva D. Tzvetavona, Eike D. Schomburg, Aiman S. Saab, Heinz Steffens, Bianka Goetze, Christian Griesinger, Carlos Matute, Klaus-Armin Nave, Frank Kirchhoff, Alberto Pérez-Samartín, Payam Dibaj, Fernando Pérez-Cerdá, Wiebke Möbius, Johannes Hirrlinger, Hannah M. Jahn, Andrea Trevisiol, Siegrid Löwel, Davood Bakhtiari
Publikováno v:
Neuron
Oligodendrocytes make myelin and support axons metabolically with lactate. However, it is unknown how glucose utilization and glycolysis are adapted to the different axonal energy demands. Spiking axons release glutamate and oligodendrocytes express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399972c58c46da5a666244b577934266
https://www.zora.uzh.ch/id/eprint/127960/
https://www.zora.uzh.ch/id/eprint/127960/
Publikováno v:
Physiological Research
Electrophysiological investigations in mice, particularly with altered myelination, require reference data of the nerve conduction velocity (CV). CVs of different fibre groups were determined in the hindlimb of anaesthetized adult mice. Differentiati
Publikováno v:
Neuroscience Research. 72:155-162
The contribution of activated nociceptive muscle afferents to pathologically increased muscle tone remains obscure. The aim of the present study was to investigate whether an acute myositis of the gastrocnemius-soleus (GS) influences spinal reflex ac
Autor:
Eike D. Schomburg, Payam Dibaj, Frank Kirchhoff, Clemens Neusch, Jana Zschüntzsch, Heinz Steffens
Publikováno v:
Neuroscience Letters. 497:148-151
Pathophysiology of the motoneuron disease amyotrophic lateral sclerosis (ALS) is non-cell-autonomous. In mouse models of familiar ALS, neurotoxicity is derived not only from mutant motor neurons but also from mutant neighbouring glial cells. In vivo