Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Eik, Hoffmann"'
Autor:
Rob C. van Wijk, Ainhoa Lucía, Pavan Kumar Sudhakar, Lindsay Sonnenkalb, Cyril Gaudin, Eik Hoffmann, Bérénice Dremierre, Diana Angélica Aguilar-Ayala, Michael Dal Molin, Jan Rybniker, Stefano de Giorgi, Laura Cioetto-Mazzabò, Greta Segafreddo, Riccardo Manganelli, Giulia Degiacomi, Deborah Recchia, Maria Rosalia Pasca, Ulrika S.H. Simonsson, Santiago Ramón-García
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106411- (2023)
Summary: Tuberculosis (TB) is the historical leading cause of death by a single infectious agent. The European Regimen Accelerator for Tuberculosis (ERA4TB) is a public-private partnership of 30+ institutions with the objective to progress new anti-T
Externí odkaz:
https://doaj.org/article/cad837fcee6d48d4aec14cd52a9d0e2a
Autor:
Imène Belhaouane, Amine Pochet, Jonathan Chatagnon, Eik Hoffmann, Christophe J Queval, Nathalie Deboosère, Céline Boidin-Wichlacz, Laleh Majlessi, Valentin Sencio, Séverine Heumel, Alexandre Vandeputte, Elisabeth Werkmeister, Laurence Fievez, Fabrice Bureau, Yves Rouillé, François Trottein, Mathias Chamaillard, Priscille Brodin, Arnaud Machelart
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011192 (2023)
Progression of tuberculosis is tightly linked to a disordered immune balance, resulting in inability of the host to restrict intracellular bacterial replication and its subsequent dissemination. The immune response is mainly characterized by an orche
Externí odkaz:
https://doaj.org/article/b076df58fca44a32911ed45f8f9c632b
Autor:
Valentin Sencio, Arnaud Machelart, Cyril Robil, Nicolas Benech, Eik Hoffmann, Chloé Galbert, Lucie Deryuter, Séverine Heumel, Aline Hantute-Ghesquier, Anne Flourens, Priscille Brodin, Fabrice Infanti, Virgile Richard, Jean Dubuisson, Corinne Grangette, Thierry Sulpice, Isabelle Wolowczuk, Florence Pinet, Vincent Prévot, Sandrine Belouzard, François Briand, Martine Duterque-Coquillaud, Harry Sokol, François Trottein
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral infections. We herein hypothesized that disruption of gut homeostasis during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may associat
Externí odkaz:
https://doaj.org/article/550d4d66dfae45ffb125630022a5aad4
Autor:
Lowiese Desmarets, Nathalie Callens, Eik Hoffmann, Adeline Danneels, Muriel Lavie, Cyril Couturier, Jean Dubuisson, Sandrine Belouzard, Yves Rouillé
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The SARS-CoV-2 pandemic and the urgent need for massive antiviral testing highlighted the lack of a good cell-based assay that allowed for a fast, automated screening of antivirals in high-throughput content with minimal handling requirements in a BS
Externí odkaz:
https://doaj.org/article/a86dfe3734ce4ad68787b68d08d77489
Autor:
Sandrine Belouzard, Arnaud Machelart, Valentin Sencio, Thibaut Vausselin, Eik Hoffmann, Nathalie Deboosere, Yves Rouillé, Lowiese Desmarets, Karin Séron, Adeline Danneels, Cyril Robil, Loic Belloy, Camille Moreau, Catherine Piveteau, Alexandre Biela, Alexandre Vandeputte, Séverine Heumel, Lucie Deruyter, Julie Dumont, Florence Leroux, Ilka Engelmann, Enagnon Kazali Alidjinou, Didier Hober, Priscille Brodin, Terence Beghyn, François Trottein, Benoit Deprez, Jean Dubuisson
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010498 (2022)
Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in one or several geographical areas, to identify those exhibiting antiviral activity against
Externí odkaz:
https://doaj.org/article/ef24a1fe221949deb66833f87060787b
Autor:
Aurore Demars, Armelle Vitali, Audrey Comein, Elodie Carlier, Abdulkader Azouz, Stanislas Goriely, Justine Smout, Véronique Flamand, Mégane Van Gysel, Johan Wouters, Jan Abendroth, Thomas E Edwards, Arnaud Machelart, Eik Hoffmann, Priscille Brodin, Xavier De Bolle, Eric Muraille
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009887 (2021)
Brucellosis is one of the most widespread bacterial zoonoses worldwide. Here, our aim was to identify the effector mechanisms controlling the early stages of intranasal infection with Brucella in C57BL/6 mice. During the first 48 hours of infection,
Externí odkaz:
https://doaj.org/article/0ebdeb0dee1242609d7b967c5f88f4d6
Autor:
François Briand, Valentin Sencio, Cyril Robil, Séverine Heumel, Lucie Deruyter, Arnaud Machelart, Johanna Barthelemy, Gemma Bogard, Eik Hoffmann, Fabrice Infanti, Oliver Domenig, Audrey Chabrat, Virgile Richard, Vincent Prévot, Ruben Nogueiras, Isabelle Wolowczuk, Florence Pinet, Thierry Sulpice, François Trottein
Publikováno v:
Viruses, Vol 14, Iss 9, p 2067 (2022)
Obese patients with non-alcoholic steatohepatitis (NASH) are prone to severe forms of COVID-19. There is an urgent need for new treatments that lower the severity of COVID-19 in this vulnerable population. To better replicate the human context, we se
Externí odkaz:
https://doaj.org/article/e0f3dac631bc44eea379559d5efb400a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Toll-like receptors (TLRs) are at the forefront of pathogen recognition ensuring host fitness and eliciting protective cellular and humoral responses. Signaling pathways downstream of TLRs are tightly regulated for preventing collateral damage and lo
Externí odkaz:
https://doaj.org/article/f34cb8fa349941d8a85101ce177b40a2
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Intracellular bacteria are responsible for many infectious diseases in humans and have developed diverse mechanisms to interfere with host defense pathways. In particular, intracellular vacuoles are an essential niche used by pathogens to alter cellu
Externí odkaz:
https://doaj.org/article/aa02bef203fe4b5ba1f61624536700ca
Autor:
Inna S. Afonina, Eik Hoffmann
Publikováno v:
The FEBS journalReferences. 289(14)
This Special Issue of The FEBS Journal consists of 20 reviews covering various aspects and new developments in 'Infection and Immunity'. The issue includes expert views on the role of different immune cell populations, on the regulation of innate and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d25d403793e5f84ac3bc01abad377d5
https://pubmed.ncbi.nlm.nih.gov/35852038
https://pubmed.ncbi.nlm.nih.gov/35852038