Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Eijiro Watanabe"'
Autor:
Mayu Watanabe, Atsuko Nakatsuka, Kazutoshi Murakami, Kentaro Inoue, Takahiro Terami, Chigusa Higuchi, Akihiro Katayama, Sanae Teshigawara, Jun Eguchi, Daisuke Ogawa, Eijiro Watanabe, Jun Wada, Hirofumi Makino
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92647 (2014)
Phosphatidylethanolamine N-methyltransferase (Pemt) catalyzes the methylation of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) mainly in the liver. Under an obese state, the upregulation of Pemt induces endoplasmic reticulum (ER) stress b
Externí odkaz:
https://doaj.org/article/df6726209c6a4bc7bf107f246391af25
Autor:
Yuko Okada, Kazutaka Ikeda, Michihiro Matsumoto, Mashito Sakai, Yongheng Cao, Yasuhiro Takashima, Shigeo Ohta, Toshiyuki Mori, Naomi Kamimura, Ryuji Hiramatsu, Ryo Taguchi, Kyoko Nakamura, Hiroshi Sakaue, Tomoki Nagare, Kenjiro Inagaki, Masato Kasuga, Yasushi Matsuki, Eijiro Watanabe
Publikováno v:
Journal of Biological Chemistry. 286:37458-37469
Krüppel-like factor 15 (KLF15), a member of the Krüppel-like factor family of transcription factors, has been found to play diverse roles in adipocytes in vitro. However, little is known of the function of KLF15 in adipocytes in vivo. We have now f
Autor:
Kazuhiro Takahashi, Wataru Ogawa, Hiroshi Sakaue, Yasushi Matsuki, Hideyuki Gomi, Mototsugu Takashima, Eijiro Watanabe, Ryuji Hiramatsu, Masato Kasuga, Tomoki Nagare
Publikováno v:
Biochemical and Biophysical Research Communications. 379:98-103
KLF15 (Kruppel-like factor 15) plays a key role in adipocyte differentiation and glucose transport in adipocytes through activation of its target genes. We have now identified six target genes regulated directly by KLF15 in 3T3-L1 mouse adipocytes wi
Autor:
Jun Eguchi, Nozomu Wada, Sanae Teshigawara, Kazutoshi Murakami, Akihiro Katayama, Akinobu Takaki, Tetsuya Yasunaka, Daisuke Ogawa, Fusao Ikeda, Satoshi Yamaguchi, Jun Wada, Eijiro Watanabe, Makoto Matsuyama, Atsuko Nakatsuka
Publikováno v:
Scientific Reports
Although obesity is undoubtedly major risk for non-alcoholic steatohepatitis (NASH), the presence of lean NASH patients with normal body mass index has been recognized. Here, we report that the insufficiency of phosphatidylethanolamine N-methyltransf
Autor:
Kazuaki Miyake, Wataru Ogawa, Kiyoshi Teshigawara, Masato Kasuga, Ryuji Hiramatsu, Hiroshi Sakaue, Yasushi Matsuki, Eijiro Watanabe, Toshiyuki Mori, Hiroshi Inoue
Publikováno v:
Biochemical and Biophysical Research Communications. 327:920-926
Regulation of hepatic gene expression is important for energy homeostasis. We now show that hepatic expression of the gene for the transcription factor Kruppel-like factor 15 (KLF15) is increased by food deprivation and reduced by feeding in mice. Ex
Publikováno v:
Europe PubMed Central
The genomic RNA sequence of tobamovirus Ob (Ob), which can spread systemically in tobacco carrying the N gene, was determined. It consists of 6507 nucleotides and contains four open reading frames, exactly corresponding to the genomic organization of
Publikováno v:
Molecular and General Genetics MGG. 234:346-352
The sopA, B, C genes of the F plasmid play an essential role in plasmid partitioning during cell division in Escherichia coli. In this paper, the products of the sopA and sopB genes were isolated and their biochemical activities studied. [alpha-32P]A
Autor:
Shinichi, Kinoshita, Wataru, Ogawa, Yasuo, Okamoto, Mototsugu, Takashima, Hiroshi, Inoue, Yasushi, Matsuki, Eijiro, Watanabe, Ryuji, Hiramatsu, Masato, Kasuga
Publikováno v:
The Kobe journal of medical sciences. 54(4)
Regulation of hepatic gene expression is largely responsible for the control of nutrient metabolism. We previously showed that the transcription factor STAT3 regulates glucose homeostasis by suppressing the expression of gluconeogenic genes in the li
Autor:
Tetsuya Hosooka, Yasushi Matsuki, Eijiro Watanabe, Ryuji Hiramatsu, Tetsuya Noguchi, Masato Kasuga, Haruhisa Iguchi, Toyo Yoshioka, Wataru Ogawa, Mashito Sakai, Kenjiro Inagaki
Publikováno v:
Biochemical and biophysical research communications. 381(4)
The transcriptional regulator peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) controls mitochondrial biogenesis and energy homeostasis. Although physical exercise induces PGC-1alpha expression in muscle, the underlyin
Autor:
Sachie Nakamichi, Wataru Ogawa, Hiroshi Inoue, Ryuji Hiramatsu, Eijiro Watanabe, Aki Emi, Yoko Senga, Yasushi Matsuki, Masato Kasuga
Publikováno v:
Journal of molecular endocrinology. 42(2)
Gene related to anergy in lymphocytes (GRAIL) is an E3 ubiquitin ligase that regulates energy in T-lymphocytes. Whereas, the relevance of GRAIL to T lymphocyte function is well established, the role of this protein in other cell types remains unknown