Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Eiji Yamato"'
Autor:
Masaki Kobayashi, Eiji Yamato, Koji Tanabe, Fumi Tashiro, Satsuki Miyazaki, Jun-ichi Miyazaki
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151927 (2016)
Elucidating the regulation of glucose-stimulated insulin secretion (GSIS) in pancreatic β cells is important for understanding and treating diabetes. The pancreatic β cell line, MIN6, retains GSIS but gradually loses it in long-term culture. The MI
Externí odkaz:
https://doaj.org/article/49180fa4aa334a2caf0b24e5cda1ab2e
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61211 (2013)
Elucidating the regulation of glucose-stimulated insulin secretion (GSIS) in pancreatic islet β cells is important for understanding and treating diabetes. MIN6 cells, a transformed β-cell line derived from a mouse insulinoma, retain GSIS and are a
Externí odkaz:
https://doaj.org/article/88ace9e7355042f688681bdcefe1f9da
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47536 (2012)
Tubular complexes (TCs) are aggregates of duct-like monolayered cells in the developing and regenerating pancreas. Recent studies showed that TCs have regenerative potential, including islet neogenesis. We previously delivered adenovirus vector (AdV)
Externí odkaz:
https://doaj.org/article/dfe2780485d848b5a85fe2d6fba643e6
Autor:
Eiji Yamato
Publikováno v:
Hormone and Metabolic Research.
Repressor element-1 silencing transcription factor (Rest) is not expressed in pancreatic beta cells and neuronal cells. However, Rest4, a truncated form of Rest, is expressed in high passaged MIN6 (HP-MIN6) cells, a pancreatic beta cell line that los
Publikováno v:
栄養科学研究. 7:1-5
幼少時に身についた食習慣は、成人以降の食行動に影響することが考えられる。本研究では、2型糖尿病患者における幼少時の菓子類の摂取が、現在の食行動特性に与える影響について
Autor:
Eiji Yamato
Publikováno v:
Endocrine Regulations, Vol 52, Iss 1, Pp 21-26 (2018)
Objective. Histone deacytylase inhibitors (HDACis) inhibit the deacetylation of the lysine residue of proteins, including histones, and regulate the transcription of a variety of genes. Recently, HDACis have been used clinically as anti-cancer drugs
Autor:
Tatsuo Furuyama, Shinobu Inagaki, Rie Minamida, Jun-ichi Miyazaki, Eiji Yamato, Satsuki Miyazaki, Fumi Tashiro
Publikováno v:
Genes to Cells. 17:758-767
Several reports have suggested that Foxo1, a key regulator in differentiation, growth and metabolism, is involved in pancreatic β-cell function. However, detailed analyses have been hampered by a lack of Foxo1-deficient β cells. To elucidate Foxo1'
Publikováno v:
Journal of Diabetes Investigation. 3:41-51
Aims/Introduction: We recently established a strategy for isolating multipotential duct-like cells, called pdx-1-positive pancreatic cell-derived (PPPD) cells, from the pancreas. To analyze the molecular mechanisms of pancreatic cell differentiation,
Autor:
Yamamoto Tsunehiko, Jun-ichi Miyazaki, Hiroshi Ikegami, Hidenori Taniguchi, Satsuki Miyazaki, Yusuke Moritoh, Fumi Tashiro, Keiko Ozato, Eiji Yamato
Publikováno v:
Diabetes
OBJECTIVE Retinoid X receptors (RXRs) are members of the nuclear hormone receptor superfamily and are thought to be key regulators in differentiation, cellular growth, and gene expression. Although several experiments using pancreatic β-cell lines h
Autor:
Satsuki Miyazaki, Hayato Kawakami, Shuichi Toyoda, Masami Kanai-Azuma, Fumi Tashiro, Eiji Yamato, Tomofumi Tanaka, Tatsushi Miyazaki, Jun-ichi Miyazaki, Masahiro Kato
Publikováno v:
Genes to Cells. 15:813-828
In a search for genes specifically expressed in mouse embryonic stem cells, we identified one we called Ces5. We found that it corresponded to the Ooep gene, which was recently reported to be expressed specifically in oocytes. Mouse Ces5/Ooep, also c