Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Eiji Yamato"'
Autor:
Eiji Yamato
Publikováno v:
Hormone and Metabolic Research.
Repressor element-1 silencing transcription factor (Rest) is not expressed in pancreatic beta cells and neuronal cells. However, Rest4, a truncated form of Rest, is expressed in high passaged MIN6 (HP-MIN6) cells, a pancreatic beta cell line that los
Akademický článek
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Autor:
Masaki Kobayashi, Eiji Yamato, Koji Tanabe, Fumi Tashiro, Satsuki Miyazaki, Jun-ichi Miyazaki
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151927 (2016)
Elucidating the regulation of glucose-stimulated insulin secretion (GSIS) in pancreatic β cells is important for understanding and treating diabetes. The pancreatic β cell line, MIN6, retains GSIS but gradually loses it in long-term culture. The MI
Externí odkaz:
https://doaj.org/article/49180fa4aa334a2caf0b24e5cda1ab2e
Publikováno v:
栄養科学研究. 7:1-5
幼少時に身についた食習慣は、成人以降の食行動に影響することが考えられる。本研究では、2型糖尿病患者における幼少時の菓子類の摂取が、現在の食行動特性に与える影響について
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61211 (2013)
Elucidating the regulation of glucose-stimulated insulin secretion (GSIS) in pancreatic islet β cells is important for understanding and treating diabetes. MIN6 cells, a transformed β-cell line derived from a mouse insulinoma, retain GSIS and are a
Externí odkaz:
https://doaj.org/article/88ace9e7355042f688681bdcefe1f9da
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47536 (2012)
Tubular complexes (TCs) are aggregates of duct-like monolayered cells in the developing and regenerating pancreas. Recent studies showed that TCs have regenerative potential, including islet neogenesis. We previously delivered adenovirus vector (AdV)
Externí odkaz:
https://doaj.org/article/dfe2780485d848b5a85fe2d6fba643e6
Autor:
Eiji Yamato
Publikováno v:
Endocrine Regulations, Vol 52, Iss 1, Pp 21-26 (2018)
Objective. Histone deacytylase inhibitors (HDACis) inhibit the deacetylation of the lysine residue of proteins, including histones, and regulate the transcription of a variety of genes. Recently, HDACis have been used clinically as anti-cancer drugs
Autor:
Tatsuo Furuyama, Shinobu Inagaki, Rie Minamida, Jun-ichi Miyazaki, Eiji Yamato, Satsuki Miyazaki, Fumi Tashiro
Publikováno v:
Genes to Cells. 17:758-767
Several reports have suggested that Foxo1, a key regulator in differentiation, growth and metabolism, is involved in pancreatic β-cell function. However, detailed analyses have been hampered by a lack of Foxo1-deficient β cells. To elucidate Foxo1'
Publikováno v:
Journal of Diabetes Investigation. 3:41-51
Aims/Introduction: We recently established a strategy for isolating multipotential duct-like cells, called pdx-1-positive pancreatic cell-derived (PPPD) cells, from the pancreas. To analyze the molecular mechanisms of pancreatic cell differentiation,
Autor:
Yamamoto Tsunehiko, Jun-ichi Miyazaki, Hiroshi Ikegami, Hidenori Taniguchi, Satsuki Miyazaki, Yusuke Moritoh, Fumi Tashiro, Keiko Ozato, Eiji Yamato
Publikováno v:
Diabetes
OBJECTIVE Retinoid X receptors (RXRs) are members of the nuclear hormone receptor superfamily and are thought to be key regulators in differentiation, cellular growth, and gene expression. Although several experiments using pancreatic β-cell lines h