Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eiji Yamasaki"'
Autor:
Zhihong Wu, Tetsuro Miki, Jun Nakura, Michiya Igase, Tokihisa Nagai, Eiji Yamasaki, Katsuhiko Kohara, Jing Ji Jin, Miyuki Yamamoto, Michiko Abe, Yasuharu Tabara
Publikováno v:
Hypertension Research. 29:227-232
Serotonin has been implicated in the pathogenesis of hypertension because of its ability to induce vasoconstriction via stimulation of serotonin 2 (5-HT2) receptors. Recently, an association between the T102C functional polymorphism of the serotonin
Publikováno v:
Electronics and Communications in Japan (Part II: Electronics). 88:19-26
We propose a new high-efficiency CMOS charge pump circuit that generates a high positive or negative voltage by using a low operating voltage of 1.5 V. By controlling the body voltage and boosting the gate voltage of the nMOSFET, the back bias effect
Autor:
Shinichi Tamura, Y. Imai, Toshihiko Nagase, Shuzo Noda, Masami Inada, Eiji Yamasaki, Yoshiaki Inui, Yuji Matsuzawa, Sumio Kawata, Yukihiko Matsuda, Nobuyuki Ito
Publikováno v:
British Journal of Cancer
Chemotherapy is not effective for hepatocellular carcinoma (HCC). HMG-CoA redutase inhibitors have cytostatic activity for cancer cells, but their clinical usefulness is unknown. To investigate whether pravastatin, a potent HMG-CoA reductase inhibito
Autor:
Eiji Yamasaki, Norio Tominaga
Publikováno v:
Energy Policy. 25:903-912
The development of an aged society, paired with a growing number of elderly households, is expected to increase residential energy demand. This study is designed to analyze various factors which determine the energy demand of elderly households and t
Autor:
Yoshiaki Inui, Yukihiko Matsuda, H Mitsui, Yuji Matsuzawa, J Miyagawa, H Ishiguro, Eiji Yamasaki, Toshihiko Nagase, Toshifumi Ito, Sumio Kawata, K. Yamamoto, Shinichi Tamura, M Kinoshita
Publikováno v:
British Journal of Cancer
Recently, many inhibitors of farnesyl protein transferase (FPTase) have been identified. Some of them interrupt cell growth in addition to Ras and nuclear lamin processing of Ras-transformed cells. We have tested the effect of the FPTase inhibitors m
Autor:
Toshihiko Nagase, Yoshiaki Inui, Yuji Matsuzawa, Toshio Ito, Yukihiko Matsuda, Eiji Yamasaki, Shinji Tamura, Hiroshi Ishiguro, Sumio Kawata
Publikováno v:
International Journal of Cancer. 65:620-626
So far, treatment with anti-cancer agents has failed to achieve satisfactory results in hepatocellular carcinoma. In the process of hepatocarcinogenesis, ras has been shown to play a role, ras requires a farnesyl moiety for activation. It has been fo
Autor:
Shigeru Fujii, Yukihiko Matsuda, Sumio Kawata, Yuji Matsuzawa, Eiji Yamasaki, Hiroshi Ishiguro
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 663:35-42
An HPLC assay for farnesyl-protein transferase activity using a dabsylated peptide is described. The substrates used were a synthetic dabsylated nonapeptide, N-dabsyl-L-serinyl-L-methioninyl-L-glycinyl-L-++ +leucinyl-L-prolinyl-L-cysteinyl- L-valinyl
Publikováno v:
British Journal of Cancer
Modulation of cell growth by a combination of pravastatin [a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor] and d-limonene (an inhibitor of protein isoprenylation) was studied using Hep G2, a human hepatoma-derived cell line. Pr
Autor:
Sumio Kawata, Yuichi Maeda, Toshihiko Nagase, Hiroshi Ishiguro, Yuji Matsuzawa, Eiji Yamasaki, Shinichi Kiso, Yukihiko Matsuda
Publikováno v:
Cancer. 73:53-57
Background. Modulation of serum levels of circulating cytokines and inflammatory responses with a serine protease inhibitor was studied in 34 patients with hepatocellular carcinoma (HCC) after transcatheter arterial embolization (TAE). Methods. The 3
Autor:
Yoshiaki Inui, Yuji Matsuzawa, Hiroki Kakimoto, Hiroshi Ishiguro, Sumio Kawata, Eiji Yamasaki
Publikováno v:
Japanese Journal of Cancer Research : Gann
3‐Hydroxy‐3‐methylglutaryl‐coenzyme A (HMG‐CoA) reductase inhibitor is known to have an inhibitory effect on cell growth in addition to a cholesterol‐lowering effect. This study examined the effect of pravastatin, a potent inhibitor of HM