Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Eiji Honda"'
Autor:
Hajime Takashima, Atsushi Yoshimori, Eiji Honda, Tomonori Taguri, Jun Ozawa, Masaji Kasai, Satoshi Shuto, Dai Takehara
Publikováno v:
ACS Omega, Vol 6, Iss 40, Pp 26601-26612 (2021)
Externí odkaz:
https://doaj.org/article/2f136a2a8e164a58908361d488e302f5
Autor:
Kumiko Tsuihiji, Eiji Honda, Kanehisa Kojoh, Shizue Katoh, Tomonori Taguri, Atsushi Yoshimori, Hajime Takashima
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1506 (2022)
Currently, various pharmaceutical modalities are being developed rapidly. Targeting protein–protein interactions (PPIs) is an important objective in such development. Cyclic peptides, because they have good specificity and activity, have been attra
Externí odkaz:
https://doaj.org/article/08221a0e1c484e92919013e466985320
Autor:
Eiji Honda, Tomonori Taguri, Atsushi Yoshimori, Dai Takehara, Jun Ozawa, Masaji Kasai, Hajime Takashima, Satoshi Shuto
Publikováno v:
ACS Omega, Vol 6, Iss 40, Pp 26601-26612 (2021)
ACS Omega
ACS Omega
Protein–protein interactions (PPIs) are fundamentally important and challenging drug targets. Peptidomimetic molecules of various types have been developed to modulate PPIs. A particularly promising drug discovery strategy, structural peptidomimeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf9f44a14f478e8e34dab16b12a8e51
https://doi.org/10.1021/acsomega.1c03967
https://doi.org/10.1021/acsomega.1c03967
Autor:
Hitoshi Kawashima, Ryuta Shiraki, Hiroyuki Matsuura, Kazuhiro Ikeda, Ken-ichi Sato, Yojiro Mori, Keijiro Suzuki, Eiji Honda, Shu Namiki
Publikováno v:
Journal of Lightwave Technology. 38:1002-1009
With the recent growth of network traffic demands, a high-capacity optical-path network based on reconfigurable optical add-drop multiplexers (ROADMs) is highly desirable. Among the various technologies available, extending the useable frequency band
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f09499c58865de695256427389f6797c
https://doi.org/10.1109/jlt.2019.2947709
https://doi.org/10.1109/jlt.2019.2947709
Publikováno v:
ECOC
We verify the feasibility of the optical circuit switch architecture for intra-datacentre networks based on spatial super-channels using DP-QPSK, DP-8QAM, and DP-16QAM signals. Simulations clarify the maximum throughput attainable with each modulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a38eb28cfada330b5e36dbc89517b3a8
https://doi.org/10.1109/ecoc48923.2020.9333047
https://doi.org/10.1109/ecoc48923.2020.9333047
Publikováno v:
2020 Opto-Electronics and Communications Conference (OECC).
We evaluate the feasibility of an optical circuit switch that suits SDM-based intra-datacenter networks. Simulations with 100-Gbps DP-QPSK signals and 200-Gbps DP-16QAM signals clarify the maximum switch throughput attainable with feasible hardware r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5794d2f011a2e228b375455140b182c
https://doi.org/10.1109/oecc48412.2020.9273537
https://doi.org/10.1109/oecc48412.2020.9273537
High-Throughput Optical Circuit Switch for Intra-Datacenter Networks Based on Spatial Super-Channels
Publikováno v:
OFC
We propose a novel optical circuit switch architecture based on spatial super-channels. We construct part of a 1,536×1,536 optical switch and its performance is experimentally confirmed. The total throughput of the switch reaches 2.1 Pbps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc7e4adb72d87a3b987a94e64bbc26d
https://doi.org/10.1364/ofc.2020.w1f.2
https://doi.org/10.1364/ofc.2020.w1f.2
Publikováno v:
OECC/PSC
This paper analyzes the performance of a commercially available wavelength-tunable laser for developing a large-scale (1,424 ×1,424) optical circuit switch intended for datacenter/HPC applications. The dynamic BER transitions of 100-Gbps DP-QPSK sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdc780b589de5ecefb190f8b5e688c09
https://doi.org/10.23919/ps.2019.8817773
https://doi.org/10.23919/ps.2019.8817773
Publikováno v:
45th European Conference on Optical Communication (ECOC 2019).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7fd975aef97aad0512bfd02f32fb8c
https://doi.org/10.1049/cp.2019.0966
https://doi.org/10.1049/cp.2019.0966
Autor:
Takafumi, Takai, Tatsuki, Koike, Eiji, Honda, Yuichi, Kajita, Minoru, Nakamura, Sachie, Morimoto, Yasutaka, Hoashi, Makoto, Kamata, Tomomichi, Watanabe, Tomoko, Igari, Jun, Terauchi
Publikováno v:
Bioorganicmedicinal chemistry. 23(9)
Novel piperazine derivatives as γ-secretase modulators (GSMs) were prepared and tested for their ability to selectively lower Aβ₄₂ production. Lead compound 3, with selective Aβ₄₂-lowering activity, was modified by replacing its imidazolyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24710a8089d86bbc54e4d10a33624eb6
https://pubmed.ncbi.nlm.nih.gov/25842363
https://pubmed.ncbi.nlm.nih.gov/25842363