Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Eijdems, EWHM"'
Autor:
Broekstra R; University Medical Center Groningen, Department of Health Sciences, Section Health Psychology, University of Groningen, 9712 CP Groningen, The Netherlands., Campmans-Kuijpers MJE; University Medical Center Groningen, Department of Gastroenterology and Hepatology, University of Groningen, 9712 CP Groningen, The Netherlands., Dijkstra G; University Medical Center Groningen, Department of Gastroenterology and Hepatology, University of Groningen, 9712 CP Groningen, The Netherlands., Ranchor AV; University Medical Center Groningen, Department of Health Sciences, Section Health Psychology, University of Groningen, 9712 CP Groningen, The Netherlands., Eijdems EWHM; University Medical Center Groningen, University of Groningen, 9712 CP Groningen, The Netherlands.
Publikováno v:
Journal of personalized medicine [J Pers Med] 2023 Mar 29; Vol. 13 (4). Date of Electronic Publication: 2023 Mar 29.
Autor:
van der Stijl R; University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; UMCG Research BV, University Medical Center Groningen, Groningen, The Netherlands.; BBMRI.nl, Biobanking and Biomolecular Resources Research Infrastructure, The Netherlands., Manders P; Radboud Biobank, Radboud University Medical Center, Nijmegen, The Netherlands., Eijdems EWHM; University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; BBMRI.nl, Biobanking and Biomolecular Resources Research Infrastructure, The Netherlands.
Publikováno v:
Biopreservation and biobanking [Biopreserv Biobank] 2021 Jun; Vol. 19 (3), pp. 228-240. Date of Electronic Publication: 2021 May 27.
Autor:
Graham, Matthew1 (AUTHOR), Samuel, Gabrielle1 (AUTHOR) gabrielle.samuel@kcl.ac.uk, Farley, Martin2 (AUTHOR)
Publikováno v:
Journal of Translational Medicine. 8/8/2024, Vol. 22 Issue 1, p1-15. 15p.
Autor:
EIJDEMS, EWHM, ZAMAN, GJR, DEHAAS, M, VERSANTVOORT, CHM, FLENS, MJ, SCHEPER, RJ, KAMST, E, BORST, P, BAAS, F
Publikováno v:
British Jounal of Cancer, 72(2), 298-306. Nature Publishing Group
We have analysed the contribution of several parameters, e.g. drug accumulation, MDR1 P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and topoisomerase (topo) II, to drug resistance in a large set of drug-resistant variants of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::7617b2afec9aea60de611fea33d3f821
https://research.rug.nl/en/publications/383e63c4-559e-4e36-b570-ca3fc726adbc
https://research.rug.nl/en/publications/383e63c4-559e-4e36-b570-ca3fc726adbc
MECHANISMS OF MRP OVER-EXPRESSION IN 4 HUMAN LUNG-CANCER CELL-LINES AND ANALYSIS OF THE MRP AMPLICON
Autor:
EIJDEMS, EWHM, DEHAAS, M, COCOMARTIN, JM, OTTENHEIM, CPE, ZAMAN, GJR, DAUWERSE, HG, BREUNING, MH, TWENTYMAN, PR, BORST, P, BAAS, F
Publikováno v:
International Journal of Cancer, 60(5), 676-684. Wiley
Some multidrug resistant cell lines over-express the gene encoding the multidrug-resistance-associated protein (MRP). In all cell lines reported thus far, over-expression is associated with gene amplification. We have studied the predominant mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::294ec827f19944ec30377d12a79eaeb1
https://research.rug.nl/en/publications/b2680a5d-9ff0-4478-a3c2-9452afaf0fef
https://research.rug.nl/en/publications/b2680a5d-9ff0-4478-a3c2-9452afaf0fef
Autor:
EIJDEMS, EWHM, DEHAAS, M, TIMMERMAN, AJ, VANDERSCHANS, GP, KAMST, E, DENOOIJ, J, RICOTTI, GCBA, BORST, P, BAAS, F
Publikováno v:
British Jounal of Cancer, 71(1), 40-47. Nature Publishing Group
Multidrug-resistant (MDR) cell lines often have a compound phenotype, combining reduced drug accumulation with a decrease in topoisomerase II. We have analysed alterations in topoisomerase II in MDR derivatives of the human lung cancer cell line SW-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::de83fdd507dbebb0769501b408202a6e
https://research.rug.nl/en/publications/a1bbad05-c6c8-4307-bfa0-d0060f165ef0
https://research.rug.nl/en/publications/a1bbad05-c6c8-4307-bfa0-d0060f165ef0
Autor:
ZAMAN, GJR, VERSANTVOORT, CHM, SMIT, JJM, EIJDEMS, EWHM, DEHAAS, M, SMITH, AJ, BROXTERMAN, HJ, MULDER, NH, DEVRIES, EGE, BAAS, F, BORST, P
Publikováno v:
Cancer Research, 53(8), 1747-1750. AMER ASSOC CANCER RESEARCH
Human cells can become multidrug resistant (MDR) by an increase in the activity of the MDR1 P-glycoprotein or by other, as vet unknown mechanisms, referred to as non-P-glycoprotein mediated MDR (non-Pgp MDR). S. P. C. Cole et al. [Science (Washington
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::9bb4b2a107af946c25c51487675dce54
https://research.rug.nl/en/publications/704ebabe-6983-4e19-ad8d-b32fdc103995
https://research.rug.nl/en/publications/704ebabe-6983-4e19-ad8d-b32fdc103995
Autor:
BORST, P, SCHINKEL, AH, SMIT, JJM, Wagenaar, E, VANDEEMTER, L, SMITH, AJ, EIJDEMS, EWHM, BAAS, F, ZAMAN, GJR
Publikováno v:
Pharmacology & Therapeutics, 60(2), 289-299. PERGAMON-ELSEVIER SCIENCE LTD
In this paper, we review recent work on multidrug resistance (MDR) in Amsterdam. We have generated mice homozygous for a disruption of one of their P-glycoprotein (Pgp) genes. The mutations do not interfere with viability or fertility, showing that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::e52e8840c8fb1265f3fe9a9dba7e91f8
https://research.rug.nl/en/publications/c8168ccd-b4d6-4ca9-afaf-4ca35834538b
https://research.rug.nl/en/publications/c8168ccd-b4d6-4ca9-afaf-4ca35834538b
Autor:
EIJDEMS, EWHM, BORST, P, JONGSMA, APM, de Jong, Steven, DEVRIES, EGE, VANGROENIGEN, M, VERSANTVOORT, CHM, NIEUWINT, AWM, BAAS, F
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 89(8), 3498-3502. NATL ACAD SCIENCES
A non-P-glycoprotein-mediated mechanism of multidrug resistance (non-Pgp MDR) bas been identified in doxorubicin-selected sublines of the human non-small cell lung carcinoma cell lines SW-1573. These sublines are cross-resistant to daunorubicin, VP16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::5d4de8e185d0b1fdcd2794e4965dbc7d
https://research.rug.nl/en/publications/ce3a9983-e1a0-4cb7-a2cf-b44c8bed9013
https://research.rug.nl/en/publications/ce3a9983-e1a0-4cb7-a2cf-b44c8bed9013
Autor:
Eijdems, EWHM, de Haas, M, Timmerman, AJ, Van der Schans, GP, Kamst, E, de Nooij, J, Astaldi Ricotti, GC, Borst, P, Baas, F, Eijdems, E W, Timmerman, A J, Van der Schans, G P, Astaldi Ricotti, G C
Publikováno v:
British Journal of Cancer; Jan1995, Vol. 71 Issue 1, p40-47, 8p