Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Eija A, Kalso"'
Autor:
Fredrik H.G. Ahlström, Hanna Viisanen, Leena Karhinen, Vidya Velagapudi, Kim J. Blomqvist, Tuomas O. Lilius, Pekka V. Rauhala, Eija A. Kalso
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 38-51 (2024)
First-line pharmacotherapy for peripheral neuropathic pain (NP) of diverse pathophysiology consists of antidepressants and gabapentinoids, but only a minority achieve sufficient analgesia with these drugs. Opioids are considered third-line analgesics
Externí odkaz:
https://doaj.org/article/5c91e15f7536415f807a084410abc93d
Publikováno v:
Therapeutic Advances in Psychopharmacology, Vol 11 (2021)
Liquorice has a long history of use in traditional Chinese, Ayurvedic and herbal medicine. The liquorice plant contains numerous bioactive compounds, including triterpenes, flavonoids and secondary metabolites, with glycyrrhizin being the main active
Externí odkaz:
https://doaj.org/article/548f050fca594341934ac88179d6665a
Autor:
Rae F. Bell, Eija A. Kalso
Publikováno v:
PAIN Reports, Vol 4, Iss 3, p e731 (2019)
Externí odkaz:
https://doaj.org/article/0e26841c4d814d38a21b56d141cbfaef
Autor:
Johanna Kujala, Niklas Wester, Terhi J. Lohela, Mika Kurkela, Janne T. Backman, Björn Mikladal, Tomi Laurila, Jari Koskinen, Tuomas O. Lilius, Eija A. Kalso
Publikováno v:
British Journal of Clinical Pharmacology.
Autor:
Sirkku E. Ahlström, Paula H. Bergman, Ritva M. Jokela, Klaus T. Olkkola, Mari A. Kaunisto, Eija A. Kalso
Publikováno v:
Acta Anaesthesiologica Scandinavica.
Autor:
Kim J. Blomqvist, Moritz O.B. Skogster, Mika J. Kurkela, Marko P. Rosenholm, Fredrik H.G. Ahlström, Mikko T. Airavaara, Janne T. Backman, Pekka V. Rauhala, Eija A. Kalso, Tuomas O. Lilius
Publikováno v:
Blomqvist, K J, Skogster, M O B, Kurkela, M J, Rosenholm, M P, Ahlström, F H G, Airavaara, M T, Backman, J T, Rauhala, P V, Kalso, E A & Lilius, T O 2022, ' Systemic hypertonic saline enhances glymphatic spinal cord delivery of lumbar intrathecal morphine ', Journal of Controlled Release, vol. 344, pp. 214-224 . https://doi.org/10.1016/j.jconrel.2022.03.022
The blood-brain barrier significantly limits effective drug delivery to central nervous system (CNS) targets. The recently characterized glymphatic system offers a perivascular highway for intrathecally (i.t.) administered drugs to reach deep brain s
Autor:
Rae Frances Bell, Eija Anneli Kalso
Publikováno v:
PAIN Reports, Vol 3, Iss 5, p e674 (2018)
Externí odkaz:
https://doaj.org/article/38c40dbcab4c4b6983505d8fe7f4233a
Autor:
Yulia A. Sidorova, Maxim M. Bespalov, Agnes W. Wong, Oleg Kambur, Viljami Jokinen, Tuomas O. Lilius, Ilida Suleymanova, Gunnar Karelson, Pekka V. Rauhala, Mati Karelson, Peregrine B. Osborne, Janet R. Keast, Eija A. Kalso, Mart Saarma
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Neuropathic pain caused by nerve damage is a common and severe class of chronic pain. Disease-modifying clinical therapies are needed as current treatments typically provide only symptomatic relief; show varying clinical efficacy; and most have signi
Externí odkaz:
https://doaj.org/article/386952903bfa44e9aacfe166bb459eff
Sleep Well and Recover Faster with Less Pain—A Narrative Review on Sleep in the Perioperative Period
Autor:
Reetta M. Sipilä, Eija A. Kalso
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 2000, p 2000 (2021)
Sleep disturbance, pain, and having a surgical procedure of some kind are all very likely to occur during the average lifespan. Postoperative pain continues to be a prevalent problem and growing evidence supports the association between pain and slee
Autor:
Tuomas O. Lilius, Kim Blomqvist, Natalie L. Hauglund, Guojun Liu, Frederik Filip Stæger, Simone Bærentzen, Ting Du, Fredrik Ahlström, Janne T. Backman, Eija A. Kalso, Pekka V. Rauhala, Maiken Nedergaard
Publikováno v:
Journal of Controlled Release
Lilius, T O, Blomqvist, K, Hauglund, N L, Liu, G, Stæger, F F, Baerentzen, S, Du, T, Ahlstrom, F, Backman, J T, Kalso, E A, Rauhala, P V & Nedergaard, M 2019, ' Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs ', Journal of Controlled Release, vol. 304, pp. 29-38 . https://doi.org/10.1016/j.jconrel.2019.05.005
Lilius, T O, Blomqvist, K, Hauglund, N L, Liu, G, Stæger, F F, Baerentzen, S, Du, T, Ahlstrom, F, Backman, J T, Kalso, E A, Rauhala, P V & Nedergaard, M 2019, ' Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs ', Journal of Controlled Release, vol. 304, pp. 29-38 . https://doi.org/10.1016/j.jconrel.2019.05.005
Drug delivery to the central nervous system remains a major problem due to biological barriers. The blood-brainbarrier can be bypassed by administering drugs intrathecally directly to the cerebrospinal fluid (CSF). The glymphatic system, a network of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230d7603dbc2bfcd0b09c8ceeb5a65e8
http://hdl.handle.net/10138/307810
http://hdl.handle.net/10138/307810