Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eija, Koponen"'
Autor:
Maija Castrén, Katariina E Lampinen, Riitta Miettinen, Eija Koponen, Ilkka Sipola, Cathy E Bakker, Ben A Oostra, Eero Castrén
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 221-229 (2002)
Both fragile X mental retardation protein (FMRP) and brain-derived neurotrophic factor (BDNF) are implicated in the maturation of neurons and in the higher cognitive functions. We have investigated whether FMRP and BDNF are reciprocally regulated in
Externí odkaz:
https://doaj.org/article/464ffc8ecfda4074b8d09e61e0b47f70
Publikováno v:
University of Helsinki
Europe PubMed Central
Europe PubMed Central
Noncompetitive NMDA receptor antagonists such as phencyclidine and MK-801 produce psychotropic symptoms that closely resemble schizophrenic psychosis and induce the expression of immediate early genes in limbic cortical areas. We are concentrating on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60ed078b2f9f9f150eca0a3f086338f
https://doi.org/10.1111/j.1749-6632.2000.tb06720.x
https://doi.org/10.1111/j.1749-6632.2000.tb06720.x
Autor:
Ewen MacDonald, Eija Koponen, Vootele Voikar, Tommi Saarelainen, Eero Castrén, Tomi Rantamäki
Publikováno v:
Cellular and Molecular Neurobiology. 25:973-980
1. Neurotrophins and serotonin have both been implicated in the pathophysiology of depression and in the mechanisms of antidepressant treatments. 2. Brain-derived neurotrophic factor (BDNF) influences the growth and plasticity of serotonergic (5-HT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0516ed9f275cd9504305020f7a508899
https://doi.org/10.1007/s10571-005-8468-z
https://doi.org/10.1007/s10571-005-8468-z
Publikováno v:
Molecular Brain Research. 130:81-94
Significant body of evidence indicates an important role for brain-derived neurotrophic factor (BDNF) in the hippocampal synaptic plasticity; however, the exact mechanisms how the BDNF signal is converted to plastic changes during memory processes ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c044a9bbb040edf9f1dee91c7b55b7c2
https://doi.org/10.1016/j.molbrainres.2004.07.010
https://doi.org/10.1016/j.molbrainres.2004.07.010
Publikováno v:
European Journal of Neuroscience. 15:721-734
Brain derived neurotrophic factor (BDNF) has been suggested to be involved in epileptogenesis. Both pro- and antiepileptogenic effects have been reported, but the exact physiological role is still unclear. Here, we investigated the role of endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f101efe0078b28909a8a271e15dddee1
https://doi.org/10.1046/j.1460-9568.2002.01897.x
https://doi.org/10.1046/j.1460-9568.2002.01897.x
Autor:
Olli Gröhn, Risto A. Kauppinen, Jari Koistinaho, Jouko A. Lukkarinen, Eija Koponen, Jukka Jolkkonen, Susanna Koponen, Eero Castrén, Garry Wong, Annakaisa Haapasalo, Tommi Saarelainen, Leena Alhonen
Publikováno v:
Molecular and Cellular Neuroscience. 16:87-96
It has been suggested that the increased production of endogenous BDNF after brain insults supports the survival of injured neurons and limits the spread of the damage. In order to test this hypothesis experimentally, we have produced transgenic mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7293c3fdc311b1ba24bb48d701ba108
https://doi.org/10.1006/mcne.2000.0863
https://doi.org/10.1006/mcne.2000.0863
Autor:
Tuomas Rauramaa, Heikki Rauvala, Eija Koponen, Ruusu Riekki, Eero Castrén, Tomi Taira, Vootele Voikar, Tommi Saarelainen
Publikováno v:
Molecular and cellular neurosciences. 26(1)
We have investigated the biochemical, physiological, and behavioral properties of transgenic mice overexpressing the full-length neurotrophin receptor trkB (trkB.TK+). The highest trkB.TK+ mRNA overexpression was achieved in the cerebral cortex and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad1a2d10a447059e2604cfa8c922a45
https://pubmed.ncbi.nlm.nih.gov/15121188
https://pubmed.ncbi.nlm.nih.gov/15121188
Publikováno v:
Neuroscience letters. 350(1)
Non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists produce toxic effects in the limbic cortex of rodent brain. NMDA antagonists also increase the expression of brain-derived neurotrophic factor (BDNF) mRNA in the same brain areas. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03f1fd285e272eabd84dd24ff9b6021
https://pubmed.ncbi.nlm.nih.gov/12962903
https://pubmed.ncbi.nlm.nih.gov/12962903
Autor:
Cathy E. Bakker, Ben A. Oostra, Ilkka Sipola, Katariina E Lampinen, Eija Koponen, Eero Castrén, Riitta Miettinen, Maija L. Castrén
Publikováno v:
Neurobiology of Disease, 11, 221-229. Academic Press
Neurobiology of Disease, Vol 11, Iss 1, Pp 221-229 (2002)
Neurobiology of Disease, Vol 11, Iss 1, Pp 221-229 (2002)
Both fragile X mental retardation protein (FMRP) and brain-derived neurotrophic factor (BDNF) are implicated in the maturation of neurons and in the higher cognitive functions. We have investigated whether FMRP and BDNF are reciprocally regulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0495b2de1d2fa92fc771a7991cd2af9c
https://pubmed.ncbi.nlm.nih.gov/12460560
https://pubmed.ncbi.nlm.nih.gov/12460560
Autor:
Sari, Lähteinen, Asla, Pitkänen, Tommi, Saarelainen, Jari, Nissinen, Eija, Koponen, Eero, Castrén
Publikováno v:
The European journal of neuroscience. 15(4)
Brain derived neurotrophic factor (BDNF) has been suggested to be involved in epileptogenesis. Both pro- and antiepileptogenic effects have been reported, but the exact physiological role is still unclear. Here, we investigated the role of endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::894b856f3424f1db8fca27320adf8314
https://pubmed.ncbi.nlm.nih.gov/11886452
https://pubmed.ncbi.nlm.nih.gov/11886452