Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Eiichi TANI"'
Autor:
Tsuyoshi Matsumoto, Eiichi Tani
Publikováno v:
Current Vascular Pharmacology. 2:13-21
Subarachnoid hemorrhage (SAH)-induced cerebral vasospasm causes serious neurological morbidity and mortality mainly because of the absence of effective treatment. Therefore, we reviewed the molecular mechanisms involved in the development of the cere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f437404e2569f8ad58dca85e0b4fe8b
https://doi.org/10.2174/1570161043476492
https://doi.org/10.2174/1570161043476492
Publikováno v:
Circulation Research. 87:195-200
Abstract —Subarachnoid hemorrhage (SAH) often induces a long-term narrowing of the cerebral artery called cerebral vasospasm. Myosin light chain (MLC) in the spastic basilar artery was reported previously to be phosphorylated by Ca 2+ /calmodulin-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4427339e8afb1e588a15cccee66f6615
https://doi.org/10.1161/01.res.87.3.195
https://doi.org/10.1161/01.res.87.3.195
Publikováno v:
Cell Death & Differentiation. 7:511-520
Calphostin C-mediated apoptosis in glioma cells was reported previously to be associated with down-regulation of Bcl-2 and Bcl-xL. In this study, we report that 100 nM calphostin C also induces translocation and integration of monomeric Bax into mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f832464bece9f06edfc42516d44b622d
https://doi.org/10.1038/sj.cdd.4400682
https://doi.org/10.1038/sj.cdd.4400682
Autor:
Eiichi Tani, Masayuki Yokota, Masahiro Fukami, Ikuya Yamaura, Atsuhisa Nakano, Keizo Kaba, Tsuyoshi Matsumoto
Publikováno v:
Journal of Neurosurgery. 90:853-856
Object. Surgical or endovascular occlusion of the parent artery proximal to an aneurysm has been recommended for treatment of dissecting aneurysms of the intracranial posterior circulation. However, dissecting aneurysms may rupture even after proxima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc62528de7e16a1ff11bdb0969f5507b
https://doi.org/10.3171/jns.1999.90.5.0853
https://doi.org/10.3171/jns.1999.90.5.0853
Publikováno v:
Journal of Biological Chemistry. 274:5310-5317
Apoptosis was induced in human glioma cell lines by exposure to 100 nm calphostin C, a specific inhibitor of protein kinase C. Calphostin C-induced apoptosis was associated with synchronous down-regulation of Bcl-2 and Bcl-xL as well as activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4812d9a8d6d0add0f655f2f33345ccd6
https://doi.org/10.1074/jbc.274.9.5310
https://doi.org/10.1074/jbc.274.9.5310
Publikováno v:
FEBS Letters. 443:181-186
The proteasome inhibitors lactacystin and AcLLNal induced p53-independent apoptosis in two human glioma cell lines, and the apoptosis was accompanied by up-regulation of immunoreactive wild-type p53, p21Waf1, Mdm2, and p27Kip1. Pretreatment with cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e90c19fa674943739372a610aae930
https://doi.org/10.1016/s0014-5793(98)01709-8
https://doi.org/10.1016/s0014-5793(98)01709-8
Autor:
Ikuya Yamaura, Eiichi Tani, Isao Ozaki, Motohiko Sato, Katsuya Miyaji, Shinobu Imajoh-Ohmi, Hirokazu Fujikawa, Katsuhito Takahashi
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 19:44-52
Subarachnoid hemorrhage (SAH) often leads to a long-term narrowing of cerebral artery called vasospasm. To understand the molecular mechanisms in vasospasm, signal transduction of tyrosine kinase pathway and phosphorylation of myosin light chain (MLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79986e8e183c3f9e9c7f7a1bbe731ff
https://doi.org/10.1097/00004647-199901000-00005
https://doi.org/10.1097/00004647-199901000-00005
Publikováno v:
Surgery for Cerebral Stroke. 25:472-475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57286c56475a7bb4295a2165343f1527
https://doi.org/10.2335/scs1987.25.6_472
https://doi.org/10.2335/scs1987.25.6_472
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 16:1219-1223
We developed an antibody specific to β-amyloid precursor protein (βAPP) fragments possessing the exact amino terminus of the β-amyloid peptide and examined its induction in postischemic hippocampus. In control hippocampus, this APP fragment was li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8983100424bf3db6df05e00c75891d21
https://doi.org/10.1097/00004647-199611000-00016
https://doi.org/10.1097/00004647-199611000-00016
Publikováno v:
Journal of Neurosurgery. 83:1008-1016
✓ Calphostin C acts at the regulatory domain as a highly selective inhibitor of protein kinase C (PKC), and staurosporine acts at the catalytic domain as a nonspecific PKC inhibitor. The authors investigated the capacity of calphostin C and stauros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38b2e999b1b8ac8217b3c9c992ba692
https://doi.org/10.3171/jns.1995.83.6.1008
https://doi.org/10.3171/jns.1995.83.6.1008