Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Eiichi Sugaya"'
Autor:
Takayuki Sakurai, Jiyang O-Wang, Motoya Katsuki, Shunji Yamashita, Masafumi Tanaka, Minoru Kimura, Masahiro Sato, Kagemasa Kajiwara, Kazuki Nakao, Eiichi Sugaya, Masatoshi Tagawa, Kenji Nakamura
Publikováno v:
Genes to Cells. 6:99-106
Background Sez4 identified as a seizure-activated gene shows a similarity to the yeast REV3 that encodes a catalytic subunit of the nonessential DNA polymerase ζ which is involved in error-prone translesion synthesis. Although yeast REV3 homologues
Publikováno v:
Brain Research. 860:21-28
To elucidate the role of the large conductance calcium-activated potassium channel (BK(Ca) channel) in the production of bursting activity, which is characteristic of convulsions, effects of iberiotoxin (IbTX), a selective blocker of the BK(Ca) chann
Autor:
Shigeharu Wakana, Hiromi Ohguchi, Fumiki Naramoto, Chika Maruyama, Aiko Sugaya, Wen Jin, Norikazu Yokote, Kagemasa Kajiwara, Eiichi Sugaya, Tadashi Tsuda
Publikováno v:
Brain Research. 857:286-290
Gene mapping of the newly discovered SEZ genes (seizure-related genes) in the mouse was performed by linkage analysis. SEZ6 was on chromosome 11, SEZ12 on chromosome 16, SEZ15 on chromosome 3 and SEZ17 (PTZ17) on chromosome 18. The mouse chromosomal
Autor:
Tadashi Tsuda, Masahiro Motoki, Keiko Shimizu-Nishikawa, Noriyuki Yuyama, Aiko Sugaya, Minoru Kimura, Hideko Nagasawa, Eiichi Sugaya, Kagemasa Kajiwara
Publikováno v:
Molecular Brain Research. 47:49-58
To determine the molecular mechanism of regulation of pentylenetetrazol (PTZ)-induced calcium entry by the seizure-related gene, PTZ-17, the role of the 3'-untranslated region (3'UTR) and also interaction between 3'UTR and intracellular factors were
Autor:
Eiichi Sugaya, Keiko Shimizu-Nishikawa, Noriyuki Yuyama, Aiko Sugaya, Tadashi Tsuda, Kagemasa Kajiwara, Masahiro Motoki, Minoru Kimura
Publikováno v:
Brain and Development. 19:93-103
Doctors who learned exclusively western medicine probably understand a priori Kampo (Japanese herbal) medicine merely as a kind of folk medicine which is not so effective and only a supplementary therapy to western medicine. We have been performing e
Autor:
Eiichi Sugaya, Hideko Nagasawa, Tamiko Ookura, Minoru Kimura, Kagemasa Kajiwara, Keiko Shimizu-Nishikawa
Publikováno v:
Biochemical and Biophysical Research Communications. 222:144-148
SEZ-12 is one of the seizure-related cDNAs which was isolated by differential hybridization from primary cultured neurons from the mouse cerebral cortex with or without pentylenetetrazol (PTZ). SEZ-12 expression is transiently down-regulated in the m
Autor:
Keiko Shimizu-Nishikawa, Eiichi Sugaya, Minoru Kimura, Hideko Nagawawa, Kagemasa Kajiwara, Tamiko Ookura
Publikováno v:
Biochemical and Biophysical Research Communications. 219:795-799
To isolate seizure-related genes, we applied differential screening technique to the cDNA library which constructed from primary cultured cerebral cortical cells treated with pentylenetetrazol (PTZ). Northern blotting analysis of mRNA levels in the c
Autor:
H. Kawazura, M. Kohno, H. Tanaka, Aiko Sugaya, Yong Zhen Liu, Eiichi Sugaya, Tadashi Tsuda, K. Katoh, M. Kusai
Publikováno v:
Journal of Ethnopharmacology. 41:85-90
To elucidate the mechanism of the invigorating and antisenile action of the dried herb of Boschniakia rossica (Boschniakiae Herba), the free radical scavenging activity of its 50% ethanol extract (BR) was examined using an electron spin resonance spe
Autor:
Yoko Wakui, Susumu Iizuka, Akira Sugimoto, Kyoji Sekiguchi, Shuichi Takeda, Masaki Aburada, Atsushi Ishige, Kasuhisa Ishihara, Toshimitsu Yuzurihara, Eiichi Sugaya
Publikováno v:
Journal of Ethnopharmacology. 34:13-19
In the cobalt focus experimental epilepsy model, severe hippocampal neuron damage occurs with marked EEG changes. The effects of TJ-960, a herbal medicine formulation, were studied on neuron damage in the CA1 area of rat hippocampus. Continuous oral
Publikováno v:
Journal of Ethnopharmacology. 33:159-167
To elucidate the mechanism of anticonvulsant action of peony root and to determine the relative contributions of pure component substances, the water, water/acetone and methanol extracts of peony roots, paeoniflorin, albiflorin and pentagalloylglucos