Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Eiichi Maru"'
Publikováno v:
Brain research. 1694
Blood-brain barrier (BBB) breakdown and the subsequent exposure of the cerebral cortex to serum albumin are known to activate transforming growth factor β (TGF-β) signaling in astrocytes and to play key roles in epileptogenesis after brain injury.
Autor:
Takako Takemiya, Hiroko Sugiura, Kanato Yamagata, Eiichi Maru, Shin Yasuda, Kyoko Suzuki, Yoriko Kawakami
Publikováno v:
Prostaglandins & Other Lipid Mediators. 71:205-216
Brain cyclooxygenase-2 (COX-2), the rate-limiting enzyme in prostaglandin synthesis, is rapidly and transiently induced by convulsions in hippocampal and cortical neurons. Therefore, we examined the effects of COX-2 on the 'rapid kindling' developmen
Autor:
Eiichi, Maru, Hiroyuki, Ura
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 72(5)
Recent studies clarified a dynamic regulation of the intracellular trafficking of GABA(A) receptors and its involvement in the pathophysiology of epilepsy. GABA(A) synaptic inhibition decreased in the hippocampal CA1 area of patients with intractable
Autor:
Eiichi Maru, Hisayuki Ohata
Publikováno v:
Journal of Nippon Medical School. 64:154-162
It is reported that chronic electrical stimulation of perforant path (PP) produces mossy fiber sprouting in dentate granule cells and as a result new recurrent excitatory circuits are formed. It has been assumed that the circuits are responsible for
Publikováno v:
Brain research. 1352
Electroencephalographic (EEG) seizures and behavioral convulsions begin to appear spontaneously a few weeks after chemoconvulsant-induced status epilepticus (SE) and thereafter become more intense. This indicates the progressive development of a long
Publikováno v:
Neuroscience research. 66(2)
A novel antiepileptic drug, levetiracetam, strongly suppresses the development of kindling, although the mechanisms by which it does so are still unknown. Kindling-induced synaptic potentiation (KIP) is considered to play an important role in the dev
Publikováno v:
Epilepsia. 43
Summary: Purpose: We review what is currently known about functional and morphologic plasticity of hippocampal neuronal circuits in animal epilepsy models. Results: Perforant-path kindling has been shown to enhance excitatory synaptic transmission in
Publikováno v:
Anesthesia and analgesia. 90(5)
Lidocaine induces electroencephalographic seizures and generalized convulsions at large doses. It is possible that epileptic patients are more susceptible to the proconvulsant effect of lidocaine. Using a kindling model of epilepsy, we examined wheth
Autor:
Takashi Watanabe, Nobuaki Hori, Takao Shimizu, Keiichi Watanabe, Katsuhiko Ogata, Tomokatsu Hori, Makoto Nishiyama, Eiichi Maru
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461371717
Long-term potentiation (LTP) of synaptic transmission is a well defined form of neuronal plasticity. The induction of LTP at perforant path-dentate granule cell and Schaffer collateral-CA1 pyramidal cell synapses of the hippocampus is known to requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a56cf64b2a12ff60aa5a0c78098d7ee
https://doi.org/10.1007/978-1-4615-4793-8_7
https://doi.org/10.1007/978-1-4615-4793-8_7
Autor:
Eiichi Maru
Publikováno v:
Nihon Ika Daigaku zasshi. 58(1)