Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Eiichi Kumamoto"'
Autor:
Eiichi Kumamoto
Publikováno v:
Encyclopedia, Vol 2, Iss 4, Pp 1902-1934 (2022)
The action potential (AP) conduction in nerve fibers plays a crucial role in transmitting nociceptive information from the periphery to the cerebral cortex. Nerve AP conduction inhibition possibly results in analgesia. It is well-known that many anal
Externí odkaz:
https://doaj.org/article/3a80b61b1c434fd282a904d9f028a69b
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 1, Pp 100155- (2022)
Background: Many of plant-derived compounds inhibiting nerve conduction enhance glutamatergic spontaneous excitatory transmission by activating transient receptor potential (TRP) channels in spinal substantia gelatinosa (SG) neurons that play a cruci
Externí odkaz:
https://doaj.org/article/56c7ad4611a84f69a07753915c4d4a32
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 145-151 (2017)
Although the endocrine disruptor bisphenol A (BPA) is reported to inhibit nerve conduction, the underlying mechanisms are unclear. Therefore, in the present study, we examined the effect of BPA on compound action potentials (CAPs) recorded from the f
Externí odkaz:
https://doaj.org/article/d0863258cd734fbb9be38b5f414e611a
Autor:
Eiichi Kumamoto
Publikováno v:
Pharmaceuticals, Vol 13, Iss 4, p 62 (2020)
Nociceptive information is transmitted from the periphery to the cerebral cortex mainly by action potential (AP) conduction in nerve fibers and chemical transmission at synapses. Although this nociceptive transmission is largely inhibited at synapses
Externí odkaz:
https://doaj.org/article/3d6a0d1f2b424483b416d3ebeb42f4a5
Publikováno v:
Cells, Vol 3, Iss 2, Pp 331-362 (2014)
The spinal substantia gelatinosa (SG) plays a pivotal role in modulating nociceptive transmission through dorsal root ganglion (DRG) neurons from the periphery. TRP channels such as TRPV1 and TRPA1 channels expressed in the SG are involved in the reg
Externí odkaz:
https://doaj.org/article/6ae6287c2bc745c4b806b93e89f8e501
Autor:
Eiichi Kumamoto
Publikováno v:
Pharmaceuticals, Vol 12, Iss 3, p 136 (2019)
Much evidence indicates that hypothalamus-derived neuropeptides, oxytocin, orexins A and B, inhibit nociceptive transmission in the rat spinal dorsal horn. In order to unveil cellular mechanisms for this antinociception, the effects of the neuropepti
Externí odkaz:
https://doaj.org/article/e6bf275f45c04565892fe8661e5c8919
Publikováno v:
Pharmaceuticals, Vol 4, Iss 2, Pp 343-365 (2011)
Opioids inhibit glutamatergic excitatory transmission from the periphery by activating G-protein coupled opioid receptors in the central terminals of primary-afferent neurons in the spinal substantia gelatinosa, resulting in antinociception. Opioid r
Externí odkaz:
https://doaj.org/article/35e5bc6c73f54343a80f60d5d25ae675
Autor:
Eiichi Kumamoto, Tsugumi Fujita
Publikováno v:
Pharmaceuticals, Vol 9, Iss 3, p 46 (2016)
Activation of TRPV1, TRPA1 or TRPM8 channel expressed in the central terminal of dorsal root ganglion (DRG) neuron increases the spontaneous release of l-glutamate onto spinal dorsal horn lamina II (substantia gelatinosa; SG) neurons which play a piv
Externí odkaz:
https://doaj.org/article/570a94fd69a04aebb8b750312de7b223
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 1, Pp 100155-(2022)
Background: Many of plant-derived compounds inhibiting nerve conduction enhance glutamatergic spontaneous excitatory transmission by activating transient receptor potential (TRP) channels in spinal substantia gelatinosa (SG) neurons that play a cruci
Autor:
Tsugumi Fujita, Eiichi Kumamoto
Publikováno v:
PAIN RESEARCH. 34:291-303