Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Eiichi Akaho"'
Autor:
Eiichi Akaho
Publikováno v:
International Journal of Applied Pharmaceutics. :122-131
Objective: Over the last 30 y cancer epigenetics research has grown extensively. It is note-worthy to recognize that epigenetic misregulation could substantiate the development of cancer and we need to continue to look for anti-neoplastic epi-drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c1a6d64fd4efa805830f8b4b72a24b5
https://doi.org/10.22159/ijap.2021v13i5.42275
https://doi.org/10.22159/ijap.2021v13i5.42275
Autor:
Eiichi Akaho
Gravity, antigravity, and gravitational shielding are all interconnected topics. However, we find very few papers that address this interconnected topic from a global perspective. Gravity and gravity-related topics are one of the most fascinating are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a415f942b48b8fa4e7a9abdc9f71ea1
https://doi.org/10.9734/bpi/castr/v14/11281d
https://doi.org/10.9734/bpi/castr/v14/11281d
Publikováno v:
Bioinformation
Different classes of compounds were investigated for their binding affinities into different protein tyrosine kinases (PTKs) employing a novel flexible ligand docking approach by using AutoDock 3.05 and 4. These compounds include many flavin analogs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e8b1625a202b0993ce5eafa56b3db0
https://doi.org/10.6026/97320630005368
https://doi.org/10.6026/97320630005368
Autor:
Yutaka Kawashima, Takehiro Yamagishi, Hamed I. Ali, Tomohisa Nagamatsu, Eiichi Akaho, Keiichiro Tomita, Hisao Ikeya, Munetaka Kunishima
Publikováno v:
European Journal of Medicinal Chemistry. 43:1376-1389
Various analogs of flavins, 5-deazaflavins, and flavin-5-oxides were docked into the binding site of protein tyrosine kinase pp60 c-src , and some of them were assayed for their potential antitumor and PKC (protein kinase C) inhibitory activities in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d790355ee2652ce6035b079db1881d
https://doi.org/10.1016/j.ejmech.2007.10.011
https://doi.org/10.1016/j.ejmech.2007.10.011
Autor:
Shinji Miura, Eiichi Akaho, Hiroyuki Hayakawa, Hamed I. Ali, Hiroto Kambara, Hisao Ikeya, Fumio Yoneda, Yutaka Kawashima, Tomohisa Nagamatsu, Keiichiro Tomita, Takehiro Yamagishi, Noriyuki Ashida
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:242-256
Novel 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides were prepared as a new class of antitumor agents and showed significant antitumor activities against NCI-H 460, HCT 116, A 431, CCRF-HSB-2, andKB cell lines. In vivo investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a66df66ec8706a5459b29d6dbbfb19
https://doi.org/10.1016/j.bmc.2006.09.063
https://doi.org/10.1016/j.bmc.2006.09.063
Publikováno v:
Il Farmaco. 60:497-506
A series of 3-(substituted-benzylidene)-1, 3-dihydro-indolin-2-thione derivatives were synthesized as modified congeners of 3-(substituted-benzylidene)-1, 3-dihydro-indolin-2-one series. All the synthesized compounds were examined for their in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7ae4f4902cb03a1e56ee9c97d0b703
https://doi.org/10.1016/j.farmac.2005.01.015
https://doi.org/10.1016/j.farmac.2005.01.015
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 31:869-882
The objective of this mini-review is to examine collaborative prescribing between pharmacists and physicians as a means of enhancing the professional status of pharmacists. It considers the history of such collaboration, the current status of healthc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45b5e6921a9916c0a882c2c3d2538f5b
https://doi.org/10.5649/jjphcs.31.869
https://doi.org/10.5649/jjphcs.31.869
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 30:505-510
There are several types of community pharmacies in the United States. The most common are independents, chains, and supermarket pharmacies. There are pharmacies that specialize in home healthcare supplies/devices, compounding, and infusions. Currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d92f1127a6c110eccf3030d0449f046
https://doi.org/10.5649/jjphcs.30.505
https://doi.org/10.5649/jjphcs.30.505
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 18:485-490
Several indole esters were tested as inhibitors of tyrosine kinase p60(c-Src). Compound (4) was found fairly active against the enzyme with IC50 = 1.34 microM. DOCK methodology was used to asses our inhibitors for their inhibitory potency against tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7511d3dea977a7a7212cfd16440eb636
https://doi.org/10.1080/14756360310001612211
https://doi.org/10.1080/14756360310001612211