Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Eiichi, Akahoshi"'
Autor:
Ikumi Nakashima, Shoji Saito, Eiichi Akahoshi, Shigeki Yagyu, Mitsuko Sugano-Ishihara, Yozo Nakazawa
Publikováno v:
Biochemical and Biophysical Research Communications. 635:144-153
Breast cancer is a complex heterogeneous disease with unique molecular subtypes, which limits the development of optimized treatment strategies for each subtype. Cancer gene therapy and potential therapeutics for advanced/refractory cancers can be pr
Autor:
Shoji Saito, Mitsuko Ishihara-Sugano, Eiichi Akahoshi, Yozo Nakazawa, Ikumi Nakashima, Aiko Hasegawa, Shigeki Yagyu
Publikováno v:
Blood. 136:21-22
Introduction : Treatment options for relapsed T cell leukemia are limited, and the prognosis remains dismal. Therefore, the development of new therapies is crucial. A liposomal delivery system has been increasingly recognized as a promising strategy
Autor:
Junko Tokumoto, Michiko Saito, Daichi Nagahara, Mitsuko Ishihara-Sugano, Nobuhiko Hoshi, Megumi Danjo, Eiichi Akahoshi, Takashi Tanida, Hiroshi Kitagawa, Shigehisa Kawata, Ken Tasaka, Youhei Mantani, Mitsuhiro Kawata, Toshifumi Yokoyama, Yoshiaki Tabuchi
Publikováno v:
Journal of Applied Toxicology. 34:117-126
Fetal exposure to dioxins and related compounds is known to disrupt normal development of the midbrain dopaminergic system, which regulates behavior, cognition and emotion. The toxicity of these chemicals is mediated mainly by aryl hydrocarbon recept
Autor:
Seiko Yoshimura, Noriyuki Kurita, Saeko Uruno, Kazuya Sashino, Satoshi Miyagi, Kyoshiro Murata, Mitsuko Ishihara-Sugano, Eiichi Akahoshi, Satoshi Itoh, Satoshi Sawamura
Aryl hydrocarbon receptor (AhR) plays critical roles in cell differentiation, and its mechanism is controlled by exogenous and endogenous ligands. However, structures of AhR and its complex with ligand have not been determined by experimental structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e628ba0cee648f5153117d3353c54715
Publikováno v:
Soil Science and Plant Nutrition. 49:379-385
Eight independent transgenic lines of Arabidopsis thaliana were generated carrying homozygous insertions of the cauliflower mosaic virus 35S RNA promoter driving antisense MT2a ORF or the heat shock-protein 81-1 promoter driving sense MT2a ORF. Six t
Autor:
Mitsuo Chino, Takuji Ohyama, Toru Fujiwara, Eiichi Akahoshi, Keishiro Takahashi, Hiroaki Hayashi, Taro Ikarashi, Tatsuya Horiguchi, Katsuhiko Mineta
Publikováno v:
Soil Science and Plant Nutrition. 46:189-197
Accumulation of mRNA for MT2a, a metallothionein of Arabidopsis thaliana, is known to be upregulated by excess copper (Cu). We compared the localization of the promoter activity of the MT2a gene and the accumulation site(s) of CU in the roots of tran
Autor:
Takashi, Tanida, Ken, Tasaka, Eiichi, Akahoshi, Mitsuko, Ishihara-Sugano, Michiko, Saito, Shigehisa, Kawata, Megumi, Danjo, Junko, Tokumoto, Youhei, Mantani, Daichi, Nagahara, Yoshiaki, Tabuchi, Toshifumi, Yokoyama, Hiroshi, Kitagawa, Mitsuhiro, Kawata, Nobuhiko, Hoshi
Publikováno v:
Journal of applied toxicology : JAT. 34(2)
Fetal exposure to dioxins and related compounds is known to disrupt normal development of the midbrain dopaminergic system, which regulates behavior, cognition and emotion. The toxicity of these chemicals is mediated mainly by aryl hydrocarbon recept
Publikováno v:
Toxicology mechanisms and methods. 22(6)
Tyrosine hydroxylase (TH) assay is a novel bioassay for screening aryl hydrocarbon receptor (AhR)-active compounds with diverse toxicities. The TH assay employs reporter genes to evaluate TH promoter activity, which is linked to dopamine synthesis an
Publikováno v:
Environmental Health, Vol 8, Iss 1, p 24 (2009)
Environmental Health
Environmental Health
BackgroundDioxins and related compounds are suspected of causing neurological disruption. Epidemiological studies indicated that exposure to these compounds caused neurodevelopmental disturbances such as learning disability and attention deficit hype
Publikováno v:
Environmental Health
Environmental Health, Vol 5, Iss 1, p 24 (2006)
Environmental Health, Vol 5, Iss 1, p 24 (2006)
Background Dioxins and related compounds are suspected of causing neurological disruption in human and experimental animal offspring following perinatal exposure during development and growth. The molecular mechanism(s) of the actions in the brain, h