Výsledky vyhledávání - "Eid S. Alshammari"

Akademický článek

ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Amjad A. Aljagthmi, Andrew J. Stacy, Mike Bottomley, H. Nicholas Shamma, Madhavi P. Kadakia, Weiwen Long

Publikováno v: BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)

Abstract Background p63, a member of the p53 gene family, is an important regulator for epithelial tissue growth and development. ∆Np63α is the main isoform of p63 and highly expressed in Non-melanoma skin cancer (NMSC). Extracellular signal-regul

Externí odkaz: https://doaj.org/article/b91dda3109c34727af0adb4d89f0e177

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Additional file 3 of ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, H. Nicholas Shamma, Kadakia, Madhavi P., Weiwen Long

Additional file 3: Figure S3. Full-length Western blots for Fig. 4a.

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Additional file 6 of ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, H. Nicholas Shamma, Kadakia, Madhavi P., Weiwen Long

Additional file 6: Figure S6. Full-length Western blots for Fig. 7b and c.

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Additional file 4 of ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, H. Nicholas Shamma, Kadakia, Madhavi P., Weiwen Long

Additional file 4: Figure S4. Full-length Western blots for Fig. 5a. In each image, lane 1 corresponds to the lysate of the NSC and CDH expression, lane 2 to sip63 and CDH, and lane 3 to sip63 and CDH-ERK3.

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Additional file 1 of ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, H. Nicholas Shamma, Kadakia, Madhavi P., Weiwen Long

Additional file 1: Figure S1. Representative images of Normal, AK, SCC and BCC skin tissues after Haemotoxylin and Eosin (H&E) staining.

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Additional file 7 of ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, H. Nicholas Shamma, Kadakia, Madhavi P., Weiwen Long

Additional file 7: Table S1. Descriptive statistics for ΔNp63α and ERK3 co-immunofluorescence staining in normal skin and non-melanoma cancer tissue microarrays. Normal skin (N = 53), cutaneous squamous cell carcinoma (SCC) (N = 59), basal cell car

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Additional file 9 of ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, H. Nicholas Shamma, Kadakia, Madhavi P., Weiwen Long

Additional file 9: Table S3. Correlation for the mean fluorescence intensity of ΔNp63α and ERK3 in each skin tissue type.

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Additional file 2 of ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers

Autor: Eid S. Alshammari, Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, H. Nicholas Shamma, Kadakia, Madhavi P., Weiwen Long

Additional file 2: Figure S2. Full-length Western blots for Fig. 3c.

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ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in Non-Melanoma Skin Cancers

Autor: Andrew J. Stacy, Mike Bottomley, H. Nicholas Shamma, Madhavi P. Kadakia, Eid S. Alshammari, Amjad Ahmed Aljagthmi, Weiwen Long

Publikováno v: BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)

Background p63, a member of the p53 gene family, is an important regulator for epithelial tissue growth and development. ∆Np63α is the main isoform of p63 and highly expressed in Non-melanoma skin cancer (NMSC). Extracellular signal-regulated kina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bffba543eb26dab8f7c843d85c70064
https://doi.org/10.21203/rs.2.23512/v1

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