Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Eid Clark Norman"'
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Synthesis of a radioiodinated park nucleotide analog: a new tool for antibacterial screen development
Autor: Chuyn-Yeh Ernie Wu, John M. Richardson, Eid Clark Norman, Mohammad Zia-Ebrahimi, Yao Raymond Che-Fong, Karen Cox, Michael J. Nesler
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 41:705-716
The Park nucleotide is an important biological building block used in the construction of bacterial cell walls. Herein, we describe the synthesis of a radiolabeled Park nucleotide analog, p-iodophenoxyacyl-Ala-(d)-iso-Glu-Lys-(d)-Ala-(d)-Ala-OH-[123I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53f45f230d28ecfbf51bec82474d197d
https://doi.org/10.1002/(sici)1099-1344(1998080)41:8<705::aid-jlcr119>3.0.co
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3
Synthesis of new 3-thiosubstituted carbacephem antibiotics and their activity against penicillin resistant Streptococcus pneumoniae
Autor: Eid Clark Norman, J. E. Flokowitsch, David A. Preston, Mohammad Zia-Ebrahimi, Larry C. Blaszczak, Stephen A. Hitchcock, G. Stuart Gregory, Michael J. Nesler, George W. Huffman, Daniel Ray Mayhugh
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 7:2261-2264
The synthesis of a series of 3-thiosubstituted carbacephem derivatives is described. The compounds were assayed against penicillin susceptible, intermediate and resistant strains of Streptococcus pneumoniae. Several analogs displayed potent in vitro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::017c606fd98ea7bd7bf42c93451cf79d
https://doi.org/10.1016/s0960-894x(97)00412-5
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4
Design, syntheses and potentiating activities against methicillin resistant Staphylococcus aureus of cyclic analogs of LY301621
Autor: Loncharich Richard James, Thalia I. Nicas, Jonathan W. Paschal, Deborah L. Mullen, Eid Clark Norman
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 7:2087-2092
Previous SAR studies of the diastereomers of LY301621 suggested the importance of a β-turn conformation for biological activity. In the present study, cyclic analogs were designed and synthesized that possess Type II and II' β-turns. Their biologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::683288110d53ce72c3a9c479c874e0cc
https://doi.org/10.1016/s0960-894x(97)00371-5
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Plný text Recenzováno Digitální knihovna AV ČR
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