Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Eicher JD"'
Autor:
Johnson, JO, Chia, R, Miller, DE, Li, R, Kumaran, R, Abramzon, Y, Alahmady, N, Renton, AE, Topp, SD, Gibbs, JR, Cookson, MR, Sabir, MS, Dalgard, CL, Troakes, C, Jones, AR, Shatunov, A, Iacoangeli, A, Al Khleifat, A, Ticozzi, N, Silani, V, Gellera, C, Blair, IP, Dobson-Stone, C, Kwok, JB, Bonkowski, ES, Palvadeau, R, Tienari, PJ, Morrison, KE, Shaw, PJ, Al-Chalabi, A, Brown, RH, Calvo, A, Mora, G, Al-Saif, H, Gotkine, M, Leigh, F, Chang, IJ, Perlman, SJ, Glass, I, Scott, AI, Shaw, CE, Basak, AN, Landers, JE, Chiò, A, Crawford, TO, Smith, BN, Traynor, BJ, Fallini, C, Gkazi, AS, Scotter, EL, Kenna, KP, Keagle, P, Tiloca, C, Vance, C, Colombrita, C, King, A, Pensato, V, Castellotti, B, Baas, F, ten Asbroek, ALMA, McKenna-Yasek, D, McLaughlin, RL, Polak, M, Asress, S, Esteban-Pérez, J, Stevic, Z, D’Alfonso, S, Mazzini, L, Comi, GP, Del Bo, R, Ceroni, M, Gagliardi, S, Querin, G, Bertolin, C, van Rheenen, W, Rademakers, R, van Blitterswijk, M, Lauria, G, Duga, S, Corti, S, Cereda, C, Corrado, L, Sorarù, G, Williams, KL, Nicholson, GA, Leblond-Manry, C, Rouleau, GA, Hardiman, O, Veldink, JH, van den Berg, LH, Pall, H, Turner, MR, Talbot, K, Taroni, F, García-Redondo, A, Wu, Z, Glass, JD, Ratti, A, Adeleye, A, Soltis, AR, Alba, C, Viollet, C, Bacikova, D, Hupalo, DN, Sukumar, G, Pollard, HB, Wilkerson, MD, Martinez, EM, Ahmed, S, Arepalli, S, Baloh, RH, Bowser, R, Brady, CB, Brice, A, Broach, J, Campbell, RH, Camu, W, Cooper-Knock, J, Ding, J, Drepper, C, Drory, VE, Dunckley, TL, Eicher, JD, England, BK, Faghri, F, Feldman, E, Floeter, MK, Fratta, P, Geiger, JT, Gerhard, G, Gibson, SB, Hardy, J, Harms, MB, Heiman-Patterson, TD, Hernandez, DG, Jansson, L, Kirby, J, Kowall, NW, Laaksovirta, H, Landeck, N, Landi, F, Le Ber, I, Lumbroso, S, MacGowan, DJL, Maragakis, NJ, Mouzat, K, Murphy, NA, Myllykangas, L, Nalls, MA, Orrell, RW, Ostrow, LW, Pamphlett, R, Pickering-Brown, S, Pioro, EP, Pletnikova, O, Pliner, HA, Pulst, SM, Ravits, JM, Rivera, A, Robberecht, W, Rogaeva, E, Rollinson, S, Rothstein, JD, Scholz, SW, Sendtner, M, Sidle, KC, Simmons, Z, Singleton, AB, Smith, N, Stone, DJ, Troncoso, JC, Valori, M, Van Damme, P, Van Deerlin, VM, Van Den Bosch, L, Zinman, L, Angelocola, SM, Ausiello, FP, Barberis, M, Bartolomei, I, Battistini, S, Bersano, E, Bisogni, G, Borghero, G, Brunetti, M, Cabona, C, Canale, F, Canosa, A, Cantisani, TA, Capasso, M, Caponnetto, C, Cardinali, P, Carrera, P, Casale, F, Colletti, T, Conforti, FL, Conte, A, Conti, E, Corbo, M, Cuccu, S, Dalla Bella, E, D’Errico, E, DeMarco, G, Dubbioso, R, Ferrarese, C, Ferraro, PM, Filippi, M, Fini, N, Floris, G, Fuda, G, Gallone, S, Gianferrari, G, Giannini, F, Grassano, M, Greco, L, Iazzolino, B, Introna, A, La Bella, V, Lattante, S, Liguori, R, Logroscino, G, Logullo, FO, Lunetta, C, Mandich, P, Mandrioli, J, Manera, U, Manganelli, F, Marangi, G, Marinou, K, Marrosu, MG, Martinelli, I, Messina, S, Moglia, C, Mosca, L, Murru, MR, Origone, P, Passaniti, C, Petrelli, C, Petrucci, A, Pozzi, S, Pugliatti, M, Quattrini, A, Ricci, C, Riolo, G, Riva, N, Russo, M, Sabatelli, M, Salamone, P, Salivetto, M, Salvi, F, Santarelli, M, Sbaiz, L, Sideri, R, Simone, I, Simonini, C, Spataro, R, Tanel, R, Tedeschi, G, Ticca, A, Torriello, A, Tranquilli, S, Tremolizzo, L, Trojsi, F, Vasta, R, Vacchiano, V, Vita, G, Volanti, P, Zollino, M, Zucchi, E
Publikováno v:
ITALSGEN Consortium, International ALS Genomics Consortium, American Genome Center & FALS Sequencing Consortium 2021, ' Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis ', JAMA Neurology, vol. 78, no. 10, pp. 1236-1248 . https://doi.org/10.1001/jamaneurol.2021.2598
JAMA Neurology, 78(10), 1236-1248. AMER MEDICAL ASSOC
JAMA Neurology
Johnson, J O, Chia, R, Miller, D E, Li, R, Kumaran, R, Abramzon, Y, Alahmady, N, Renton, A E, Topp, S D, Gibbs, J R, Cookson, M R, Sabir, M S, Dalgard, C L, Troakes, C, Jones, A R, Shatunov, A, Iacoangeli, A, Al Khleifat, A, Ticozzi, N, Silani, V, Gellera, C, Blair, I P, Dobson-Stone, C, Kwok, J B, Bonkowski, E S, Palvadeau, R, Tienari, P J, Morrison, K E, Shaw, P J, Al-Chalabi, A, Brown, R H, Calvo, A, Mora, G, Al-Saif, H, Gotkine, M, Leigh, F, Chang, I J, Perlman, S J, Glass, I, Scott, A I, Shaw, C E, Basak, A N, Landers, J E, Chiò, A, Crawford, T O, Smith, B N, Traynor, B J, Smith, B N, Ticozzi, N, Fallini, C, Gkazi, A S, Topp, S D, Scotter, E L, Kenna, K P, Keagle, P, Tiloca, C, Vance, C, Troakes, C, Colombrita, C, King, A, Pensato, V, Castellotti, B, Baas, F, Ten Asbroek, A L M A, McKenna-Yasek, D, McLaughlin, R L, Polak, M, Asress, S, Esteban-Pérez, J, Stevic, Z, D'Alfonso, S, Mazzini, L, Comi, G P, Del Bo, R, Ceroni, M, Gagliardi, S, Querin, G, Bertolin, C, Van Rheenen, W, Rademakers, R, Van Blitterswijk, M, Lauria, G, Duga, S, Corti, S, Cereda, C, Corrado, L, Sorarù, G, Williams, K L, Nicholson, G A, Blair, I P, Leblond-Manry, C, Rouleau, G A, Hardiman, O, Morrison, K E, Veldink, J H, Van Den Berg, L H, Al-Chalabi, A, Pall, H, Shaw, P J, Turner, M R, Talbot, K, Taroni, F, García-Redondo, A, Wu, Z, Glass, J D, Gellera, C, Ratti, A, Brown, R H, Silani, V, Shaw, C E, Landers, J E, Dalgard, C L, Adeleye, A, Soltis, A R, Alba, C, Viollet, C, Bacikova, D, Hupalo, D N, Sukumar, G, Pollard, H B, Wilkerson, M D, Martinez, E M G, Abramzon, Y, Ahmed, S, Arepalli, S, Baloh, R H, Bowser, R, Brady, C B, Brice, A, Broach, J, Campbell, R H, Camu, W, Chia, R, Cooper-Knock, J, Ding, J, Drepper, C, Drory, V E, Dunckley, T L, Eicher, J D, England, B K, Faghri, F, Feldman, E, Floeter, M K, Fratta, P, Geiger, J T, Gerhard, G, Gibbs, J R, Gibson, S B, Glass, J D, Hardy, J, Harms, M B, Heiman-Patterson, T D, Hernandez, D G, Jansson, L, Kirby, J, Kowall, N W, Laaksovirta, H, Landeck, N, Landi, F, Le Ber, I, Lumbroso, S, Macgowan, D J L, Maragakis, N J, Mora, G, Mouzat, K, Murphy, N A, Myllykangas, L, Nalls, M A, Orrell, R W, Ostrow, L W, Pamphlett, R, Pickering-Brown, S, Pioro, E P, Pletnikova, O, Pliner, H A, Pulst, S M, Ravits, J M, Renton, A E, Rivera, A, Robberecht, W, Rogaeva, E, Rollinson, S, Rothstein, J D, Scholz, S W, Sendtner, M, Shaw, P J, Sidle, K C, Simmons, Z, Singleton, A B, Smith, N, Stone, D J, Tienari, P J, Troncoso, J C, Valori, M, Van Damme, P, Van Deerlin, V M, Van Den Bosch, L, Zinman, L, Landers, J E, Chiò, A, Traynor, B J, Angelocola, S M, Ausiello, F P, Barberis, M, Bartolomei, I, Battistini, S, Bersano, E, Bisogni, G, Borghero, G, Brunetti, M, Cabona, C, Calvo, A, Canale, F, Canosa, A, Cantisani, T A, Capasso, M, Caponnetto, C, Cardinali, P, Carrera, P, Casale, F, Chiò, A, Colletti, T, Conforti, F L, Conte, A, Conti, E, Corbo, M, Cuccu, S, Dalla Bella, E, D'Errico, E, Demarco, G, Dubbioso, R, Ferrarese, C, Ferraro, P M, Filippi, M, Fini, N, Floris, G, Fuda, G, Gallone, S, Gianferrari, G, Giannini, F, Grassano, M, Greco, L, Iazzolino, B, Introna, A, La Bella, V, Lattante, S, Lauria, G, Liguori, R, Logroscino, G, Logullo, F O, Lunetta, C, Mandich, P, Mandrioli, J, Manera, U, Manganelli, F, Marangi, G, Marinou, K, Marrosu, M G, Martinelli, I, Messina, S, Moglia, C, Mora, G, Mosca, L, Murru, M R, Origone, P, Passaniti, C, Petrelli, C, Petrucci, A, Pozzi, S, Pugliatti, M, Quattrini, A, Ricci, C, Riolo, G, Riva, N, Russo, M, Sabatelli, M, Salamone, P, Salivetto, M, Salvi, F, Santarelli, M, Sbaiz, L, Sideri, R, Simone, I, Simonini, C, Spataro, R, Tanel, R, Tedeschi, G, Ticca, A, Torriello, A, Tranquilli, S, Tremolizzo, L, Trojsi, F, Vasta, R, Vacchiano, V, Vita, G, Volanti, P, Zollino, M & Zucchi, E 2021, ' Association of variants in the SPTLC1 gene with juvenile amyotrophic lateral sclerosis ', JAMA Neurology, vol. 78, no. 10, pp. 1236-1248 . https://doi.org/10.1001/jamaneurol.2021.2598
JAMA Neurology, 78(10), 1236-1248. American Medical Association
JAMA Neurology, 78(10), 1236-1248. AMER MEDICAL ASSOC
JAMA Neurology
Johnson, J O, Chia, R, Miller, D E, Li, R, Kumaran, R, Abramzon, Y, Alahmady, N, Renton, A E, Topp, S D, Gibbs, J R, Cookson, M R, Sabir, M S, Dalgard, C L, Troakes, C, Jones, A R, Shatunov, A, Iacoangeli, A, Al Khleifat, A, Ticozzi, N, Silani, V, Gellera, C, Blair, I P, Dobson-Stone, C, Kwok, J B, Bonkowski, E S, Palvadeau, R, Tienari, P J, Morrison, K E, Shaw, P J, Al-Chalabi, A, Brown, R H, Calvo, A, Mora, G, Al-Saif, H, Gotkine, M, Leigh, F, Chang, I J, Perlman, S J, Glass, I, Scott, A I, Shaw, C E, Basak, A N, Landers, J E, Chiò, A, Crawford, T O, Smith, B N, Traynor, B J, Smith, B N, Ticozzi, N, Fallini, C, Gkazi, A S, Topp, S D, Scotter, E L, Kenna, K P, Keagle, P, Tiloca, C, Vance, C, Troakes, C, Colombrita, C, King, A, Pensato, V, Castellotti, B, Baas, F, Ten Asbroek, A L M A, McKenna-Yasek, D, McLaughlin, R L, Polak, M, Asress, S, Esteban-Pérez, J, Stevic, Z, D'Alfonso, S, Mazzini, L, Comi, G P, Del Bo, R, Ceroni, M, Gagliardi, S, Querin, G, Bertolin, C, Van Rheenen, W, Rademakers, R, Van Blitterswijk, M, Lauria, G, Duga, S, Corti, S, Cereda, C, Corrado, L, Sorarù, G, Williams, K L, Nicholson, G A, Blair, I P, Leblond-Manry, C, Rouleau, G A, Hardiman, O, Morrison, K E, Veldink, J H, Van Den Berg, L H, Al-Chalabi, A, Pall, H, Shaw, P J, Turner, M R, Talbot, K, Taroni, F, García-Redondo, A, Wu, Z, Glass, J D, Gellera, C, Ratti, A, Brown, R H, Silani, V, Shaw, C E, Landers, J E, Dalgard, C L, Adeleye, A, Soltis, A R, Alba, C, Viollet, C, Bacikova, D, Hupalo, D N, Sukumar, G, Pollard, H B, Wilkerson, M D, Martinez, E M G, Abramzon, Y, Ahmed, S, Arepalli, S, Baloh, R H, Bowser, R, Brady, C B, Brice, A, Broach, J, Campbell, R H, Camu, W, Chia, R, Cooper-Knock, J, Ding, J, Drepper, C, Drory, V E, Dunckley, T L, Eicher, J D, England, B K, Faghri, F, Feldman, E, Floeter, M K, Fratta, P, Geiger, J T, Gerhard, G, Gibbs, J R, Gibson, S B, Glass, J D, Hardy, J, Harms, M B, Heiman-Patterson, T D, Hernandez, D G, Jansson, L, Kirby, J, Kowall, N W, Laaksovirta, H, Landeck, N, Landi, F, Le Ber, I, Lumbroso, S, Macgowan, D J L, Maragakis, N J, Mora, G, Mouzat, K, Murphy, N A, Myllykangas, L, Nalls, M A, Orrell, R W, Ostrow, L W, Pamphlett, R, Pickering-Brown, S, Pioro, E P, Pletnikova, O, Pliner, H A, Pulst, S M, Ravits, J M, Renton, A E, Rivera, A, Robberecht, W, Rogaeva, E, Rollinson, S, Rothstein, J D, Scholz, S W, Sendtner, M, Shaw, P J, Sidle, K C, Simmons, Z, Singleton, A B, Smith, N, Stone, D J, Tienari, P J, Troncoso, J C, Valori, M, Van Damme, P, Van Deerlin, V M, Van Den Bosch, L, Zinman, L, Landers, J E, Chiò, A, Traynor, B J, Angelocola, S M, Ausiello, F P, Barberis, M, Bartolomei, I, Battistini, S, Bersano, E, Bisogni, G, Borghero, G, Brunetti, M, Cabona, C, Calvo, A, Canale, F, Canosa, A, Cantisani, T A, Capasso, M, Caponnetto, C, Cardinali, P, Carrera, P, Casale, F, Chiò, A, Colletti, T, Conforti, F L, Conte, A, Conti, E, Corbo, M, Cuccu, S, Dalla Bella, E, D'Errico, E, Demarco, G, Dubbioso, R, Ferrarese, C, Ferraro, P M, Filippi, M, Fini, N, Floris, G, Fuda, G, Gallone, S, Gianferrari, G, Giannini, F, Grassano, M, Greco, L, Iazzolino, B, Introna, A, La Bella, V, Lattante, S, Lauria, G, Liguori, R, Logroscino, G, Logullo, F O, Lunetta, C, Mandich, P, Mandrioli, J, Manera, U, Manganelli, F, Marangi, G, Marinou, K, Marrosu, M G, Martinelli, I, Messina, S, Moglia, C, Mora, G, Mosca, L, Murru, M R, Origone, P, Passaniti, C, Petrelli, C, Petrucci, A, Pozzi, S, Pugliatti, M, Quattrini, A, Ricci, C, Riolo, G, Riva, N, Russo, M, Sabatelli, M, Salamone, P, Salivetto, M, Salvi, F, Santarelli, M, Sbaiz, L, Sideri, R, Simone, I, Simonini, C, Spataro, R, Tanel, R, Tedeschi, G, Ticca, A, Torriello, A, Tranquilli, S, Tremolizzo, L, Trojsi, F, Vasta, R, Vacchiano, V, Vita, G, Volanti, P, Zollino, M & Zucchi, E 2021, ' Association of variants in the SPTLC1 gene with juvenile amyotrophic lateral sclerosis ', JAMA Neurology, vol. 78, no. 10, pp. 1236-1248 . https://doi.org/10.1001/jamaneurol.2021.2598
JAMA Neurology, 78(10), 1236-1248. American Medical Association
Key Points Question What genetic variants are associated with juvenile amyotrophic lateral sclerosis (ALS)? Findings In this family-based genetic study, exome sequencing was performed in 3 patients diagnosed with juvenile ALS and failure to thrive; t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10862114c06ef9a5b843bbe1b0efa405
https://hdl.handle.net/11585/852152
https://hdl.handle.net/11585/852152
Autor:
de Vries, PS, Sabater-Lleal, M, Huffman, JE, Marten, J, Song, C, Pankratz, N, Bartz, TM, de Haan, HG, Delgado, GE, Eicher, JD, Martinez-Perez, A, Ward-Caviness, CK, Brody, JA, Chen, MH, de Maat, MPM, Franberg, M, Gill, D, Kleber, ME, Rivadeneira, F, Soria, JM, Tang, WH, Tofler, GH, Uitterlinden, AG, Vlieg, AV, Seshadri, S, Boerwinkle, E, Davies, NM, Giese, AK, Ikram, MK, Kittner, SJ, McKnight, B, Psaty, BM, Reiner, AP, Sargurupremraj, M, Taylor, KD, Fornage, M, Hamsten, A, Marz, W, Rosendaal, FR, Souto, JC, Dehghan, A, Johnson, AD, Morrison, AC, O'Donnell, CJ, Smith, NL, INVENT Consortium, MEGASTROKE Consortium Intl
Publikováno v:
BLOOD
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
de Vries, P S, Sabater-Lleal, M, Huffman, J E, Marten, J, Song, C, Pankratz, N, Bartz, T M, de Haan, H G, Delgado, G E, Eicher, J D, Martinez-Perez, A, Ward-Caviness, C K, Brody, J A, Chen, M-H, de Maat, M P M, Frånberg, M, Gill, D, Kleber, M E, Rivadeneira, F, Soria, J M, Tang, W, Tofler, G H, Uitterlinden, A G, van Hylckama Vlieg, A, Seshadri, S, Boerwinkle, E, Davies, N M, Giese, A-K, Ikram, M K, Kittner, S J, McKnight, B, Psaty, B M, Reiner, A P, Sargurupremraj, M, Taylor, K D, Fornage, M, Hamsten, A, März, W, Rosendaal, F R, Souto, J C, Dehghan, A, Johnson, A D, Morrison, A C, O'Donnell, C J & Smith, N L 2019, ' A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology ', Blood, vol. 133, no. 9, pp. 967-977 . https://doi.org/10.1182/blood-2018-05-849240
Blood, 133(9), 967-977. American Society of Hematology
Blood, 133(9), 967-977
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
de Vries, P S, Sabater-Lleal, M, Huffman, J E, Marten, J, Song, C, Pankratz, N, Bartz, T M, de Haan, H G, Delgado, G E, Eicher, J D, Martinez-Perez, A, Ward-Caviness, C K, Brody, J A, Chen, M-H, de Maat, M P M, Frånberg, M, Gill, D, Kleber, M E, Rivadeneira, F, Soria, J M, Tang, W, Tofler, G H, Uitterlinden, A G, van Hylckama Vlieg, A, Seshadri, S, Boerwinkle, E, Davies, N M, Giese, A-K, Ikram, M K, Kittner, S J, McKnight, B, Psaty, B M, Reiner, A P, Sargurupremraj, M, Taylor, K D, Fornage, M, Hamsten, A, März, W, Rosendaal, F R, Souto, J C, Dehghan, A, Johnson, A D, Morrison, A C, O'Donnell, C J & Smith, N L 2019, ' A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology ', Blood, vol. 133, no. 9, pp. 967-977 . https://doi.org/10.1182/blood-2018-05-849240
Blood, 133(9), 967-977. American Society of Hematology
Blood, 133(9), 967-977
Factor VII (FVII) is an important component of the coagulation cascade. Few genetic loci regulating FVII activity and/or levels have been discovered to date. We conducted a meta-analysis of nine genome-wide association studies of plasma FVII levels (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ee0c9817b2b3e415332a0a2d71f217
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2980
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2980
Autor:
Bandres‐Ciga, S, Noyce, AJ, Hemani, G, Nicolas, A, Calvo, A, Mora, G, Arosio, A, Barberis, M, Bartolomei, I, Battistini, S, Benigni, M, Borghero, G, Brunetti, M, Cammarosano, S, Cannas, A, Canosa, A, Capasso, M, Caponnetto, C, Caredda, C, Carrera, P, Casale, F, Cavallaro, S, Chiò, A, Colletti, T, Conforti, FL, Conte, A, Corrado, L, Costantino, E, D'Alfonso, S, Fasano, A, Femiano, C, Ferrarese, C, Fini, N, Floris, G, Fuda, G, Giannini, F, Grassano, M, Ilardi, A, La Bella, V, Lattante, S, Logroscino, G, Logullo, FO, Loi, D, Lunetta, C, Mancardi, G, Mandich, P, Mandrioli, J, Manera, U, Marangi, G, Marinou, K, Marrali, G, Marrosu, MG, Mazzini, L, Melis, M, Messina, S, Moglia, C, Monsurro, MR, Mosca, L, Occhineri, P, Origone, P, Pani, C, Penco, S, Petrucci, A, Piccirillo, G, Pirisi, A, Pisano, F, Pugliatti, M, Restagno, G, Ricci, C, Rita Murru, M, Riva, N, Sabatelli, M, Salvi, F, Santarelli, M, Sideri, R, Simone, I, Spataro, R, Tanel, R, Tedeschi, G, Tranquilli, S, Tremolizzo, L, Trojsi, F, Volanti, P, Zollino, M, Abramzon, Y, Arepalli, S, Baloh, RH, Bowser, R, Brady, CB, Brice, A, Broach, J, Campbell, RH, Camu, W, Chia, R, Cooper‐Knock, J, Cusi, D, Ding, J, Drepper, C, Drory, VE, Dunckley, TL, Eicher, JD, Faghri, F, Feldman, E, Kay Floeter, M, Fratta, P, Geiger, JT, Gerhard, G, Gibbs, JR, Gibson, SB, Glass, JD, Hardy, J, Harms, MB, Heiman‐Patterson, TD, Hernandez, DG, Jansson, L, Kamel, F, Kirby, J, Kowall, NW, Laaksovirta, H, Landi, F, Le Ber, I, Lumbroso, S, MacGowan, DJL, Maragakis, NJ, Mouzat, K, Murphy, NA, Myllykangas, L, Nalls, MA, Orrell, RW, Ostrow, LW, Pamphlett, R, Pickering‐Brown, S, Pioro, E, Pliner, HA, Pulst, SM, Ravits, JM, Renton, AE, Rivera, A, Robbrecht, W, Rogaeva, E, Rollinson, S, Rothstein, JD, Salvi, E, Scholz, SW, Sendtner, M, Shaw, PJ, Sidle, KC, Simmons, Z, Singleton, AB, Stone, DC, Sulkava, R, Tienari, PJ, Traynor, BJ, Trojanowski, JQ, Troncoso, JC, Van Damme, P, Van Deerlin, VM, Van Den Bosch, L, Zinman, L, Stone, DJ
Publikováno v:
Annals of neurology 85 (2019): 470–481. doi:10.1002/ana.25431
info:cnr-pdr/source/autori:Bandres-Ciga S; Noyce AJ; Hemani G; Nicolas A; Calvo A; Mora G; Arosio A; Barberis M; Bartolomei I; Battistini S; Benigni M; Borghero G; Brunetti M; Cammarosano S; Cannas A; Canosa A; Capasso M; Caponnetto C; Caredda C; Carrera P; Casale F; Cavallaro S; Chiò A; Colletti T; Conforti FL; Conte A; Corrado L; Costantino E; D'Alfonso S; Fasano A; Femiano C; Ferrarese C; Fini N; Floris G; Fuda G; Giannini F; Grassano M; Ilardi A; La Bella V; Lattante S; Logroscino G; Logullo FO; Loi D; Lunetta C; Mancardi G; Mandich P; Mandrioli J; Manera U; Marangi G; Marinou K; Marrali G; Marrosu MG; Mazzini L; Melis M; Messina S; Moglia C; Monsurro MR; Mosca L; Occhineri P; Origone P; Pani C; Penco S; Petrucci A; Piccirillo G; Pirisi A; Pisano F; Pugliatti M; Restagno G; Ricci C; Rita Murru M; Riva N; Sabatelli M; Salvi F; Santarelli M; Sideri R; Simone I; Spataro R; Tanel R; Tedeschi G; Tranquilli S; Tremolizzo L; Trojsi F; Volanti P; Zollino M; Abramzon Y; Arepalli S; Baloh RH; Bowser R; Brady CB; Brice A; Broach J; Campbell RH; Camu W; Chia R; Cooper-Knock J; Cusi D; Ding J; Drepper C; Drory VE; Dunckley TL; Eicher JD; Faghri F; Feldman E; Kay Floeter M; Fratta P; Geiger JT; Gerhard G; Gibbs JR; Gibson SB; Glass JD; Hardy J; Harms MB; Heiman-Patterson TD; Hernandez DG; Jansson L; Kamel F; Kirby J; Kowall NW; Laaksovirta H; Landi F; Le Ber I; Lumbroso S; MacGowan DJL; Maragakis NJ; Mouzat K; Murphy NA; Myllykangas L; Nalls MA; Orrell RW; Ostrow LW; Pamphlett R; Pickering-Brown S; Pioro E; Pliner HA; Pulst SM; Ravits JM; Renton AE; Rivera A; Robbrecht W; Rogaeva E; Rollinson S; Rothstein JD; Salvi E; Scholz SW; Sendtner M; Shaw PJ; Sidle KC; Simmons Z; Singleton AB; Stone DC; Sulkava R; Tienari PJ; Traynor BJ; Trojanowski JQ; Troncoso JC; Van Damme P; Van Deerlin VM; Van Den Bosch L; Zinman L; Stone DJ;/titolo:Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis/doi:10.1002%2Fana.25431/rivista:Annals of neurology/anno:2019/pagina_da:470/pagina_a:481/intervallo_pagine:470–481/volume:85
2019, ' Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis ', Annals of Neurology, vol. 85, no. 4, pp. 470-481 . https://doi.org/10.1002/ana.25431
Annals of Neurology
Annals of Neurology, Wiley, 2019, 85 (4), pp.470-481. ⟨10.1002/ana.25431⟩
info:cnr-pdr/source/autori:Bandres-Ciga S; Noyce AJ; Hemani G; Nicolas A; Calvo A; Mora G; Arosio A; Barberis M; Bartolomei I; Battistini S; Benigni M; Borghero G; Brunetti M; Cammarosano S; Cannas A; Canosa A; Capasso M; Caponnetto C; Caredda C; Carrera P; Casale F; Cavallaro S; Chiò A; Colletti T; Conforti FL; Conte A; Corrado L; Costantino E; D'Alfonso S; Fasano A; Femiano C; Ferrarese C; Fini N; Floris G; Fuda G; Giannini F; Grassano M; Ilardi A; La Bella V; Lattante S; Logroscino G; Logullo FO; Loi D; Lunetta C; Mancardi G; Mandich P; Mandrioli J; Manera U; Marangi G; Marinou K; Marrali G; Marrosu MG; Mazzini L; Melis M; Messina S; Moglia C; Monsurro MR; Mosca L; Occhineri P; Origone P; Pani C; Penco S; Petrucci A; Piccirillo G; Pirisi A; Pisano F; Pugliatti M; Restagno G; Ricci C; Rita Murru M; Riva N; Sabatelli M; Salvi F; Santarelli M; Sideri R; Simone I; Spataro R; Tanel R; Tedeschi G; Tranquilli S; Tremolizzo L; Trojsi F; Volanti P; Zollino M; Abramzon Y; Arepalli S; Baloh RH; Bowser R; Brady CB; Brice A; Broach J; Campbell RH; Camu W; Chia R; Cooper-Knock J; Cusi D; Ding J; Drepper C; Drory VE; Dunckley TL; Eicher JD; Faghri F; Feldman E; Kay Floeter M; Fratta P; Geiger JT; Gerhard G; Gibbs JR; Gibson SB; Glass JD; Hardy J; Harms MB; Heiman-Patterson TD; Hernandez DG; Jansson L; Kamel F; Kirby J; Kowall NW; Laaksovirta H; Landi F; Le Ber I; Lumbroso S; MacGowan DJL; Maragakis NJ; Mouzat K; Murphy NA; Myllykangas L; Nalls MA; Orrell RW; Ostrow LW; Pamphlett R; Pickering-Brown S; Pioro E; Pliner HA; Pulst SM; Ravits JM; Renton AE; Rivera A; Robbrecht W; Rogaeva E; Rollinson S; Rothstein JD; Salvi E; Scholz SW; Sendtner M; Shaw PJ; Sidle KC; Simmons Z; Singleton AB; Stone DC; Sulkava R; Tienari PJ; Traynor BJ; Trojanowski JQ; Troncoso JC; Van Damme P; Van Deerlin VM; Van Den Bosch L; Zinman L; Stone DJ;/titolo:Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis/doi:10.1002%2Fana.25431/rivista:Annals of neurology/anno:2019/pagina_da:470/pagina_a:481/intervallo_pagine:470–481/volume:85
2019, ' Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis ', Annals of Neurology, vol. 85, no. 4, pp. 470-481 . https://doi.org/10.1002/ana.25431
Annals of Neurology
Annals of Neurology, Wiley, 2019, 85 (4), pp.470-481. ⟨10.1002/ana.25431⟩
OBJECTIVE: To identify shared polygenic risk and causal associations in amyotrophic lateral sclerosis (ALS). METHODS: Linkage disequilibrium score regression and Mendelian randomization were applied in a large-scale, data-driven manner to explore gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ec44e96e87becc7f1c928039052519
http://hdl.handle.net/11591/406432
http://hdl.handle.net/11591/406432
Autor:
Howson, JMM, Zhao, W, Barnes, DR, Ho, W-K, Young, R, Paul, DS, Waite, LL, Freitag, DF, Fauman, EB, Salfati, EL, Sun, BB, Eicher, JD, Johnson, AD, Sheu, WHH, Nielsen, SF, Lin, W-Y, Surendran, P, Malarstig, A, Wilk, JB, Tybjærg-Hansen, A, Rasmussen, KL, Kamstrup, PR, Deloukas, P, Erdmann, J, Kathiresan, S, Samani, NJ, Schunkert, H, Watkins, H, CARDIoGRAMplusC4D, Do, R, Rader, DJ, Johnson, JA, Hazen, SL, Quyyumi, AA, Spertus, JA, Pepine, CJ, Franceschini, N, Justice, A, Reiner, AP, Buyske, S, Hindorff, LA, Carty, CL, North, KE, Kooperberg, C, Boerwinkle, E, Young, K, Graff, M, Peters, U, Absher, D, Hsiung, CA, Lee, W-J, Taylor, KD, Chen, Y-H, Lee, I-T, Guo, X, Chung, R-H, Hung, Y-J, Rotter, JI, Juang, J-MJ, Quertermous, T, Wang, T-D, Rasheed, A, Frossard, P, Alam, DS, Majumder, AAS, Di Angelantonio, E, Chowdhury, R, EPIC-CVD, Chen, Y-DI, Nordestgaard, BG, Assimes, TL, Danesh, J, Butterworth, AS, Saleheen, D
Publikováno v:
Nature genetics, vol 49, iss 7
Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Although 58 genomic regions have been associated with CAD thus far, most of the heritability is unexplained, indicating that additional susceptibility loci await i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd3afacb7ebf56333f3f883b8c384da
https://escholarship.org/uc/item/26s3k8qt
https://escholarship.org/uc/item/26s3k8qt
Autor:
Song, C, Burgess, S, Eicher, JD, O'Donnell, CJ, Johnson, AD, Huang, J, Sabater-Lleal, M, Asselbergs, FW, Tregouet, D, Shin, SY, Ding, J, Baumert, J, Oudot-Mellakh, T, Folkersen, L, Smith, NL, Williams, SM, Ikram, MA, Kleber, ME, Becker, DM, Truong, V, Mychaleckyj, JC, Tang, W, Yang, Q, Sennblad, B, Moore, JH, Williams, FMK, Dehghan, A, Silbernagel, G, Schrijvers, EMC, Smith, S, Karakas, M, Tofler, GH, Silveira, A, Navis, GJ, Lohman, K, Chen, MH, Peters, A, Goel, A, Hopewell, JC, Chambers, JC, Saleheen, D, Lundmark, P, Psaty, BM, Strawbridge, RJ, Boehm, BO, Carter, AM, Meisinger, C, Peden, JF, Bis, JC, McKnight, B, Öhrvik, J, Taylor, K, Franzosi, MG, Seedorf, U, Collins, R, Franco-Cereceda, A, Syvänen, AC, Goodall, AH, Yanek, LR, Cushman, M, Müller-Nurasyid, M, Folsom, AR, Basu, S, Matijevic, N, Van Gilst, WH, Kooner, JS, Danesh, J, Clarke, R, Meigs, JB, Kathiresan, S, Reilly, MP, Klopp, N, Harris, TB, Winkelmann, BR, Grant, PJ, Hillege, HL, Watkins, H, Spector, TD, Becker, LC, Tracy, RP, März, W, Uitterlinden, AG, Eriksson, P, Cambien, F, Morange, PE, Koenig, W, Soranzo, N, Van der Harst, P, Liu, Y, Hamsten, A, Ehret, GB, Munroe, PB, Rice, KM, Bochud, M, Chasman, DI, Smith, AV
Publikováno v:
Journal of the American Heart Association, 6(6):e004918. Wiley-Blackwell Publishing Ltd
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association, vol 6, iss 6
Journal of the American Heart Association, 6(6). Wiley-Blackwell
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association, vol 6, iss 6
Journal of the American Heart Association, 6(6). Wiley-Blackwell
Background Plasminogen activator inhibitor type 1 ( PAI ‐1) plays an essential role in the fibrinolysis system and thrombosis. Population studies have reported that blood PAI ‐1 levels are associated with increased risk of coronary heart disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabb33728a45e61e96cf5736dad02211
https://pure.eur.nl/en/publications/a644d69d-078f-4e47-abaa-b2c097ffb31e
https://pure.eur.nl/en/publications/a644d69d-078f-4e47-abaa-b2c097ffb31e
Autor:
Day, FR, Ruth, KS, Thompson, DJ, Lunetta, KL, Pervjakova, N, Chasman, DI, Stolk, Lisette, Finucane, HK, Sulem, P, Bulik-Sullivan, B, Esko, T, Johnson, AD, Elks, CE, Franceschini, N, He, C, Altmaier, E, Brody, JA, Franke, LL, Huffman, JE, Keller, MF, McArdle, PF, Nutile, T, Porcu, E, Robino, A, Rose, LM, Schick, UM, Smith, JA, Teumer, A, Traglia, M, Vuckovic, D, Yao, J, Zhao, W, Albrecht, E, Amin, Najaf, Corre, T, Hottenga, JJ (Jouke Jan), Mangino, M, Smith, AV, Tanaka, T, Abecasis, GR, Andrulis, IL, Anton-Culver, H, Antoniou, AC, Arndt, V, Arnold, AM, Barbieri, C, Beckmann, MW, Beeghly-Fadiel, A, Benitez, J, Bernstein, L, Bielinski, SJ, Blomqvist, C, Boerwinkle, E, Bogdanova, NV, Bojesen, SE, Bolla, MK, Borresen-Dale, AL, Boutin, TS, Brauch, H, Brenner, H, Bruning, T, Burwinkel, B, Campbell, A (Archie), Campbell, H, Chanock, SJ, Chapman, JR, Chen, YDI, Chenevix-Trench, G, Couch, FJ, Coviello, AD, Cox, A, Czene, K, Darabi, H, de Vivo, I, Demerath, EW, Dennis, J, Devilee, P, Dork, T, dos-Santos-Silva, I, Dunning, AM, Eicher, JD, Fasching, PA, Faul, JD, Figueroa, J, Flesch-Janys, D, Gandin, I, Garcia, ME, Garcia-Closas, M, Giles, GG, Girotto, GG, Goldberg, MS, Gonzalez-Neira, A, Goodarzi, MO, Grove, ML, Gudbjartsson, DF, Guenel, P, Guo, XQ, Haiman, CA, Hall, P, Hamann, U, Henderson, BE, Hocking, LJ, Hofman, Bert, Homuth, G, Hooning, Maartje, Hopper, JL, Hu, FB, Huang, JY, Humphreys, K, Hunter, DJ, Jakubowska, A, Jones, SE, Kabisch, M, Karasik, D, Knight, JA, Kolcic, I, Kooperberg, C, Kosma, VM, Kriebel, J, Kristensen, V, Lambrechts, D, Langenberg, C, Li, JM, Li, X, Lindstrom, S, Liu, YM, Luan, JA, Lubinski, J, Magi, R, Mannermaa, A, Manz, J, Margolin, S, Marten, J, Martin, NG, Masciullo, C, Meindl, A, Michailidou, K, Mihailov, E, Milani, L, Milne, RL, Muller-Nurasyid, M, Nalls, M, Neale, BM, Nevanlinna, H, Neven, P, Newman, AB, Nordestgaard, BG, Olson, JE, Padmanabhan, S, Peterlongo, P, Peters, U, Petersmann, A, Peto, J, Pharoah, PDP, Pirastu, NN, Pirie, A, Pistis, G, Polasek, O, Porteous, D, Psaty, BM, Pylkas, K, Radice, P, Raffel, LJ, Rivadeneira, Fernando, Rudan, I, Rudolph, A, Ruggiero, D, Sala, CF, Sanna, S, Sawyer, EJ, Schlessinger, D, Schmidt, MK (Marjanka), Schmidt, F, Schmutzler, RK, Schoemaker, MJ, Scott, RA, Seynaeve, Caroline, Simard, J, Sorice, R, Southey, MC, Stockl, D, Strauch, K, Swerdlow, A, Taylor, KD, Thorsteinsdottir, U, Toland, AE, Tomlinson, I, Truong, T, Tryggvadottir, L, Turner, ST, Vozzi, D, Wang, Q (Qing), Wellons, M, Willemsen, G, Wilson, JF, Winqvist, R, Wolffenbuttel, BBHR, Wright, AF, Yannoukakos, D, Zemunik, T, Zheng, W, Zygmunt, M, Bergmann, S, Boomsma, DI, Buring, JE, Ferrucci, L, Montgomery, GW, Gudnason, V, Spector, TD, Duijn, Cornelia, Alizadeh, BZ, Ciullo, M, Crisponi, L, Easton, DF, Gasparini, PP, Gieger, C, Harris, TB, Hayward, C, Kardia, SLR, Kraft, P, McKnight, B, Metspalu, A, Morrison, AC, Reiner, AP, Ridker, PM, Rotter, JI, Toniolo, D, Uitterlinden, André, Ulivi, S, Volzke, H, Wareham, NJ, Weir, DR, Yerges-Armstrong, LM, Price, AL, Stefansson, K, Visser, Jenny, Ong, KK, Chang-Claude, J, Murabito, JM, Perry, JRB, Murray, A
Publikováno v:
Obstetrical and Gynecological Survey, 70(12), 758-762. Lippincott Williams and Wilkins
Day, F R, Ruth, K S, Thompson, D J, Lunetta, K L, Pervjakova, N, Chasman, D I, Stolk, L, Finucane, H K, Sulem, P, Bulik-Sullivan, B, Esko, T, Johnson, A D, Elks, C E, Franceschini, N, He, C, Altmaier, E, Brody, J A, Franke, L L, Huffman, J E, Keller, M F, McArdle, P F, Nutile, T, Porcu, E, Robino, A, Rose, L M, Schick, U M, Smith, J A, Teumer, A, Traglia, M, Vuckovic, D, Yao, J, Zhao, W, Albrecht, E, Amin, N, Corre, T, Hottenga, J, Mangino, M, Smith, A V, Tanaka, T, Abecasis, G R, Andrulis, I L, Anton-Culver, H, Antoniou, A C, Arndt, V, Arnold, A M, Barbieri, C, Beckmann, M W, Beeghly-Fadiel, A, Benitez, J, Bernstein, L, Bielinski, S J, Blomqvist, C, Boerwinkle, E, Bogdanova, N V, Bojesen, S E, Bolla, M K, Borresen-Dale, A, Boutin, T S, Brauch, H, Brenner, H, Bruening, T, Burwinkel, B, Campbell, A, Campbell, H, Chanock, S J, Chapman, J R, Chen, Y I, Chenevix-Trench, G, Couch, F J, Coviello, A D, Cox, A, Czene, K, Darabi, H, De Vivo, I, Demerath, E W, Dennis, J, Devilee, P, Doerk, T, dos-Santos-Silva, I, Dunning, A M, Eicher, J D, Fasching, P A, Faul, J D, Figueroa, J, Flesch-Janys, D, Gandin, I, Garcia, M E, Garcia-Closas, M, Giles, G G, Girotto, G G, Goldberg, M S, Gonzalez-Neira, A, Goodarzi, M O, Grove, M L, Gudbjartsson, D F, Guenel, P, Guo, X, Haiman, C A, Hall, P, Hamann, U, Henderson, B E, Hocking, L J, Hofman, A, Homuth, G, Hooning, M J, Hopper, J L, Hu, F B, Huang, J, Humphreys, K, Hunter, D J, Jakubowska, A, Jones, S E, Kabisch, M, Karasik, D, Knight, J A, Kolcic, I, Kooperberg, C, Kosma, V, Kriebel, J, Kristensen, V, Lambrechts, D, Langenberg, C, Li, J, Li, X, Lindstroem, S, Liu, Y, Luan, J, Lubinski, J, Maegi, R, Mannermaa, A, Manz, J, Margolin, S, Marten, J, Martin, N G, Masciullo, C, Meindl, A, Michailidou, K, Mihailov, E, Milani, L, Milne, R L, Mueller-Nurasyid, M, Nalls, M, Neale, B M, Nevanlinna, H, Neven, P, Newman, A B, Nordestgaard, B G, Olson, J E, Padmanabhan, S, Peterlongo, P, Peters, U, Petersmann, A, Peto, J, Pharoah, P D P, Pirastu, N N, Pirie, A, Pistis, G, Polasek, O, Porteous, D, Psaty, B M, Pylkaes, K, Radice, P, Raffel, L J, Rivadeneira, F, Rudan, I, Rudolph, A, Ruggiero, D, Sala, C F, Sanna, S, Sawyer, E J, Schlessinger, D, Schmidt, M K, Schmidt, F, Schmutzler, R K, Schoemaker, M J, Scott, R A, Seynaeve, C M, Simard, J, Sorice, R, Southey, M C, Stoeckl, D, Strauch, K, Swerdlow, A, Taylor, K D, Thorsteinsdottir, U, Toland, A E, Tomlinson, I, Truong, T, Tryggvadottir, L, Turner, S T, Vozzi, D, Wang, Q, Wellons, M, Willemsen, G, Wilson, J F, Winqvist, R, Wolffenbuttel, B B H R, Wright, A F, Yannoukakos, D, Zemunik, T, Zheng, W, Zygmunt, M, Bergmann, S, Boomsma, D I, Buring, J E, Ferrucci, L, Montgomery, G W, Gudnason, V, Spector, T D, van Duijn, C M, Alizadeh, BZ, Ciullo, M, Crisponi, L, Easton, D F, Gasparini, P P, Gieger, C, Harris, T B, Hayward, C, Kardia, S L R, Kraft, P, McKnight, B, Metspalu, A, Morrison, A C, Reiner, A P, Ridker, P M, Rotter, J I, Toniolo, D, Uitterlinden, A G, Ulivi, S, Voelzke, H, Wareham, N J, Weir, D R, Yerges-Armstrong, L M, Price, A L, Stefansson, K, Visser, J A, Ong, K K, Chang-Claude, J, Murabito, J M, Perry, J R B & Murray, A 2015, ' Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair EDITORIAL COMMENT ', Obstetrical and Gynecological Survey, vol. 70, no. 12, pp. 758-762 . https://doi.org/10.1097/01.ogx.0000473766.71624.99
Obstetrical and Gynecological Survey, 70(12), 758-762. Lippincott Williams & Wilkins
Day, F R, Ruth, K S, Thompson, D J, Lunetta, K L, Pervjakova, N, Chasman, D I, Stolk, L, Finucane, H K, Sulem, P, Bulik-Sullivan, B, Esko, T, Johnson, A D, Elks, C E, Franceschini, N, He, C, Altmaier, E, Brody, J A, Franke, L L, Huffman, J E, Keller, M F, McArdle, P F, Nutile, T, Porcu, E, Robino, A, Rose, L M, Schick, U M, Smith, J A, Teumer, A, Traglia, M, Vuckovic, D, Yao, J, Zhao, W, Albrecht, E, Amin, N, Corre, T, Hottenga, J, Mangino, M, Smith, A V, Tanaka, T, Abecasis, G R, Andrulis, I L, Anton-Culver, H, Antoniou, A C, Arndt, V, Arnold, A M, Barbieri, C, Beckmann, M W, Beeghly-Fadiel, A, Benitez, J, Bernstein, L, Bielinski, S J, Blomqvist, C, Boerwinkle, E, Bogdanova, N V, Bojesen, S E, Bolla, M K, Borresen-Dale, A, Boutin, T S, Brauch, H, Brenner, H, Bruening, T, Burwinkel, B, Campbell, A, Campbell, H, Chanock, S J, Chapman, J R, Chen, Y I, Chenevix-Trench, G, Couch, F J, Coviello, A D, Cox, A, Czene, K, Darabi, H, De Vivo, I, Demerath, E W, Dennis, J, Devilee, P, Doerk, T, dos-Santos-Silva, I, Dunning, A M, Eicher, J D, Fasching, P A, Faul, J D, Figueroa, J, Flesch-Janys, D, Gandin, I, Garcia, M E, Garcia-Closas, M, Giles, G G, Girotto, G G, Goldberg, M S, Gonzalez-Neira, A, Goodarzi, M O, Grove, M L, Gudbjartsson, D F, Guenel, P, Guo, X, Haiman, C A, Hall, P, Hamann, U, Henderson, B E, Hocking, L J, Hofman, A, Homuth, G, Hooning, M J, Hopper, J L, Hu, F B, Huang, J, Humphreys, K, Hunter, D J, Jakubowska, A, Jones, S E, Kabisch, M, Karasik, D, Knight, J A, Kolcic, I, Kooperberg, C, Kosma, V, Kriebel, J, Kristensen, V, Lambrechts, D, Langenberg, C, Li, J, Li, X, Lindstroem, S, Liu, Y, Luan, J, Lubinski, J, Maegi, R, Mannermaa, A, Manz, J, Margolin, S, Marten, J, Martin, N G, Masciullo, C, Meindl, A, Michailidou, K, Mihailov, E, Milani, L, Milne, R L, Mueller-Nurasyid, M, Nalls, M, Neale, B M, Nevanlinna, H, Neven, P, Newman, A B, Nordestgaard, B G, Olson, J E, Padmanabhan, S, Peterlongo, P, Peters, U, Petersmann, A, Peto, J, Pharoah, P D P, Pirastu, N N, Pirie, A, Pistis, G, Polasek, O, Porteous, D, Psaty, B M, Pylkaes, K, Radice, P, Raffel, L J, Rivadeneira, F, Rudan, I, Rudolph, A, Ruggiero, D, Sala, C F, Sanna, S, Sawyer, E J, Schlessinger, D, Schmidt, M K, Schmidt, F, Schmutzler, R K, Schoemaker, M J, Scott, R A, Seynaeve, C M, Simard, J, Sorice, R, Southey, M C, Stoeckl, D, Strauch, K, Swerdlow, A, Taylor, K D, Thorsteinsdottir, U, Toland, A E, Tomlinson, I, Truong, T, Tryggvadottir, L, Turner, S T, Vozzi, D, Wang, Q, Wellons, M, Willemsen, G, Wilson, J F, Winqvist, R, Wolffenbuttel, B B H R, Wright, A F, Yannoukakos, D, Zemunik, T, Zheng, W, Zygmunt, M, Bergmann, S, Boomsma, D I, Buring, J E, Ferrucci, L, Montgomery, G W, Gudnason, V, Spector, T D, van Duijn, C M, Alizadeh, BZ, Ciullo, M, Crisponi, L, Easton, D F, Gasparini, P P, Gieger, C, Harris, T B, Hayward, C, Kardia, S L R, Kraft, P, McKnight, B, Metspalu, A, Morrison, A C, Reiner, A P, Ridker, P M, Rotter, J I, Toniolo, D, Uitterlinden, A G, Ulivi, S, Voelzke, H, Wareham, N J, Weir, D R, Yerges-Armstrong, L M, Price, A L, Stefansson, K, Visser, J A, Ong, K K, Chang-Claude, J, Murabito, J M, Perry, J R B & Murray, A 2015, ' Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair EDITORIAL COMMENT ', Obstetrical and Gynecological Survey, vol. 70, no. 12, pp. 758-762 . https://doi.org/10.1097/01.ogx.0000473766.71624.99
Obstetrical and Gynecological Survey, 70(12), 758-762. Lippincott Williams & Wilkins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aee02ec386b900e68322f081c3e42e1a
https://research.vu.nl/en/publications/2398f5ac-481a-458c-bb9b-29df62fa401b
https://research.vu.nl/en/publications/2398f5ac-481a-458c-bb9b-29df62fa401b
Autor:
Eicher, JD, Powers, NR, Miller, LL, Akshoomoff, N, Amaral, DG, Bloss, CS, Libiger, O, Schork, NJ, Darst, BF, Casey, BJ, Chang, L, Ernst, T, Frazier, J, Kaufmann, WE, Keating, B, Kenet, T, Kennedy, D, Mostofsky, S, Murray, SS, Sowell, ER, Bartsch, H, Kuperman, JM, Brown, TT, Hagler, DJ, Dale, AM, Jernigan, TL, St Pourcain, B, Davey Smith, G, Ring, SM, Gruen, JR, Pediatric Imaging, Neurocognition, and Genetics Study
Publikováno v:
Genes, brain, and behavior, vol 12, iss 8
Written and verbal languages are neurobehavioral traits vital to the development of communication skills. Unfortunately, disorders involving these traits-specifically reading disability (RD) and language impairment (LI)-are common and prevent affecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::405d97eeaaf0f94a3bd23cc568016887
https://escholarship.org/uc/item/6d54k70c
https://escholarship.org/uc/item/6d54k70c
Autor:
Justice, AE, Winkler, TW, Feitosa, MF, Graff, M, Fisher, VA, Young, K, Barata, L, Deng, X, Czajkowski, J, Hadley, D, Ngwa, JS, Ahluwalia, TS, Chu, AY, Heard-Costa, NL, Lim, E, Perez, J, Eicher, JD, Kutalik, Z, Xue, L, Mahajan, A, Renström, F, Wu, J, Qi, Q, Ahmad, S, Alfred, T, Amin, N, Bielak, LF, Bonnefond, A, Bragg, J, Cadby, G, Chittani, M, Coggeshall, S, Corre, T, Direk, N, Eriksson, J, Fischer, K, Gorski, M, Neergaard Harder, M, Horikoshi, M, Huang, T, Huffman, JE, Jackson, AU, Justesen, JM, Kanoni, S, Kinnunen, L, Kleber, ME, Komulainen, P, Kumari, M, Lim, U, Luan, J, Lyytikäinen, L-P, Mangino, M, Manichaikul, A, Marten, J, Middelberg, RPS, Müller-Nurasyid, M, Navarro, P, Pérusse, L, Pervjakova, N, Sarti, C, Smith, AV, Smith, JA, Stančáková, A, Strawbridge, RJ, Stringham, HM, Sung, YJ, Tanaka, T, Teumer, A, Trompet, S, Van Der Laan, SW, Van Der Most, PJ, Van Vliet-Ostaptchouk, JV, Vedantam, SL, Verweij, N, Vink, JM, Vitart, V, Wu, Y, Yengo, L, Zhang, W, Hua Zhao, J, Zimmermann, ME, Zubair, N, Abecasis, GR, Adair, LS, Afaq, S, Afzal, U, Bakker, SJL, Bartz, TM, Beilby, J, Bergman, RN, Bergmann, S, Biffar, R, Blangero, J, Boerwinkle, E, Bonnycastle, LL, Bottinger, E, Braga, D, Buckley, BM, Buyske, S, Campbell, H, Chambers, JC, Collins, FS, Curran, JE, De Borst, GJ, De Craen, AJM, De Geus, EJC, Dedoussis, G, Delgado, GE, Den Ruijter, HM, Eiriksdottir, G, Eriksson, AL, Esko, T, Faul, JD, Ford, I, Forrester, T, Gertow, K, Gigante, B, Glorioso, N, Gong, J, Grallert, H, Grammer, TB, Grarup, N, Haitjema, S, Hallmans, G, Hamsten, A, Hansen, T, Harris, TB, Hartman, CA, Hassinen, M, Hastie, ND, Heath, AC, Hernandez, D, Hindorff, L, Hocking, LJ, Hollensted, M, Holmen, OL, Homuth, G, Jan Hottenga, J, Huang, J, Hung, J, Hutri-Kähönen, N, Ingelsson, E, James, AL, Jansson, J-O, Jarvelin, M-R, Jhun, MA, Jørgensen, ME, Juonala, M, Kähönen, M, Karlsson, M, Koistinen, HA, Kolcic, I, Kolovou, G, Kooperberg, C, Krämer, BK, Kuusisto, J, Kvaløy, K, Lakka, TA, Langenberg, C, Launer, LJ, Leander, K, Lee, NR, Lind, L, Lindgren, CM, Linneberg, A, Lobbens, S, Loh, M, Lorentzon, M, Luben, R, Lubke, G, Ludolph-Donislawski, A, Lupoli, S, Madden, PAF, Männikkö, R, Marques-Vidal, P, Martin, NG, McKenzie, CA, McKnight, B, Mellström, D, Menni, C, Montgomery, GW, Musk, AB, Narisu, N, Nauck, M, Nolte, IM, Oldehinkel, AJ, Olden, M, Ong, KK, Padmanabhan, S, Peyser, PA, Pisinger, C, Porteous, DJ, Raitakari, OT, Rankinen, T, Rao, DC, Rasmussen-Torvik, LJ, Rawal, R, Rice, T, Ridker, PM, Rose, LM, Bien, SA, Rudan, I, Sanna, S, Sarzynski, MA, Sattar, N, Savonen, K, Schlessinger, D, Scholtens, S, Schurmann, C, Scott, RA, Sennblad, B, Siemelink, MA, Silbernagel, G, Slagboom, PE, Snieder, H, Staessen, JA, Stott, DJ, Swertz, MA, Swift, AJ, Taylor, KD, Tayo, BO, Thorand, B, Thuillier, D, Tuomilehto, J, Uitterlinden, AG, Vandenput, L, Vohl, M-C, Völzke, H, Vonk, JM, Waeber, G, Waldenberger, M, Westendorp, RGJ, Wild, S, Willemsen, G, Wolffenbuttel, BHR, Wong, A, Wright, AF, Zhao, W, Zillikens, MC, Baldassarre, D, Balkau, B, Bandinelli, S, Böger, CA, Boomsma, DI, Bouchard, C, Bruinenberg, M, Chasman, DI, Chen, Y-D, Chines, PS, Cooper, RS, Cucca, F, Cusi, D, Faire, UD, Ferrucci, L, Franks, PW, Froguel, P, Gordon-Larsen, P, Grabe, H-J, Gudnason, V, Haiman, CA, Hayward, C, Hveem, K, Johnson, AD, Wouter Jukema, J, Kardia, SLR, Kivimaki, M, Kooner, JS, Kuh, D, Laakso, M, Lehtimäki, T, Marchand, LL, März, W, McCarthy, MI, Metspalu, A, Morris, AP, Ohlsson, C, Palmer, LJ, Pasterkamp, G, Pedersen, O, Peters, A, Peters, U, Polasek, O, Psaty, BM, Qi, L, Rauramaa, R, Smith, BH, Sørensen, TIA, Strauch, K, Tiemeier, H, Tremoli, E, Van Der Harst, P, Vestergaard, H, Vollenweider, P, Wareham, NJ, Weir, DR, Whitfield, JB, Wilson, JF, Tyrrell, J, Frayling, TM, Barroso, I, Boehnke, M, Deloukas, P, Fox, CS, Hirschhorn, JN, Hunter, DJ, Spector, TD, Strachan, DP, Van Duijn, CM, Heid, IM, Mohlke, KL, Marchini, J, Loos, RJF, Kilpeläinen, TO, Liu, C-T, Borecki, IB, North, KE, Cupples, LA
Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data from 51,080 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c05fbe865ce0f0bee645db9b9f22308
Autor:
Johnson JO; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland., Chia R; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland., Miller DE; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle.; Department of Pediatrics, Division of Genetic Medicine, Seattle Children's Hospital, University of Washington, Seattle., Li R; Department of Pediatrics, Children's Hospital of Richmond at VCU, Richmond, Virginia., Kumaran R; Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland., Abramzon Y; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom., Alahmady N; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.; Department of Biology, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia., Renton AE; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Topp SD; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.; UK Dementia Research Institute at King's College London, London, United Kingdom., Gibbs JR; Computational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland., Cookson MR; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom., Sabir MS; Neurodegenerative Diseases Research Unit, Laboratory of Neurogenetics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland., Dalgard CL; Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland., Troakes C; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Jones AR; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Shatunov A; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Iacoangeli A; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Al Khleifat A; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Ticozzi N; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Silani V; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Gellera C; Unit of Genetics of Neurodegenerative and Metabolic Diseases, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy., Blair IP; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia., Dobson-Stone C; The University of Sydney, Brain and Mind Centre and School of Medical Sciences, Faculty of Medicine and Health, Camperdown, Australia.; School of Medical Sciences, University of New South Wales, Kensington, Australia., Kwok JB; The University of Sydney, Brain and Mind Centre and School of Medical Sciences, Faculty of Medicine and Health, Camperdown, Australia.; School of Medical Sciences, University of New South Wales, Kensington, Australia., Bonkowski ES; Department of Pediatrics, Division of Genetic Medicine, Seattle Children's Hospital, University of Washington, Seattle., Palvadeau R; Suna and Inan Kırac Foundation, Neurodegeneration Research Laboratory, KUTTAM, School of Medicine, Koc University, Istanbul, Turkey., Tienari PJ; Department of Neurology, Helsinki University Hospital and Translational Immunology Programme, Biomedicum, University of Helsinki, Helsinki, Finland., Morrison KE; Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, United Kingdom., Shaw PJ; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom., Al-Chalabi A; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.; Department of Neurology, King's College Hospital, London, United Kingdom., Brown RH Jr; Department of Neurology, University of Massachusetts Medical School, Worcester., Calvo A; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Mora G; ALS Center, ICS Maugeri, IRCCS, Milan, Italy., Al-Saif H; Department of Neurology, Children's Hospital of Richmond at VCU, Richmond, Virginia., Gotkine M; Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Leigh F; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle., Chang IJ; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle., Perlman SJ; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle., Glass I; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle.; Department of Pediatrics, Division of Genetic Medicine, Seattle Children's Hospital, University of Washington, Seattle., Scott AI; Department of Laboratories, Seattle Children's Hospital, Seattle, Washington.; Department of Laboratory Medicine, University of Washington, Seattle., Shaw CE; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.; UK Dementia Research Institute at King's College London, London, United Kingdom., Basak AN; Suna and Inan Kırac Foundation, Neurodegeneration Research Laboratory, KUTTAM, School of Medicine, Koc University, Istanbul, Turkey., Landers JE; Department of Neurology, University of Massachusetts Medical School, Worcester., Chiò A; ALS Center, 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Neurology 1, AOU Città della Salute e della Scienza, Turin, Italy., Crawford TO; Department of Neurology, Johns Hopkins University, Baltimore, Maryland.; Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland., Smith BN; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Traynor BJ; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.; Department of Neurology, Johns Hopkins University, Baltimore, Maryland.; National Institute of Neurological Disorders and Stroke, Bethesda, Maryland., Smith BN; Centre for Neurodegeneration Research, King's College London, Department of Clinical Neuroscience, Institute of Psychiatry, London, United Kingdom., Ticozzi N; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Fallini C; Department of Neurology, University of Massachusetts Medical School, Worcester., Gkazi AS; Centre for Neurodegeneration Research, King's College London, Department of Clinical Neuroscience, Institute of Psychiatry, London, United Kingdom., Topp SD; Centre for Neurodegeneration Research, King's College London, Department of Clinical Neuroscience, Institute of Psychiatry, London, United Kingdom.; UK Dementia Research Institute at King's College London, London, United Kingdom., Scotter EL; Centre for Brain Research, University of Auckland, Auckland, New Zealand., Kenna KP; Department of Neurology, University of Massachusetts Medical School, Worcester., Keagle P; Department of Neurology, University of Massachusetts Medical School, Worcester., Tiloca C; Department of Neurology, IRCCS Istituto Auxologico Italiano, Milan, Italy., Vance C; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, King's College London, London, United Kingdom., Troakes C; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, King's College London, London, United Kingdom., Colombrita C; Department of Neurology, IRCCS Istituto Auxologico Italiano, Milan, Italy., King A; Centre for Neurodegeneration Research, King's College London, Department of Clinical Neuroscience, Institute of Psychiatry, London, United Kingdom., Pensato V; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy., Castellotti B; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy., Baas F; Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Ten Asbroek ALMA; Department of Neurogenetics and Neurology, Academic Medical Centre, Amsterdam, the Netherlands., McKenna-Yasek D; Department of Neurology, University of Massachusetts Medical School, Worcester., McLaughlin RL; Population Genetics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Republic of Ireland., Polak M; Department of Neurology, Emory University, Atlanta, Georgia., Asress S; Department of Neurology, Emory University, Atlanta, Georgia., Esteban-Pérez J; Unidad de ELA, Instituto de Investigación Hospital 12 de Octubre de Madrid, SERMAS, and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER U-723), Madrid, Spain., Stevic Z; Neurology Clinic, Clinical Center of Serbia School of Medicine, University of Belgrade, Belgrade, Serbia., D'Alfonso S; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy., Mazzini L; ALS Center, Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, Italy., Comi GP; Neurology Unit, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Del Bo R; Neurology Unit, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Ceroni M; Department of Brain and Behavior, University of Pavia, Pavia, Italy.; General Neurology Unit, IRCCS Mondino Foundation, Pavia, Italy., Gagliardi S; Genomic and Post-Genomic Center, Mondino Foundation-IRCCS, Pavia, Italy., Querin G; Department of Neurosciences, University of Padova, Padova, Italy., Bertolin C; Department of Neurosciences, University of Padova, Padova, Italy., van Rheenen W; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Rademakers R; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida., van Blitterswijk M; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida., Lauria G; 3rd Neurology Unit, Motor Neuron Diseases Center, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy., Duga S; Humanitas Clinical and Research Center-IRCCS, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Corti S; Neurology Unit, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Cereda C; Genomic and Post-Genomic Center, Mondino Foundation-IRCCS, Pavia, Italy., Corrado L; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy., Sorarù G; Department of Neurosciences, University of Padova, Padova, Italy., Williams KL; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia., Nicholson GA; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.; Molecular Medicine Laboratory, Clinical Sciences Building, Concord Hospital, Concord, Australia., Blair IP; Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia., Leblond-Manry C; Human Genetics and Cognitive Functions Unit, Institut Pasteur, Paris, France., Rouleau GA; Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada., Hardiman O; Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Republic of Ireland., Morrison KE; Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, United Kingdom., Veldink JH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., van den Berg LH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Al-Chalabi A; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, King's College London, London, United Kingdom., Pall H; School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom., Shaw PJ; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom., Turner MR; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Talbot K; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Taroni F; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy., García-Redondo A; Unidad de ELA, Instituto de Investigación Hospital 12 de Octubre de Madrid, SERMAS, and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER U-723), Madrid, Spain., Wu Z; Department of Bioinformatics and Computational Biology, Worcester Polytechnic Institute, Worcester, Massachusetts., Glass JD; Department of Neurology, Emory University, Atlanta, Georgia., Gellera C; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy., Ratti A; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Brown RH Jr; Department of Neurology, University of Massachusetts Medical School, Worcester., Silani V; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Shaw CE; UK Dementia Research Institute at King's College London, London, United Kingdom.; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, King's College London, London, United Kingdom., Landers JE; Department of Neurology, University of Massachusetts Medical School, Worcester., Dalgard CL; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland., Adeleye A; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Soltis AR; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Alba C; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Viollet C; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Bacikova D; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Hupalo DN; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Sukumar G; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Pollard HB; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland., Wilkerson MD; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Martinez EM; The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland., Abramzon Y; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland.; Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, United Kingdom., Ahmed S; Neurodegenerative Diseases Research Unit, Laboratory of Neurogenetics, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland., Arepalli S; Genomics Technology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Baloh RH; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California., Bowser R; Division of Neurology, Barrow Neurological Institute, Phoenix, Arizona., Brady CB; Research and Development Service, Veterans Affairs Boston Healthcare System, Boston, Massachusetts., Brice A; Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière, Université Pierre et Marie Curie, Paris, France.; INSERM U975, Paris, France., Broach J; Department of Biochemistry, Penn State College of Medicine, Hershey, Pennsylvania., Campbell RH; Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana., Camu W; ALS Reference Center, Gui de Chauliac Hospital, CHU and University of Montpellier, Montpellier, France., Chia R; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Cooper-Knock J; Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom., Ding J; Computational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Drepper C; Institute for Clinical Neurobiology, University of Würzburg, Würzburg, Germany., Drory VE; Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel., Dunckley TL; Neurodegenerative Disease Research Center, Biodesign Institute, Arizona State University, Tempe., Eicher JD; Department of Genetics and Pharmacogenomics, Merck Research Laboratories, Merck, West Point, Pennsylvania., England BK; Human Genetics Branch, National Institute of Mental Health, Bethesda, Maryland., Faghri F; Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana.; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Feldman E; Department of Neurology, University of Michigan, Ann Arbor., Floeter MK; Motor Neuron Disorders Unit, Laboratory of Neurogenetics, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland., Fratta P; Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, United Kingdom., Geiger JT; Neurodegenerative Diseases Research Unit, Laboratory of Neurogenetics, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland., Gerhard G; Department of Pathology, Penn State College of Medicine, Hershey, Pennsylvania., Gibbs JR; Computational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Gibson SB; Department of Neurology, University of Utah School of Medicine, Salt Lake City., Glass JD; Department of Neurology, Emory University School of Medicine, Atlanta, Georgia., Hardy J; Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom., Harms MB; Department of Neurology, Columbia University, New York, New York., Heiman-Patterson TD; Department of Neurology, Drexel University College of Medicine, Philadelphia, Pennsylvania.; Department of Neurology, Temple University, Philadelphia, Pennsylvania., Hernandez DG; Genomics Technology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Jansson L; Department of Neurology, University of Helsinki, Helsinki, Finland., Kirby J; Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom., Kowall NW; Department of Neurology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts., Laaksovirta H; Department of Neurology, University of Helsinki, Helsinki, Finland., Landeck N; Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Landi F; Department of Geriatrics, Neurosciences and Orthopedics, Center for Geriatric Medicine, Catholic University of Sacred Heart, Rome, Italy., Le Ber I; Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière, Université Pierre et Marie Curie, Paris, France.; INSERM U975, Paris, France., Lumbroso S; INM, INSERM, University of Montpellier, CHU Nîmes, Nîmes, France., MacGowan DJL; Neuromuscular Division and ALS Center, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, New York., Maragakis NJ; Department of Neurology, Johns Hopkins University, Baltimore, Maryland., Mora G; ALS Center, ICS Maugeri, IRCCS, Milan, Italy., Mouzat K; INM, INSERM, University of Montpellier, CHU Nîmes, Nîmes, France., Murphy NA; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Myllykangas L; Department of Pathology, Haartman Institute/HUSLAB, University of Helsinki and Folkhalsan Research Center (LM), Helsinki, Finland., Nalls MA; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland.; Data Tecnica International, Glen Echo, Maryland., Orrell RW; Department of Clinical Neuroscience, Institute of Neurology, University College London, London, United Kingdom., Ostrow LW; Department of Neurology, Johns Hopkins University, Baltimore, Maryland., Pamphlett R; Discipline of Pathology, Brain and Mind Centre, University of Sydney, Camperdown, Australia., Pickering-Brown S; Faculty of Human and Medical Sciences, University of Manchester, Manchester, United Kingdom., Pioro EP; Department of Neurology, Cleveland Clinic, Cleveland, Ohio., Pletnikova O; Clinical and Neuropathology Core, Johns Hopkins University, Baltimore, Maryland., Pliner HA; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Pulst SM; Department of Neurology, University of Utah School of Medicine, Salt Lake City., Ravits JM; Department of Neuroscience, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, University of California San Diego, La Jolla., Renton AE; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland.; Nash Family Department of Neuroscience, Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York., Rivera A; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Robberecht W; Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, University of Leuven, Leuven, Belgium., Rogaeva E; Tanz Centre for Research of Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada., Rollinson S; Faculty of Human and Medical Sciences, University of Manchester, Manchester, United Kingdom., Rothstein JD; Department of Neurology, Johns Hopkins University, Baltimore, Maryland., Scholz SW; Neurodegenerative Diseases Research Unit, Laboratory of Neurogenetics, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland.; Department of Neurology, Johns Hopkins University, Baltimore, Maryland., Sendtner M; Department of Neurology, Institute for Clinical Neurobiology, University of Würzburg, Würzburg, Germany., Shaw PJ; Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom., Sidle KC; Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom., Simmons Z; Department of Neurology, Penn State College of Medicine, Hershey, Pennsylvania., Singleton AB; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Smith N; Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland., Stone DJ; Department of Genetics and Pharmacogenomics, Merck Research Laboratories, Merck, West Point, Pennsylvania., Tienari PJ; Department of Neurology, University of Helsinki, Helsinki, Finland., Troncoso JC; Clinical and Neuropathology Core, Johns Hopkins University, Baltimore, Maryland., Valori M; Department of Neurology, University of Helsinki, Helsinki, Finland., Van Damme P; Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, University of Leuven, Leuven, Belgium.; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, University of Leuven, Leuven, Belgium., Van Deerlin VM; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia., Van Den Bosch L; Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, University of Leuven, Leuven, Belgium., Zinman L; Division of Neurology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada., Landers JE; Department of Neurology, University of Massachusetts Medical School, Worcester., Chiò A; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Neuroscience Institute of Torino, University of Turin, Turin, Italy., Traynor BJ; Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland.; Department of Molecular Neuroscience and Reta Lila Weston Laboratories, Institute of Neurology, University College London, London, United Kingdom.; Department of Neurology, Johns Hopkins University, Baltimore, Maryland.; National Institute of Neurological Disorders and Stroke, Bethesda, Maryland., Angelocola SM; Neurology Unit, AV4 ASUR Marche, Fermo, Italy., Ausiello FP; Neuroscience Institute of Torino, University of Turin, Turin, Italy., Barberis M; Department of Medical Genetic, Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Torino, Italy., Bartolomei I; Center for Diagnosis and Cure of Rare Diseases, Department of Neurology, IRCCS Institute of Neurological Sciences, Bologna, Italy., Battistini S; Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy., Bersano E; 3rd Neurology Unit and Motor Neuron Diseases Centre, IRCCS Foundation 'Carlo Besta' Neurological Institute, Milan, Italy., Bisogni G; NeuroMuscular Omnicentre (NEMO), Serena Onlus, Foundation Pol. A. Gemelli, Roma, Italy., Borghero G; Neurologic Unit, Monserrato University Hospital, Cagliari University, Cagliari, Italy., Brunetti M; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Cabona C; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal-Child Sciences, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Calvo A; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Division of Neurology, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Italy., Canale F; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli,' Caserta, Italy., Canosa A; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Division of Neurology, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Italy., Cantisani TA; Struttura complessa di Neurofisiopatologia, Azienda Ospedaliera di Perugia, Perugia, Italy., Capasso M; Unit of Neurology, Ospedale Clinicizzato SS Annunziata, Chieti, Italy., Caponnetto C; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal-Child Sciences, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Cardinali P; Neurology Unit, AV4 ASUR Marche, Fermo, Italy., Carrera P; Unit of Genomics for the Diagnosis of Human Pathologies, IRCCS San Raffaele Scientific Institute, Milan, Italy., Casale F; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Chiò A; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Division of Neurology, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Italy., Colletti T; ALS Clinical Research Center, BiND, University of Palermo, Palermo, Italy., Conforti FL; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy., Conte A; NeuroMuscular Omnicentre (NEMO), Serena Onlus, Foundation Pol. A. Gemelli, Roma, Italy., Conti E; Neurology Unit, 'San Gerardo' Hospital, Monza, Italy.; School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milan, Italy., Corbo M; Department of Neurorehabilitation Sciences, Casa Cura Policlinico, Milan, Italy., Cuccu S; Neurologic Unit, Monserrato University Hospital, Cagliari University, Cagliari, Italy., Dalla Bella E; 3rd Neurology Unit and Motor Neuron Diseases Centre, IRCCS Foundation 'Carlo Besta' Neurological Institute, Milan, Italy., D'Errico E; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari 'Aldo Moro,' Policlinic, Bari, Italy., DeMarco G; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Dubbioso R; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Napoli, Italy., Ferrarese C; Neurology Unit, 'San Gerardo' Hospital, Monza, Italy.; School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milan, Italy., Ferraro PM; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal-Child Sciences, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Filippi M; Neurology Unit and Rehabilitation Unit, IRCCS 'San Raffaele Scientific Institute,' Milan, Italy.; Neuroimaging Research Unit, Division of Neuroscience, IRCCS 'San Raffaele Scientific Institute,' Milan, Italy.; Neurophysiology Service, IRCCS 'San Raffaele Scientific Institute,' Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Fini N; Department of Neurosciences, Ospedale Civile S. Agostino Estense, Azienda Ospedaliero Universitaria di Modena, Modena, Italy., Floris G; Neurologic Unit, Monserrato University Hospital, Cagliari University, Cagliari, Italy., Fuda G; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Gallone S; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Gianferrari G; Department of Neurosciences, Ospedale Civile S. Agostino Estense, Azienda Ospedaliero Universitaria di Modena, Modena, Italy., Giannini F; Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy., Grassano M; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Greco L; NeuroMuscular Omnicentre (NEMO) Clinical Center Milano, Fondazione Serena Onlus, Milan, Italy., Iazzolino B; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Introna A; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari 'Aldo Moro,' Policlinic, Bari, Italy., La Bella V; ALS Clinical Research Center, BiND, University of Palermo, Palermo, Italy., Lattante S; Genetica Medica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.; Dipartimento Universitario Scienze della Vita e Sanità Pubblica, Sezione di Medicina Genomica, Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia, Roma, Italy., Lauria G; 3rd Neurology Unit and Motor Neuron Diseases Centre, IRCCS Foundation 'Carlo Besta' Neurological Institute, Milan, Italy.; Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy., Liguori R; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Logroscino G; Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.; Center for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, Pia Fondazione Cardinale G. Panico, Tricase, Italy., Logullo FO; Neurology Unit, AV3, ASUR Marche, Macerata, Italy., Lunetta C; NeuroMuscular Omnicentre (NEMO) Clinical Center Milano, Fondazione Serena Onlus, Milan, Italy., Mandich P; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal-Child Sciences, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Medical Genetics Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Mandrioli J; Department of Neurosciences, Ospedale Civile S. Agostino Estense, Azienda Ospedaliero Universitaria di Modena, Modena, Italy., Manera U; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Manganelli F; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Napoli, Italy., Marangi G; Genetica Medica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.; Dipartimento Universitario Scienze della Vita e Sanità Pubblica, Sezione di Medicina Genomica, Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia, Roma, Italy., Marinou K; Department of Neurorehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Milan, Milan, Italy., Marrosu MG; Department of Neurology, Azienda Universitario Ospedaliera di Cagliari and University of Cagliari, Cagliari, Italy., Martinelli I; Department of Neurosciences, Ospedale Civile S. Agostino Estense, Azienda Ospedaliero Universitaria di Modena, Modena, Italy., Messina S; NeuroMuscular Omnicentre (NEMO) Sud, Fondazione Aurora, OUC Neurology and Neuromuscular Disorders, University of Messina, Messina, Italy., Moglia C; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy.; Division of Neurology, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Italy., Mora G; Department of Neurorehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Milan, Milan, Italy., Mosca L; Department of Laboratory Medicine, Medical Genetics, Niguarda Ca' Granda Hospital, Milan, Italy., Murru MR; Neurologic Unit, Monserrato University Hospital, Cagliari University, Cagliari, Italy., Origone P; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal-Child Sciences, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Passaniti C; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli,' Napoli, Italy., Petrelli C; Neurology Unit, AV3, ASUR Marche, Macerata, Italy., Petrucci A; Neurology Department, San Camillo Hospital, Roma, Italy., Pozzi S; NeuroMuscular Omnicentre (NEMO) Clinical Center Milano, Fondazione Serena Onlus, Milan, Italy., Pugliatti M; Department of Biomedical and Surgical Sciences, Section of Neurological, Psychiatric and Psychological Sciences, University of Ferrara, Ferrara, Italy., Quattrini A; Department of Neurology, IRCCS 'San Raffaele Scientific Institute,' Milan, Italy., Ricci C; Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy., Riolo G; Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy., Riva N; Department of Neurology, IRCCS 'San Raffaele Scientific Institute,' Milan, Italy., Russo M; OUC Neurology and Neuromuscular Disorders, University of Messina, Messina, Italy., Sabatelli M; NeuroMuscular Omnicentre (NEMO)-Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Roma, Italy., Salamone P; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Salivetto M; NeuroMuscular Omnicentre (NEMO) Clinical Center Milano, Fondazione Serena Onlus, Milan, Italy., Salvi F; Center for Diagnosis and Cure of Rare Diseases, Department of Neurology, IRCCS Institute of Neurological Sciences, Bologna, Italy., Santarelli M; Department of Medicine, Azienda Complesso Ospedaliero, San Filippo Neri, Roma, Italy., Sbaiz L; Department of Medical Genetic, Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Torino, Italy., Sideri R; Department of Neurorehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Milan, Milan, Italy., Simone I; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari 'Aldo Moro,' Policlinic, Bari, Italy., Simonini C; Department of Neurosciences, Ospedale Civile S. Agostino Estense, Azienda Ospedaliero Universitaria di Modena, Modena, Italy., Spataro R; ALS Clinical Research Center, BiND, University of Palermo, Palermo, Italy., Tanel R; Operative Unit of Neurology, S. Chiara Hospital, Trento, Italy., Tedeschi G; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli,' Napoli, Italy., Ticca A; Department of Neurology, Azienda Ospedaliera San Francesco, Nuoro, Italy., Torriello A; ALS Center, Operative Unit of Neurology, AOU 'San Giovanni di Dio e Ruggi d'Aragona,' Salerno, Italy., Tranquilli S; Neurologic Unit, Monserrato University Hospital, Cagliari University, Cagliari, Italy., Tremolizzo L; Neurology Unit, 'San Gerardo' Hospital, Monza, Italy.; School of Medicine and Surgery and Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milan, Italy., Trojsi F; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli,' Napoli, Italy., Vasta R; 'Rita Levi Montalcini' Department of Neuroscience, University of Turin, Turin, Italy., Vacchiano V; Center for Diagnosis and Cure of Rare Diseases, Department of Neurology, IRCCS Institute of Neurological Sciences, Bologna, Italy., Vita G; OUC Neurology and Neuromuscular Disorders, University of Messina, Messina, Italy., Volanti P; Neurorehabilitation Unit-ALS Center, Istituti Clinici Scientifici (ICS) Maugeri, Mistretta, Italy., Zollino M; Sezione di Medicina Genomica, Dipartimento Scienze della Vita e Sanità Pubblica, Facoltà di Medicina e Chirurgia, Università Cattolica Sacro Cuore, Roma, Italy.; Unità di Genetica Medica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy., Zucchi E; Department of Neurosciences, Ospedale Civile S. Agostino Estense, Azienda Ospedaliero Universitaria di Modena, Modena, Italy.
Publikováno v:
JAMA neurology [JAMA Neurol] 2021 Oct 01; Vol. 78 (10), pp. 1236-1248.
Autor:
Satizabal CL; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA. satizabal@uthscsa.edu.; Department of Population Health Sciences, UT Health San Antonio, San Antonio, TX, USA. satizabal@uthscsa.edu.; The Framingham Heart Study, Framingham, MA, USA. satizabal@uthscsa.edu.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA. satizabal@uthscsa.edu., Adams HHH; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands.; Department of Clinical Genetics, Erasmus MC, Rotterdam, the Netherlands., Hibar DP; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., White CC; Cell Circuits Program, Broad Institute, Cambridge, MA, USA.; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA., Knol MJ; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Stein JL; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; UNC Neuroscience Center, University of North Carolina, Chapel Hill, NC, USA., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE: The Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Sargurupremraj M; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, Team VINTAGE, UMR 1219, Bordeaux, France., Jahanshad N; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Roshchupkin GV; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands.; Department of Medical Informatics, Erasmus MC, Rotterdam, the Netherlands., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Jian X; The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Luciano M; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., van der Lee SJ; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Yang J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Yanek LR; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lee TV; Department of Neurology, Baylor College of Medicine, Houston, TX, USA., Li S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Hu Y; Department of Genetics, Harvard Medical School, Boston, MA, USA., Koh JY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Eicher JD; Division of Intramural Research, Population Sciences Branch, National Heart, Lung and Blood Institute, Framingham, MA, USA., Desrivières S; MRC-SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Arias-Vasquez A; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Chauhan G; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, Team VINTAGE, UMR 1219, Bordeaux, France.; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Athanasiu L; CoE NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Rentería ME; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Kim S; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Neuroimaging, Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA., Hoehn D; Max Planck Institute of Psychiatry, Munich, Germany., Armstrong NJ; Mathematics and Statistics, Murdoch University, Perth, Western Australia, Australia., Chen Q; Lieber Institute for Brain Development, Baltimore, MD, USA., Holmes AJ; Department of Psychology, Yale University, New Haven, CT, USA.; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., den Braber A; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, VU Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., Kloszewska I; Medical University of Lodz, Lodz, Poland., Andersson M; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden.; Umeå Centre for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden., Espeseth T; CoE NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Psychology, University of Oslo, Oslo, Norway., Grimm O; Central Institute of Mental Health, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany., Abramovic L; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Alhusaini S; The Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Neurology, Yale School of Medicine, New Haven, CT, USA., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands., Papmeyer M; Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK.; Division of Systems Neuroscience of Psychopathology, Translational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland., Axelsson T; Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Ehrlich S; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Dresden, Germany.; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA., Roiz-Santiañez R; Department of Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, Santander, Spain.; Department of Medicine, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, Santander, Spain.; Centro Investigación Biomédica en Red Salud Mental, Santander, Spain., Kraemer B; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University, Heidelberg, Germany., Håberg AK; Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Radiology, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Jones HJ; Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK.; NIHR Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, UK., Pike GB; Department of Radiology, University of Calgary, Calgary, Alberta, Canada.; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada., Stein DJ; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.; South African Medical Research Council Unit on Risk and Resilience in Mental Disorders, Cape Town, South Africa., Stevens A; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA., Bralten J; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Vernooij MW; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA., Filippi I; INSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Saclay University and Paris Descartes University-DIGITEO Labs, Gif sur Yvette, France., Witte AV; Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.; Faculty of Medicine, CRC 1052 'Obesity Mechanisms', University of Leipzig, Leipzig, Germany., Guadalupe T; International Max Planck Research School for Language Sciences, Nijmegen, the Netherlands.; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands., Wittfeld K; Department of Psychiatry, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases, Greifswald, Germany., Mosley TH; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Becker JT; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Doan NT; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Hagenaars SP; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Saba Y; Research Unit-Genetic Epidemiology, Gottfried Schatz Research Centre for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Cuellar-Partida G; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Amin N; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Hilal S; Department of Pharmacology, National University of Singapore, Singapore, Singapore.; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore., Nho K; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Neuroimaging, Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA., Mirza-Schreiber N; Max Planck Institute of Psychiatry, Munich, Germany.; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany., Arfanakis K; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA.; Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL, USA., Becker DM; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ames D; Academic Unit for Psychiatry of Old Age, University of Melbourne, Melbourne, Victoria, Australia.; National Ageing Research Institute, Royal Melbourne Hospital, Melbourne, Victoria, Australia., Goldman AL; Lieber Institute for Brain Development, Baltimore, MD, USA., Lee PH; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Lurie Center for Autism, Massachusetts General Hospital, Harvard Medical School, Lexington, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands., Lovestone S; Department of Psychiatry, University of Oxford, Oxford, UK.; NIHR Dementia Biomedical Research Unit, King's College London, London, UK., Giddaluru S; NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.; Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Le Hellard S; NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.; Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Mattheisen M; Centre for integrated Sequencing, Aarhus University, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.; Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden., Bohlken MM; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Kasperaviciute D; UCL Queen Square Institute of Neurology, London, UK.; Chalfont Centre for Epilepsy, Bucks, UK., Schmaal L; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia.; Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Victoria, Australia., Lawrie SM; Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK., Agartz I; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden.; Department of Research and Development, Diakonhjemmet Hospital, Oslo, Norway., Walton E; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Dresden, Germany.; Department of Psychology, University of Bath, Bath, UK., Tordesillas-Gutierrez D; Centro Investigación Biomédica en Red Salud Mental, Santander, Spain.; Neuroimaging Unit, Technological Facilities, Valdecilla Biomedical Research Institute IDIVAL, Santander, Spain., Davies GE; Avera Institute for Human Genetics, Sioux Falls, SD, USA., Shin J; Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Ipser JC; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa., Vinke LN; Center for Systems Neuroscience, Boston University, Boston, MA, USA., Hoogman M; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Jia T; MRC-SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Burkhardt R; LIFE: The Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany., Klein M; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Crivello F; Neurodegeneratives Diseases Institute, CNRS UMR 5293, Université de Bordeaux, Bordeaux, France., Janowitz D; Department of Psychiatry, University Medicine Greifswald, Greifswald, Germany., Carmichael O; Pennington Biomedical Research Center, Baton Rouge, LA, USA., Haukvik UK; CoE NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Adult Psychiatry, Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Aribisala BS; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Department of Computer Science, Lagos State University, Ojo, Nigeria., Schmidt H; Research Unit-Genetic Epidemiology, Gottfried Schatz Research Centre for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Strike LT; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Risacher SL; Center for Neuroimaging, Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA., Pütz B; Max Planck Institute of Psychiatry, Munich, Germany., Fleischman DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA., Assareh AA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia., Mattay VS; Lieber Institute for Brain Development, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Buckner RL; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychology, Center for Brain Science, Harvard University, Cambridge, MA, USA., Mecocci P; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy., Dale AM; Center for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, USA.; Department of Cognitive Sciences, University of California, San Diego, San Diego, CA, USA.; Department of Neurosciences, University of California. San Diego, San Diego, CA, USA.; Department of Psychiatry, University of California, San Diego, San Diego, CA, USA.; Department of Radiology, University of California, San Diego, San Diego, CA, USA., Cichon S; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Institute for Neuroscience and Medicine: Structural and Functional Organisation of the Brain (INM-1), Research Centre Jülich, Jülich, Germany., Boks MP; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Matarin M; UCL Queen Square Institute of Neurology, London, UK.; Reta Lila Weston Institute, UCL Institute of Neurology, London, UK.; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands., Calhoun VD; Department of ECE, University of New Mexico, Albuquerque, NM, USA.; The Mind Research Network and LBERI, Albuquerque, NM, USA.; Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Atlanta, GA, USA., Chakravarty MM; Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, Québec, Canada.; Departments of Psychiatry and Biological and Biomedical Engineering, McGill University, Montreal, Québec, Canada., Marquand AF; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Donders Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, the Netherlands., Macare C; MRC-SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Kharabian Masouleh S; Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.; Institute for Neuroscience and Medicine: Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany., Oosterlaan J; Clinical Neuropsychology Section, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Emma Neuroscience Group, Department of Pediatrics, Emma Children's Hospital, Amsterdam Reproduction & Development, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Amouyel P; LabEx DISTALZ-U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, University of Lille, Lille, France.; Inserm U1167, Lille, France.; Centre Hospitalier Universitaire Lille, Lille, France.; Institut Pasteur de Lille, Lille, France., Hegenscheid K; Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, USA., Schork AJ; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Roskilde, Denmark.; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA., Liewald DCM; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., de Zubicaray GI; Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Academic Medicine Research Institute, Duke-NUS Medical School, Singapore, Singapore., Shen L; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA., Sämann PG; Max Planck Institute of Psychiatry, Munich, Germany., Brodaty H; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Dementia Centre for Research Collaboration, UNSW, Sydney, New South Wales, Australia., Roffman JL; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., de Geus EJC; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands., Tsolaki M; 1st Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Erk S; Division of Mind and Brain Research, D, Corporate member of Freie Universität Berliepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany., van Eijk KR; Brain Center Rudolf Magnus, Human Neurogenetics Unit, UMC Utrecht, Utrecht, the Netherlands., Cavalleri GL; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., van der Wee NJA; Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.; Leiden Institute for Brain and Cognition, Leiden University Medical Center, Leiden, the Netherlands., McIntosh AM; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK., Gollub RL; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.; Harvard Medical School, Boston, MA, USA., Bulayeva KB; Department of Evolution and Genetics, Dagestan State University, Makhachkala, Russia., Bernard M; Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Richards JS; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; University Medical Center Groningen, Department of Psychiatry, University of Groningen, Groningen, the Netherlands., Himali JJ; The Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE: The Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Rommelse N; Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Karakter Child and Adolescent Psychiatry University Center, Nijmegen, the Netherlands., Hoffmann W; German Center for Neurodegenerative Diseases, Greifswald, Germany.; Section Epidemiology of Health Care and Community Health, Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Westlye LT; CoE NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Valdés Hernández MC; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Hansell NK; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., van Erp TGM; Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USA.; Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA, USA., Wolf C; Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany., Kwok JBJ; Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia.; Neuroscience Research Australia, Sydney, New South Wales, Australia.; University of New South Wales, Sydney, New South Wales, Australia., Vellas B; Department of Internal Medicine, INSERM U 1027, University of Toulouse, Toulouse, France.; Department of Geriatric Medicine, INSERM U 1027, University of Toulouse, Toulouse, France., Heinz A; Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany., Olde Loohuis LM; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Delanty N; The Royal College of Surgeons in Ireland, Dublin, Ireland.; Neurology Division, Beaumont Hospital, Dublin, Ireland., Ho BC; Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Ching CRK; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Interdepartmental Neuroscience Graduate Program, UCLA School of Medicine, Los Angeles, CA, USA., Shumskaya E; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Donders Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, the Netherlands., Singh B; Imaging of Dementia and Aging Laboratory, Department of Neurology, University of California, Davis, Davis, CA, USA., Hofman A; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., van der Meer D; CoE NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Kaiser Permanent Washington Health Research Institute, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Bastin ME; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Montgomery GW; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia., Foroud TM; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Reppermund S; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Department of Developmental Disability Neuropsychiatry, School of Psychiatry, UNSW Medicine, Sydney, New South Wales, Australia., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands., Simmons A; Biomedical Research Unit for Dementia, King's College London, London, UK.; Department of Neuroimaging, Institute of Psychiatry, King's College London, London, UK.; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden., Meyer-Lindenberg A; Central Institute of Mental Health, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany., Cahn W; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Whelan CD; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; The Royal College of Surgeons in Ireland, Dublin, Ireland., van Donkelaar MMJ; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Hosten N; Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany., Green RC; Harvard Medical School, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Thalamuthu A; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia., Mohnke S; Division of Mind and Brain Research, D, Corporate member of Freie Universität Berliepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany., Hulshoff Pol HE; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Lin H; The Framingham Heart Study, Framingham, MA, USA.; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Jack CR Jr; Department of Radiology, Mayo Clinic, Rochester, MN, USA., Schofield PR; Neuroscience Research Australia, Sydney, New South Wales, Australia.; School of Medical Sciences, UNSW, Sydney, New South Wales, Australia., Mühleisen TW; Institute for Neuroscience and Medicine: Structural and Functional Organisation of the Brain (INM-1), Research Centre Jülich, Jülich, Germany.; Department of Biomedicine, University of Basel, Basel, Switzerland.; Cécile and Oskar Vogt Institute for Brain Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Maillard P; Imaging of Dementia and Aging Laboratory, Department of Neurology, University of California, Davis, Davis, CA, USA., Potkin SG; Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USA., Wen W; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia., Fletcher E; Imaging of Dementia and Aging Laboratory, Department of Neurology, University of California, Davis, Davis, CA, USA., Toga AW; Laboratory of Neuro Imaging, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Gruber O; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University, Heidelberg, Germany., Huentelman M; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA., Davey Smith G; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD, USA., Nyberg L; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden.; Umeå Centre for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden.; Radiation Sciences, Umeå University, Umeå, Sweden., Jönsson EG; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden., Crespo-Facorro B; Department of Medicine, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, Santander, Spain.; Centro Investigación Biomédica en Red Salud Mental, Santander, Spain., Koen N; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.; South African Medical Research Council Unit on Risk and Resilience in Mental Disorders, Cape Town, South Africa., Greve DN; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Uitterlinden AG; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Weinberger DR; Lieber Institute for Brain Development, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Steen VM; NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.; Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Fedko IO; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands., Groenewold NA; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa., Niessen WJ; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands.; Department of Medical Informatics, Erasmus MC, Rotterdam, the Netherlands.; Imaging Physics, Faculty of Applied Sciences, Delft University of Technology, Delft, the Netherlands., Toro R; Institut Pasteur, Paris, France., Tzourio C; Department of Neurology, CHU de Bordeaux, Bordeaux, France., Longstreth WT Jr; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Neurology, University of Washington, Seattle, WA, USA., Ikram MK; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Neurology, Erasmus MC, Rotterdam, the Netherlands., Smoller JW; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA., van Tol MJ; Cognitive Neuroscience Center, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Sussmann JE; Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK., Paus T; Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada.; Department of Psychology, University of Toronto, Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada., Lemaître H; INSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Saclay University and Paris Descartes University-DIGITEO Labs, Gif sur Yvette, France., Schroeter ML; LIFE: The Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.; Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.; Clinic for Cognitive Neurology, University Clinic Leipzig, Leipzig, Germany., Mazoyer B; Neurodegeneratives Diseases Institute, CNRS UMR 5293, Université de Bordeaux, Bordeaux, France., Andreassen OA; CoE NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Holsboer F; Max Planck Institute of Psychiatry, Munich, Germany.; HMNC Brain Health, Munich, Germany., Depondt C; Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium., Veltman DJ; Department of Psychiatry, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands., Turner JA; The Mind Research Network and LBERI, Albuquerque, NM, USA.; Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Atlanta, GA, USA.; Department of Psychology, Georgia State University, Atlanta, GA, USA., Pausova Z; Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Schumann G; MRC-SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., van Rooij D; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; University Medical Center Groningen, Department of Psychiatry, University of Groningen, Groningen, the Netherlands., Djurovic S; NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Deary IJ; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., McMahon KL; Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., Müller-Myhsok B; Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, UK., Brouwer RM; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Soininen H; Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland.; Neurocentre Neurology, Kuopio University Hospital, Kuopio, Finland., Pandolfo M; Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium., Wassink TH; Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Cheung JW; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Wolfers T; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Martinot JL; INSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Saclay University and Paris Descartes University-DIGITEO Labs, Gif sur Yvette, France., Zwiers MP; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Donders Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, the Netherlands., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.; German Center for Cardiovascular Research (partner site Greifswald), Greifswald, Germany., Melle I; CoE NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; CoE NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Kanai R; Department of Neuroinformatics, Araya, Tokyo, Japan.; Institute of Cognitive Neuroscience, University College London, London, UK.; School of Psychology, University of Sussex, Brighton, UK., Westman E; Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Kahn RS; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sisodiya SM; UCL Queen Square Institute of Neurology, London, UK.; Chalfont Centre for Epilepsy, Bucks, UK., White T; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands.; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands., Saremi A; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., van Bokhoven H; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Brunner HG; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands.; GROW School for Oncology and Developmental Biology, Maastricht, the Netherlands., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; German Center for Cardiovascular Research (partner site Greifswald), Greifswald, Germany., Wright MJ; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia., van 't Ent D; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany., Ophoff RA; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands., Buitelaar JK; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Karakter Child and Adolescent Psychiatry University Center, Nijmegen, the Netherlands., Fernández G; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Sachdev PS; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, New South Wales, Australia., Rietschel M; Central Institute of Mental Health, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany., van Haren NEM; Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands., Fisher SE; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands., Beiser AS; The Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Francks C; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands., Saykin AJ; Center for Neuroimaging, Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Neuroscience Research Australia, Sydney, New South Wales, Australia., Romanczuk-Seiferth N; Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany., Hartman CA; University Medical Center Groningen, Department of Psychiatry, University of Groningen, Groningen, the Netherlands., DeStefano AL; The Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Heslenfeld DJ; Department of Psychology, VU University Amsterdam, Amsterdam, the Netherlands., Weiner MW; Center for Imaging of Neurodegenerative Disease, San Francisco VA Medical Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA., Walter H; Division of Mind and Brain Research, D, Corporate member of Freie Universität Berliepartment of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany., Hoekstra PJ; University Medical Center Groningen, Department of Psychiatry, University of Groningen, Groningen, the Netherlands., Nyquist PA; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Franke B; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA., Grabe HJ; Department of Psychiatry, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases, Greifswald, Germany., Johnson AD; Division of Intramural Research, Population Sciences Branch, National Heart, Lung and Blood Institute, Framingham, MA, USA., Chen C; Department of Pharmacology, National University of Singapore, Singapore, Singapore.; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore., van Duijn CM; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Lopez OL; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Fornage M; The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Wardlaw JM; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., DeCarli C; Department of Neurology, Center for Neuroscience, University of California, Davis, Sacramento, CA, USA., De Jager PL; Cell Circuits Program, Broad Institute, Cambridge, MA, USA.; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA., Villringer A; Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.; Faculty of Medicine, CRC 1052 'Obesity Mechanisms', University of Leipzig, Leipzig, Germany., Debette S; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, Team VINTAGE, UMR 1219, Bordeaux, France.; Department of Neurology, CHU de Bordeaux, Bordeaux, France., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Shulman JM; Department of Neurology, Baylor College of Medicine, Houston, TX, USA.; Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA., Thompson PM; Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Seshadri S; The Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Ikram MA; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands. m.a.ikram@erasmusmc.nl.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands. m.a.ikram@erasmusmc.nl.
Publikováno v:
Nature genetics [Nat Genet] 2019 Nov; Vol. 51 (11), pp. 1624-1636. Date of Electronic Publication: 2019 Oct 21.