Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ei-Wen Yang"'
Autor:
Ei-Wen Yang, Jae Hoon Bahn, Esther Yun-Hua Hsiao, Boon Xin Tan, Yiwei Sun, Ting Fu, Bo Zhou, Eric L. Van Nostrand, Gabriel A. Pratt, Peter Freese, Xintao Wei, Giovanni Quinones-Valdez, Alexander E. Urban, Brenton R. Graveley, Christopher B. Burge, Gene W. Yeo, Xinshu Xiao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Differential binding of RNA-binding proteins mediated by genetic variants (GVs) can influence posttranscriptional regulation. Here, the authors develop BEAPR, a computational approach to identify allele-specific binding events in eCLIP-Seq data.
Externí odkaz:
https://doaj.org/article/40fe4f1d191643449b3e71a16d4eeda4
Autor:
Keng-Chang Tsai, Jhih-Wei Jian, Ei-Wen Yang, Po-Chiang Hsu, Hung-Pin Peng, Ching-Tai Chen, Jun-Bo Chen, Jeng-Yih Chang, Wen-Lian Hsu, An-Suei Yang
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40846 (2012)
Non-covalent protein-carbohydrate interactions mediate molecular targeting in many biological processes. Prediction of non-covalent carbohydrate binding sites on protein surfaces not only provides insights into the functions of the query proteins; in
Externí odkaz:
https://doaj.org/article/eff72ec64cd84cddb9410638c9f4613c
Autor:
Ching-Tai Chen, Hung-Pin Peng, Jhih-Wei Jian, Keng-Chang Tsai, Jeng-Yih Chang, Ei-Wen Yang, Jun-Bo Chen, Shinn-Ying Ho, Wen-Lian Hsu, An-Suei Yang
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37706 (2012)
Protein-protein interactions are key to many biological processes. Computational methodologies devised to predict protein-protein interaction (PPI) sites on protein surfaces are important tools in providing insights into the biological functions of p
Externí odkaz:
https://doaj.org/article/956ae916535b4e9cb341b709ada3d196
Autor:
Chung-Ming Yu, Hung-Pin Peng, Ing-Chien Chen, Yu-Ching Lee, Jun-Bo Chen, Keng-Chang Tsai, Ching-Tai Chen, Jeng-Yih Chang, Ei-Wen Yang, Po-Chiang Hsu, Jhih-Wei Jian, Hung-Ju Hsu, Hung-Ju Chang, Wen-Lian Hsu, Kai-Fa Huang, Alex Che Ma, An-Suei Yang
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33340 (2012)
Protein-protein interactions are critical determinants in biological systems. Engineered proteins binding to specific areas on protein surfaces could lead to therapeutics or diagnostics for treating diseases in humans. But designing epitope-specific
Externí odkaz:
https://doaj.org/article/edd7680d33c84d8898a3b06986ae60b4
Autor:
Yiwei Sun, Xinshu Xiao, Kofi Amoah, Jae Hoon Bahn, Christina P. Burghard, Yun-Hua Esther Hsiao, Ei-Wen Yang, Boon Xin Tan
Publikováno v:
Genome Res
Genome research, vol 31, iss 3
Genome research, vol 31, iss 3
Alternative splicing is an RNA processing mechanism that affects most genes in human, contributing to disease mechanisms and phenotypic diversity. The regulation of splicing involves an intricate network of cis-regulatory elements and trans-acting fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44b7ad92c76245f94ffd13a815b727a
https://doi.org/10.1101/gr.265637.120
https://doi.org/10.1101/gr.265637.120
Autor:
Yun-Hua Esther Hsiao, Boon Xin Tan, Xinshu Xiao, Kofi Amoah, Yiwei Sun, Christina P. Burghard, Jae Hoon Bahn, Ei-Wen Yang
Alternative splicing is an RNA processing mechanism that affects most genes in human, contributing to disease mechanisms and phenotypic diversity. The regulation of splicing involves an intricate network of cis-regulatory elements and trans-acting fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8fbb1dfdfbc9ca93369ac1bcde4d0b
Autor:
Matthew C. Valdez, Catherine Ho, Poonamjot Deol, Frances M. Sladek, Jack Reid, Holly Richardson, Jose Martinez-Lomeli, Ei-Wen Yang, Joseph Valdez, Margarita C. Currás-Collazo, Tao Jiang, Jane R. Evans, Edward Truong, Jonathan R. Deans, Elena V. Kozlova, Gwendolyn Gonzalez
Publikováno v:
Endocrinology
Soybean oil consumption has increased greatly in the past half-century and is linked to obesity and diabetes. To test the hypothesis that soybean oil diet alters hypothalamic gene expression in conjunction with metabolic phenotype, we performed RNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300fa5ce2f4f93b020ff120df86e8dc4
https://doi.org/10.1210/endocr/bqz044
https://doi.org/10.1210/endocr/bqz044
Autor:
Joe Valdez, Poonamjot Deol, Ei-Wen Yang, Margarita C. Currás-Collazo, Holly Richardson, Frances Sladek, Catherine Ho, Thu Kyaw, Matt Valdez, Tao Jiang, Elena V. Kozlova, Jane R. Evans, Jonathan R. Deans
Publikováno v:
Journal of the Endocrine Society
Soybean oil is a major component of the American diet and its increased consumption correlates positively with the prevalence of obesity and diabetes in the U.S. Our previous findings showed that a high fat diet (HFD) enriched in soybean oil, similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4ba40b2b1508f2e3dcc2e4eea457c8
https://doi.org/10.1210/js.2019-sun-101
https://doi.org/10.1210/js.2019-sun-101
Autor:
Peter Freese, Christopher B. Burge, Esther Yun-Hua Hsiao, Gabriel A. Pratt, Boon Xin Tan, Jae Hoon Bahn, Giovanni Quinones-Valdez, Xintao Wei, Ting Fu, Ei-Wen Yang, Brenton R. Graveley, Xinshu Xiao, Alexander E. Urban, Gene W. Yeo, Yiwei Sun, Bo Zhou, Eric L. Van Nostrand
Publikováno v:
Nature Communications
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Allele-specific protein-RNA binding is an essential aspect that may reveal functional genetic variants (GVs) mediating post-transcriptional regulation. Recently, genome-wide detection of in vivo binding of RNA-binding proteins is greatly facilitated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c559e13531bed9e6849e027bacbf6d
http://europepmc.org/articles/PMC6430814
http://europepmc.org/articles/PMC6430814
Autor:
Tao Jiang, Ei-Wen Yang
Publikováno v:
Bioinformatics. 32:3593-3602
Motivation: Differential transcript expression (DTE) analysis without predefined conditions is critical to biological studies. For example, it can be used to discover biomarkers to classify cancer samples into previously unknown subtypes such that be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6354d522033c84bba42899b125aa4f10
https://doi.org/10.1093/bioinformatics/btw513
https://doi.org/10.1093/bioinformatics/btw513