Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Ei-Ichi Takahashi"'
Autor:
Toshimi Kambe, Takeshi Ogawara, Hiroyuki Kyushiki, Takashi Ban, Yasuchika Yamamoto, Atsunori Ueyama, Hiroyuki Fukui, Akira Tanigami, Tsutomu Fujiwara, Tatsuya Yamashita, Masashi Niimi, Kouichi Ozaki, Ei-ichi Takahashi, Hidenori Tamanoi, Takashi Okamoto
Publikováno v:
Journal of Human Genetics. 46:566-571
Glutamine:fructose-6-phosphate amidotransferase (GFAT1) is the rate-limiting enzyme in the hexosamine biosynthetic pathway, which plays an important role in hyperglycemia-induced insulin resistance. To evaluate the role of GFAT1 expression, we analyz
Autor:
Takao Namikawa, Takeshi Watanabe, Ei-ichi Takahashi, Asato Kuroiwa, Haretsugu Hishigaki, Kimiyuki Tsuchiya, Yoichi Matsuda
Publikováno v:
Chromosome Research. 9:61-67
We constructed the comparative cytogenetic maps of X chromosomes in three rodent species, Indian spiny mouse (Mus platythrix), Syrian hamster and Chinese hamster, using 26 mouse cDNA clones. Twenty-six, 22 and 22 out of the 26 genes, which were mappe
Autor:
Mikoto Yoshida, Eiji Abe, Mikio Suzuki, Ei Ichi Takahashi, Hidenori Terasaki, Kazuhiko Kuwahara, Yoshinobu Matsuo, Nobuo Sakaguchi
Publikováno v:
Gene. 255:219-227
A 210kDa protein named GANP is upregulated in germinal center (GC)-B cells in the spleen of antigen-immunized mouse. We studied a human ganp gene (hganp) encoding a putative polypeptide of 1980 amino acids. The carboxyl-terminal 721-amino-acid sequen
Autor:
Yusuke Nakamura, Toyoki Mori, Yoshihiro Taniguchi, Akira Tanigami, Masato Horie, Naohide Kanemoto, Akihito Watanabe, Naoki Nishino, Mari Kondo, Takashi Okamoto, Ei-ichi Takahashi, Hiroyuki Kyushiki, Yasuhide Mitsumoto, Koichi Noguchi
Publikováno v:
Genomics. 67:146-152
We have identified a novel mammalian gene, TMEFF2, that encodes a putative transmembrane protein containing two follistatin-like domains and one epidermal growth factor (EGF)-like domain. The TMEFF2 gene is predominantly expressed in the brain. In si
Autor:
Toshinori Ozaki, Miki Ohira, Shigeru Sakiyama, Mikio Suzuki, Akira Nakagawara, Eiji Hanaoka, Yohko Nakamura, Hideshige Moriya, Ei-ichi Takahashi
Publikováno v:
Journal of Human Genetics. 45:188-191
DA41 was previously identified as one of the DAN-binding proteins, via a yeast-based two-hybrid screening strategy. In the present study, we cloned a human homolog of DA41 cDNA. Structural analysis revealed that human DA41 cDNA consisted of 2,861 nuc
Autor:
Takashi Tokino, Chihiro Azuma, Yasuo Miyoshi, Mikio Suzuki, Yoshiki Takei, Yusuke Nakamura, Shigeyuki Isaka, Ei-ichi Takahashi, Yuji Murata, Kumiko Koyama
Publikováno v:
Genes, Chromosomes and Cancer. 27:345-352
Through a strategy of direct cloning of TP53-binding DNA sequences from human genome DNA, we have identified a novel TP53-target gene, termed TP53TG5 (TP53-target gene 5). This gene, localized to chromosome band 20q13.1 by fluorescence in situ hybrid
Autor:
Keiko Oga, Ayako Mizoguchi-Miyakita, Michael R. James, G. M. Lathrop, Toshihisa Takagi, Yusuke Nakamura, Ei Ichi Takahashi, Yasuo Irie, Naohide Kanemoto, Yuki Yamasaki, Takeshi K. Watanabe, M. T. Bihoreau, Haretsugu Hishigaki, Akira Tanigami, Shiro Okuno, Toshihide Ono
Publikováno v:
Mammalian Genome. 11:300-305
We have isolated more than 12,000 clones containing microsatellite sequences, mainly consisting of (CA)n dinucleotide repeats, using genomic DNA from the BN strain of laboratory rat. Data trimming yielded 9636 non-redundant microsatellite sequences,
Autor:
Keiji Terao, Yusuke Nakamura, Katsushi Tokunaga, Yumiko Suto, Ei-ichi Takahashi, Kumiko Koyama, Fumio Kasai, Momoki Hirai
Publikováno v:
Chromosome Research. 8:727-735
It is known that human chromosome 2 originated from the fusion of two ancestral primate chromosomes. This has been confirmed by chromosome banding and fluorescence in-situ hybridization (FISH) with human chromosome-2-specific DNA libraries. In this s
Autor:
Issay Kitabayashi, Nobuo Munakata, Naoko Mitsuhashi, Ei-ichi Takahashi, Fumiko Morohoshi, Mikio Suzuki, Sachiyo Mitani, Misao Ohki
Publikováno v:
Gene. 241:287-295
AML1-MTG8 fusion protein, which is produced from the rearranged gene formed between AML1 and MTG8 in myeloid leukemia with t(8;21) chromosomal translocation, plays an important role in the pathogenesis of leukemia. We previously showed that ectopical
Autor:
Hideo Miyao, Ei-ichi Takahashi, Yoshihiro Goto, Shiro Okuno, Toshihiro Asai, Toshihisa Takagi, Naohide Kanemoto, Takeshi K. Watanabe, Yusuke Nakamura, Akira Tanigami, Toshihide Ono, Yuki Yamasaki, Ayako Mizoguchi-Miyakita, Keiko Oga
Publikováno v:
Genomics. 62:350-355
Altered lipid metabolism is closely associated with diabetes in humans, although predisposing genetic factors that affect hyperlipidemia have not yet been clarified. Our previously established OLETF strain is an obese rat model of type II diabetes, e