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DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron  depletion.

Autor: Long M; Translational Stem Cell Biology & Metabolism Program, Research Programs Unit, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland., Sanchez-Martinez A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Longo M; MRC Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, The Sir James Black Centre, University of Dundee, Dundee, UK., Suomi F; Translational Stem Cell Biology & Metabolism Program, Research Programs Unit, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland., Stenlund H; Swedish Metabolomics Centre, Department of Plant Physiology, Umeå University, Umeå, Sweden., Johansson AI; Swedish Metabolomics Centre, Department of Plant Physiology, Umeå University, Umeå, Sweden., Ehsan H; Translational Stem Cell Biology & Metabolism Program, Research Programs Unit, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland., Salo VT; Translational Stem Cell Biology & Metabolism Program, Research Programs Unit, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.; Department of Anatomy, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Montava-Garriga L; MRC Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, The Sir James Black Centre, University of Dundee, Dundee, UK., Naddafi S; Translational Stem Cell Biology & Metabolism Program, Research Programs Unit, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland., Ikonen E; Translational Stem Cell Biology & Metabolism Program, Research Programs Unit, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.; Department of Anatomy, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Ganley IG; MRC Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, The Sir James Black Centre, University of Dundee, Dundee, UK., Whitworth AJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., McWilliams TG; Translational Stem Cell Biology & Metabolism Program, Research Programs Unit, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.; Department of Anatomy, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

Publikováno v: The EMBO journal [EMBO J] 2022 May 16; Vol. 41 (10), pp. e109390. Date of Electronic Publication: 2022 Apr 12.