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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

Autor: Liu, M, Jiang, Y, Wedow, R, Li, Y, Brazel, DM, Chen, F, Datta, G, Davila-Velderrain, J, McGuire, D, Tian, C, Zhan, X, Team, 23Andme Research, Psychiatry, Hunt All-In, Choquet, H, Docherty, AR, Faul, JD, Foerster, JR, Fritsche, LG, Gabrielsen, ME, Gordon, SD, Haessler, J, Hottenga, J-J, Huang, H, Jang, S-K, Jansen, PR, Ling, Y, Mägi, R, Matoba, N, McMahon, G, Mulas, A, Orrù, V, Palviainen, T, Pandit, A, Reginsson, GW, Skogholt, AH, Smith, JA, Taylor, AE, Turman, C, Willemsen, G, Young, H, Young, KA, Zajac, GJM, Zhao, W, Zhou, W, Bjornsdottir, G, Boardman, JD, Boehnke, M, Boomsma, DI, Chen, C, Cucca, F, Davies, GE, Eaton, CB, Ehringer, MA, Esko, T, Fiorillo, E, Gillespie, NA, Gudbjartsson, DF, Haller, T, Harris, KM, Heath, AC, Hewitt, JK, Hickie, IB, Hokanson, JE, Hopfer, CJ, Hunter, DJ, Iacono, WG, Johnson, EO, Kamatani, Y, Kardia, SLR, Keller, MC, Kellis, M, Kooperberg, C, Kraft, P, Krauter, KS, Laakso, M, Lind, PA, Loukola, A, Lutz, SM, Madden, PAF, Martin, NG, McGue, M, McQueen, MB, Medland, SE, Metspalu, A, Mohlke, KL, Nielsen, JB, Okada, Y, Peters, U, Polderman, TJC, Posthuma, D, Reiner, AP, Rice, JP, Rimm, E, Rose, RJ, Runarsdottir, V, Stallings, MC, Stančáková, A, Stefansson, H, Thai, KK, Tindle, HA, Tyrfingsson, T, Wall, TL, Weir, DR, Weisner, C, Whitfield, JB, Winsvold, BS, Yin, J, Zuccolo, L, Bierut, LJ, Hveem, K, Lee, JJ, Munafò, MR, Saccone, NL, Willer, CJ, Cornelis, MC, David, SP, Hinds, DA, Jorgenson, E, Kaprio, J, Stitzel, JA, Stefansson, K, Thorgeirsson, TE, Abecasis, G, Liu, DJ, Vrieze, S

Publikováno v: Liu, M, Jiang, Y, Wedow, R, Li, Y, Brazel, D M, Chen, F, Datta, G, Davila-Velderrain, J, McGuire, D, Tian, C, Zhan, X, Agee, M, Alipanahi, B, Auton, A, Bell, R K, Bryc, K, Elson, S L, Fontanillas, P, Furlotte, N A, Hinds, D A, Hromatka, B S, Huber, K E, Kleinman, A, Litterman, N K, McIntyre, M H, Mountain, J L, Northover, C A M, Sathirapongsasuti, J F, Sazonova, O V, Shelton, J F, Shringarpure, S, Tian, C, Tung, J Y, Vacic, V, Wilson, C H, Pitts, S J, Mitchell, A, Skogholt, A H, Winsvold, B S, Sivertsen, B R, Stordal, E, Morken, G, Kallestad, H V, Heuch, I, Zwart, J-A, Fjukstad, K K, Pedersen, L M, Gabrielsen, M E, Jansen, P R, Posthuma, D, 23andMe Research team, Jorgenson, E, Stitzel, J A, Liu, D J & Vrieze, S 2019, ' Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use ', Nature Genetics, vol. 51, no. 2, pp. 237-244 . https://doi.org/10.1038/s41588-018-0307-5
Nature Genetics
the 23 and Me Research Team 2019, ' Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use ', Nature Genetics, vol. 51, no. 2, pp. 237-244 . https://doi.org/10.1038/s41588-018-0307-5
Nature Genetics, 51(2), 237-244. Nature Publishing Group
Liu, M, Hottenga, J J, Jansen, P R, Willemsen, G, Boomsma, D I, Davies, G E, Polderman, T J C, Posthuma, D, Vrieze, S, 23Andme Research Team & HUNT All-In Psychiatry 2019, ' Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use ', Nature Genetics, vol. 51, no. 2, pp. 237-244 . https://doi.org/10.1038/s41588-018-0307-5
PMC
Nature genetics
Nature genetics, 51(2), 237-244. Nature Publishing Group

Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders1. They are heritable2,3 and etiologically related4,5 behaviors that have been resistant to gene discovery efforts6,7,8,9,10,11. In sam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f01e166190b1f57e8157a42854d232
https://research.vumc.nl/en/publications/d6127763-905e-44ae-88b1-ab80a1e7e269

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