Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas

Autor: Dawed, Adem Y., Yee, Sook Wah, Zhou, Kaixin, van Leeuwen, Nienke, Zhang, Yanfei, Siddiqui, Moneeza K., Etheridge, Amy, Innocenti, Federico, Xu, Fei, Li, Josephine H., Beulens, Joline W., van der Heijden, Amber A., Slieker, Roderick C., Chang, Yu-Chuan, Mercader, Josep M., Kaur, Varinderpal, Witte, John S., Lee, Ming Ta Michael, Kamatani, Yoichiro, Momozawa, Yukihide, Kubo, Michiaki, Palmer, Colin N.A., Florez, Jose C., Hedderson, Monique M., ‘t Hart, Leen M., Giacomini, Kathleen M., Pearson, Ewan R., Pearson, Ewan, Dawed, Adem, Holman, Rury, Coleman, Ruth, ‘t Hart, Leen, Slieker, Roderick, Beulens, Joline, van der Heijden, Amber, Nijpels, Giel, Elders, Petra, Rutters, Femke, Stricker, Bruno, Ahmadizar, Fariba, de Keyser, Catherine, Koov, Adriaan, Out, Mattijs, Kloviņš, Jānis, Zaharenko, Linda, Javorsky, Martin, Tkac, Ivan, Florez, Jose, Giacomini, Kathy, Wah Yee, Sook, Hedderson, Monique, Motsinger-Reif, Alison, Wagner, Michael, Semiz, Sabina, Dujic, Tanja, Christensen, Mette, Brøsen, Kim, Waterworth, Dawn, Ehm, Meg, Ma, Ronald, Psaty, Bruce, Floyd, James

Publikováno v: Diabetes Care, 44(12), 2673-2682. American Diabetes Association Inc.
Diabetes Care
for MetGen Plus, for the DIRECT Consortium 2021, ' Genome-wide meta-analysis identifies genetic variants associated with glycemic response to sulfonylureas ', Diabetes Care, vol. 44, no. 12, pp. 2673-2682 . https://doi.org/10.2337/dc21-1152

OBJECTIVE Sulfonylureas, the first available drugs for the management of type 2 diabetes, remain widely prescribed today. However, there exists significant variability in glycemic response to treatment. We aimed to establish heritability of sulfonylu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2540ec5a0eaa850e1220e1eb824477
https://doi.org/10.2337/dc21-1152

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