Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Ehirchiou, A."'
Autor:
Driss Ehirchiou, Ilaria Bernabei, Vishnuprabu Durairaj Pandian, Sonia Nasi, Veronique Chobaz, Mariela Castelblanco, Alexander So, Fabio Martinon, Xiaoyun Li, Hans Acha-Orbea, Thomas Hugle, Li Zhang, Nathalie Busso
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Objective In gout, monosodium urate crystals are taken up by macrophages, triggering the activation of the NLRP3 inflammasome and the maturation of IL-1β. This study aimed to investigate the role of integrin CD11b in inflammasome activation
Externí odkaz:
https://doaj.org/article/93a4fd0e67634a3ca322b72488f04249
Akademický článek
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Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104081- (2022)
Summary: Background: Cartilage damage in inflammatory arthritis is attributed to inflammatory cytokines and pannus infiltration. Activation of the coagulation system is a well known feature of arthritis, especially in rheumatoid arthritis (RA). Here
Externí odkaz:
https://doaj.org/article/bbf024a02dcc40d0a14c8daac0a6c0e0
Autor:
Ilaria Bernabei, Uwe Hansen, Driss Ehirchiou, Jürgen Brinckmann, Veronique Chobaz, Nathalie Busso, Sonia Nasi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9776 (2023)
Pathological cartilage calcification is a hallmark feature of osteoarthritis, a common degenerative joint disease, characterized by cartilage damage, progressively causing pain and loss of movement. The integrin subunit CD11b was shown to play a prot
Externí odkaz:
https://doaj.org/article/70f3bd39567741edbcd2050626fcf013
Autor:
Matthieu Halfon, Li Zhang, Driss Ehirchiou, Vishnuprabu Durairaj Pandian, Suzan Dahdal, Uyen Huynh-Do, Andreas Pasch, Camillo Ribi, Nathalie Busso
Publikováno v:
Genes, Vol 14, Iss 5, p 1105 (2023)
Objectives: CD11B/ITGAM (Integrin Subunit α M) mediates the adhesion of monocytes, macrophages, and granulocytes and promotes the phagocytosis of complement-coated particles. Variants of the ITGAM gene are candidates for genetic susceptibility to sy
Externí odkaz:
https://doaj.org/article/ccf076390b0849bfb6fbd7c72a814329
Autor:
Sonia Nasi, Driss Ehirchiou, Athanasia Chatzianastasiou, Noriyuki Nagahara, Andreas Papapetropoulos, Jessica Bertrand, Giuseppe Cirino, Alexander So, Nathalie Busso
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background Osteoarthritis (OA) is characterized by the formation and deposition of calcium-containing crystals in joint tissues, but the underlying mechanisms are poorly understood. The gasotransmitter hydrogen sulfide (H2S) has been implica
Externí odkaz:
https://doaj.org/article/da06c4deabd248b889dbeec4c5cd2a44
Autor:
Teruo Kusano, Driss Ehirchiou, Tomohiro Matsumura, Veronique Chobaz, Sonia Nasi, Mariela Castelblanco, Alexander So, Christine Lavanchy, Hans Acha-Orbea, Takeshi Nishino, Ken Okamoto, Nathalie Busso
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The roles of the convertible forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO) during tumorigenesis is not known. Here, the authors develop XDH-stable and XO-locked knock-in (ki) mice and show increased tumor growth in XO ki mice, via mac
Externí odkaz:
https://doaj.org/article/a917fab180ef4bcfad65767813174f1d
Autor:
Sonia Nasi, Mariela Castelblanco, Véronique Chobaz, Driss Ehirchiou, Alexander So, Ilaria Bernabei, Teruo Kusano, Takeshi Nishino, Ken Okamoto, Nathalie Busso
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Pathologic calcification of cartilage consists of the formation of basic calcium phosphate (BCP) and/or calcium pyrophosphate dihydrate (CPPD) containing calcium crystals in mature hyaline or articular cartilage and is associated with aging, cartilag
Externí odkaz:
https://doaj.org/article/444fb9d7d56b465aaadd3cc200cd95ae
Autor:
Driss Ehirchiou, Ilaria Bernabei, Véronique Chobaz, Mariela Castelblanco, Thomas Hügle, Alexander So, Li Zhang, Nathalie Busso, Sonia Nasi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Osteoarthritis (OA) is a progressive joint disease that is strongly associated with calcium-containing crystal formation (mineralization) by chondrocytes leading ultimately to cartilage calcification. However, this calcification process is poorly und
Externí odkaz:
https://doaj.org/article/e2d98f68caff45b1bc0c8ddfc33baf15
Autor:
Anajjar Mohamed, Faisal El Mouhafid, Yasser El Brahmi, Mohammed Elfahssi, Mbarek Yakka, Abderrahman Elhjouji, Abdelkader Ehirchiou, Aziz Zentar, Abdelmounaim Ait Ali
Publikováno v:
PAMJ Clinical Medicine, Vol 4, Iss 52 (2020)
Les tumeurs carcinoïdes sont des néoplasmes endocriniens bien différenciés et ne représentent qu´une faible proportion des tumeurs du tube digestif. Le plus souvent asymptomatique, ces tumeurs sont parfois de découverte fortuite en peropérato
Externí odkaz:
https://doaj.org/article/f006ae23d05a423ba85a4af3ba01508e