A perspective from the National Eye Institute Extracellular Vesicle Workshop: Gaps, needs, and opportunities for studies of extracellular vesicles in vision research.

Autor: Lee SY; Department of Ophthalmology, USC Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Klingeborn M; McLaughlin Research Institute, Great Falls, Montana, USA., Bulte JWM; Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Chiu DT; Department of Chemistry and Bioengineering, University of Washington, Seattle, Washington, USA., Chopp M; Department of Neurology, Henry Ford Health, Detroit, Michigan, USA., Cutler CW; Department of Periodontics, Dental College of Georgia at Augusta University, Georgia, USA., Das S; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Egwuagu CE; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA., Fowler CD; Department of Neurobiology and Behavior, University of California Irvine, Irvine, California, USA., Hamm-Alvarez SF; Department of Ophthalmology, USC Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Lee H; Center for System Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Liu Y; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, Georgia, USA., Mead B; School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK., Moore TL; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Ravindran S; Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, Illinois, USA., Shetty AK; Institute for Regenerative Medicine, Department of Cell Biology and Genetics, Texas A&M University School of Medicine, College Station, Texas, USA., Skog J; Exosome Diagnostics, a Bio-Techne Brand, Waltham, Massachusetts, USA., Witwer KW; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Djalilian AR; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA., Weaver AM; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Publikováno v: Journal of extracellular vesicles [J Extracell Vesicles] 2024 Dec; Vol. 13 (12), pp. e70023.

A Camelid-Derived STAT-Specific Nanobody Inhibits Neuroinflammation and Ameliorates Experimental Autoimmune Encephalomyelitis (EAE).

Autor: Mbanefo EC; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Seifert A; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Yadav MK; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Yu CR; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Nagarajan V; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD 20892, USA., Parihar A; Singh Biotechnology, 1547 Fox Grape Loop, Lutz, FL 33558, USA., Singh S; Singh Biotechnology, 1547 Fox Grape Loop, Lutz, FL 33558, USA., Egwuagu CE; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

Publikováno v: Cells [Cells] 2024 Jun 16; Vol. 13 (12). Date of Electronic Publication: 2024 Jun 16.

IL-27-containing exosomes secreted by innate B-1a cells suppress and ameliorate uveitis.

Autor: Kang M; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Yadav MK; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Mbanefo EC; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Yu CR; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Egwuagu CE; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Jun 02; Vol. 14, pp. 1071162. Date of Electronic Publication: 2023 Jun 02 (Print Publication: 2023).

miR-204-containing exosomes ameliorate GVHD-associated dry eye disease.

Autor: Zhou T; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., He C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Lai P; Guangzhou Institutes of Biomedicine and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Guangzhou 510530, P. R. China.; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, P. R. China., Yang Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Liu Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Xu H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Lin X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Ni B; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Ju R; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Yi W; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Liang L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China., Pei D; Guangzhou Institutes of Biomedicine and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Guangzhou 510530, P. R. China., Egwuagu CE; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, USA., Liu X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, P. R. China.

Publikováno v: Science advances [Sci Adv] 2022 Jan 14; Vol. 8 (2), pp. eabj9617. Date of Electronic Publication: 2022 Jan 12.

STAT3-Specific Single Domain Nanobody Inhibits Expansion of Pathogenic Th17 Responses and Suppresses Uveitis in Mice.

Autor: Mbanefo EC; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Yan M; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Kang M; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Alhakeem SA; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Jittayasothorn Y; Immunoregulation Section, Laboratory of Immunology, NEI, NIH, Bethesda, MD, United States., Yu CR; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States., Parihar A; Singh Biotechnology, Tampa Bay, FL, United States., Singh S; Singh Biotechnology, Tampa Bay, FL, United States., Egwuagu CE; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Sep 15; Vol. 12, pp. 724609. Date of Electronic Publication: 2021 Sep 15 (Print Publication: 2021).