Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Egon Werle"'
Publikováno v:
Transfusion Medicine and Hemotherapy. 46:423-430
Background: Daratumumab (DARA), an IgG1κ human monoclonal anti-CD38 antibody, is used for the treatment of refractory myeloma for example. Binding of DARA to CD38 on red blood cells (RBCs), however, leads to panagglutination in indirect antiglobulin
Autor:
Jörg Kreuzer, Egon Werle, Lutz Edler, Konstantinos Cafaltzis, Falk Röder, Ralf Kinscherf, Raoul Breitkreutz, Jürgen Metz, Wulf Hildebrandt, Hans-Peter Deigner, Wulf Dröge, Giso Feussner, Gerd Michel
Publikováno v:
Free Radical Biology and Medicine. 35:1286-1292
Treatment of hyperlipidemic patients with the thiol compound N-acetylcysteine (NAC) was previously shown to cause a significant dose-related increase in the high-density lipoprotein (HDL)-cholesterol serum level, suggesting the possibility that its d
Autor:
Florian Buggle, Egon Werle, Armin J. Grau, Caspar Grond-Ginsbach, Andreas Reis, Heiko Becher, M. Bertram, Athal Al-Khalaf, Natascha Valois
Publikováno v:
Journal of the Neurological Sciences. 192:41-47
Activated monocytes may contribute to the pathogenesis of ischemic stroke. We tested the hypothesis that release products and procoagulant activity of monocytes are increased in acute ischemic stroke. In patients on days 1, 3 and 7 after ischemic str
Publikováno v:
Journal of Cardiovascular Pharmacology. 37:489-492
Asymmetrical dimethyl-L-arginine (ADMA) is an endogenous inhibitor of nitric oxide synthase. We hypothesized that plasma levels of ADMA could be increased in patients with congenital heart disease and pulmonary hypertension. Cardiac catheterization w
Publikováno v:
Movement Disorders. 16:131-134
Iron may play an important role in the pathogenesis of Parkinson's disease (PD). Recent studies have shown that the iron-transporting glycoprotein lactoferrin (LF) and its receptor are increased in the substantia nigra (SN) in PD. We investigated whe
Autor:
Mari Blomberg, Nobuo Ida, Benita Engvall, Johannes Schröder, Malene Jensen, Tobias Hartmann, Konrad Beyreuther, Egon Werle, Lars Lannfelt, Johannes Pantel, M. Jauss, Lars-Olof Wahlund, Hans Basun
Publikováno v:
Annals of Neurology. 45:504-511
All mutations known to cause familial Alzheimer's disease (AD) act by increasing the levels of soluble beta-amyloid peptide (A beta), especially the longer form, A beta42. However, in vivo elevation of soluble A beta in sporadic AD has so far not bee
Publikováno v:
Diabetes Care. 21:994-998
OBJECTIVE To examine the association of renal function in diabetic patients with apolipoprotein (apo) E polymorphism. RESEARCH DESIGN AND METHODS Apo E genotypes, lipid and lipoprotein serum levels, creatinine clearance (CCr), and excretion of marker
Publikováno v:
Environmental Health Perspectives
A cross-sectional study was performed to examine the internal exposure of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDF) in former workers in a nonferrous metal recycling facility. Liver enzymes, lipid parameters, and thyr
Autor:
Hartmut Hengel, Armin J. Grau, E. Zimmermann, Werner Hacke, M. Zorn, M. Spiel, T. Fent, Matthias Maiwald, Florian Buggle, Egon Werle, Heiko Becher
Publikováno v:
Neurology. 50:196-203
We performed a case-control study to investigate the role of recent infection as stroke risk factor and to identify pathogenetic pathways linking infection and stroke. We examined 166 consecutive patients with acute cerebrovascular ischemia and 166 p
Publikováno v:
Metabolism. 47:63-69
the glycoprotein laminin, a cross-shaped complex of three genetically different polypeptide chains, is a structural component of the capillary basement membrane. Serum laminin concentrations of healthy controls (n = 60) and adult type I diabetic pati