5-HT2b receptor antagonist, blocks mCPP-evoked plasma protei•n extravasat1•on in dura mater and capsaicin-evoked c-fos expression 1• n trigeminal nucleus caudalis of rat

Autor: Bonhaus, D. W., Chang, L. K., Cao, Z., Wong, L., Pulido-Rios, T., Webber, A., Leung, E., Flippin, L. A., Eglen, R. M., Martin, G. R.

Publikováno v: Cluster Headache and Related Conditions.

Externí odkaz: https://doi.org/10.1093/oso/9780192630735.003.0047

ST-2560, a selective inhibitor of the Na V 1.7 sodium channel, affects nocifensive and cardiovascular reflexes in non-human primates.

Autor: Mulcahy JV; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Beckley JT; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Klas SD; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Odink DA; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Delwig A; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Pajouhesh H; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Monteleone D; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Zhou X; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Du Bois J; Department of Chemistry, Stanford University, Stanford, California, USA., Yeomans DC; Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Stanford, California, USA., Luu G; SiteOne Therapeutics, Inc., South San Francisco, California, USA., Hunter JC; SiteOne Therapeutics, Inc., South San Francisco, California, USA.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Sep; Vol. 181 (17), pp. 3160-3171. Date of Electronic Publication: 2024 May 07.

Quantitative autoradiography: a tool to visualize and quantify receptors, enzymes, transporters, and second messenger systems

Autor: Sharif, N. A., Eglen, R. M.

Publikováno v: Molecular Imaging in Neuroscience: A Practical Approach.

Externí odkaz: https://doi.org/10.1093/oso/9780199633814.003.0004

Pharmacological characterization of muscarinic receptors in dog isolated ciliary and urinary bladder smooth muscle

Autor: Choppin, A, Eglen, R M

1. The pharmacological characteristics of muscarinic receptors mediating contraction of dog isolated ciliary muscle were determined and compared to those mediating contraction of dog urinary bladder smooth muscle. 2. (+)-Cis-dioxolane induced concent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c0cd3ad4f4a82205c3d38da078adf9d3
https://europepmc.org/articles/PMC1572633/

Characterization of α2-adrenoceptors mediating contraction of dog saphenous vein: identity with the human α2A subtype

Autor: MacLennan, S J, Luong, L A, Jasper, J R, To, Z P, Eglen, R M

1. In the dog saphenous vein alpha 1- and alpha 2-adrenoceptors mediate noradrenaline-induced contractions in vitro. In order to study the alpha 2-adrenoceptor in isolation, alpha 1-adrenoceptors were inactivated by treatment of tissues with the alky

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94f606c48497d845c97bd4d24d213d0b
https://europepmc.org/articles/PMC1564855/