Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eglė A. Ortega"'
Publikováno v:
Biology of Reproduction. 100:810-823
We previously demonstrated that in the mouse only two Y chromosome genes are required for a male to produce an offspring with the help of assisted reproduction technologies (ART): testis determinant Sry and spermatogonial proliferation factor Eif2s3y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca8e3a2372e384c52bd3eed6e47c1e1
https://doi.org/10.1093/biolre/ioy218
https://doi.org/10.1093/biolre/ioy218
Autor:
Quinci Salvador, Eglė A. Ortega, Victor A. Ruthig, Torbjoern Nielsen, Yasuhiro Yamauchi, Monika A. Ward, Jonathan M. Riel
Publikováno v:
Biology of Reproduction. 96:694-706
We recently investigated mice with Y chromosome gene contribution limited to two, one, or no Y chromosome genes in respect to their ability to produce haploid round spermatids and live offspring following round spermatid injection. Here we explored t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f6af178d7d4d3337da487ad777fa98
https://doi.org/10.1095/biolreprod.116.144006
https://doi.org/10.1095/biolreprod.116.144006
Autor:
Victor A. Ruthig, Yasuhiro Yamauchi, Michael J. Mitchell, Eglė A. Ortega, Monika A. Ward, Jonathan M. Riel
Publikováno v:
Science
Science, 2016, 351 (6272), pp.514-516. ⟨10.1126/science.aad1795⟩
Science, American Association for the Advancement of Science, 2016, 351 (6272), pp.514-516. ⟨10.1126/science.aad1795⟩
Science, 2016, 351 (6272), pp.514-516. ⟨10.1126/science.aad1795⟩
Science, American Association for the Advancement of Science, 2016, 351 (6272), pp.514-516. ⟨10.1126/science.aad1795⟩
Replacing the Y chromosome The mammalian Y chromosome encodes a specialized set of genes that are essential for male viability and fertility. In particular, the sex-determining region Y (SRY) protein is necessary to initiate male sex determination. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad34915f769ad28ae2dc36a408c9c1f
https://doi.org/10.1126/science.aad1795
https://doi.org/10.1126/science.aad1795
Publikováno v:
Biology of Reproduction. 93
The Y chromosome gene Sry is responsible for sex determination in mammals and initiates a cascade of events that direct differentiation of bipotential genital ridges toward male-specific fate. Sox9 is an autosomal gene and a primary downstream target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b50c605ba9193cdc82d32cbc33474a86
https://doi.org/10.1095/biolreprod.115.135400
https://doi.org/10.1095/biolreprod.115.135400