Alterations of sex determination pathways in the genital ridges of males with limited Y chromosome genes†

Autor: Monika A. Ward, Mayumi Fernandez, Eglė A. Ortega, Quinci Salvador

Publikováno v: Biology of Reproduction. 100:810-823

We previously demonstrated that in the mouse only two Y chromosome genes are required for a male to produce an offspring with the help of assisted reproduction technologies (ART): testis determinant Sry and spermatogonial proliferation factor Eif2s3y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca8e3a2372e384c52bd3eed6e47c1e1
https://doi.org/10.1093/biolre/ioy218

Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction

Autor: Victor A. Ruthig, Yasuhiro Yamauchi, Michael J. Mitchell, Eglė A. Ortega, Monika A. Ward, Jonathan M. Riel

Publikováno v: Science
Science, 2016, 351 (6272), pp.514-516. ⟨10.1126/science.aad1795⟩
Science, American Association for the Advancement of Science, 2016, 351 (6272), pp.514-516. ⟨10.1126/science.aad1795⟩

Replacing the Y chromosome The mammalian Y chromosome encodes a specialized set of genes that are essential for male viability and fertility. In particular, the sex-determining region Y (SRY) protein is necessary to initiate male sex determination. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad34915f769ad28ae2dc36a408c9c1f
https://doi.org/10.1126/science.aad1795

Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection.

Autor: Tubo, Noah J.¹, Fife, Brian T.², Pagan, Antonio J.³, Kotov, Dmitri I.⁴, Goldberg, Michael F.⁴, Jenkins, Marc K.⁴ jenki002@umn.edu

Publikováno v: Science. 1/29/2016, Vol. 351 Issue 6272, p511-514. 4p.