Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Egil Kvam"'
Publikováno v:
Cancer Letters. 267:18-25
7,8-dihydro-8-oxo-guanine (8-oxoG) is a mutagenic DNA lesion that is induced by ultraviolet A (UVA) radiation. 8-oxoG results in increased frequency of GC-->TA transversion mutations. UVA-induced mutant frequency was measured in the guanine phosphori
Autor:
Egil Kvam, Jostein Dahle
Publikováno v:
Cancer Letters. 221:131-134
Pheomelanin and pheomelanin precursors have been implicated as risk factors for induction of melanoma by ultraviolet radiation. The pheomelanin precursor, 5-S-cysteinyldopa, has been shown to sensitise DNA to oxidative damage by ultraviolet radiation
Publikováno v:
Radiation Research. 163:289-295
Ultraviolet irradiation of cells can induce a state of genomic instability that can persist for several cell generations after irradiation. However, questions regarding the time course of formation, relative abundance for different types of ultraviol
Publikováno v:
Free Radical Biology and Medicine. 28:1191-1196
Heme oxygenase (HO) breaks down heme to iron, biliverdin, and carbon monoxide, and activity of this enzyme increases in many tissues and cell types after exposure to oxidative stress. There is evidence that increased HO activity is involved in long-t
Autor:
Egil Kvam, Rex M. Tyrrell
Publikováno v:
Journal of Investigative Dermatology. 113(2):209-213
Highly pigmented, dark skin is more resistant to the harmful effects of solar ultraviolet radiation than light-colored human skin. The extent to which tanning protects skin from harmful effects including induction of skin cancer is not known, however
Publikováno v:
Human & Experimental Toxicology. 18:495-539
Autor:
Egil Kvam, Trond Stokke
Publikováno v:
Photochemistry and Photobiology. 59:437-440
Human REH cells were incubated with the photosensitizers meso-tetra(4-sulfonatophenyl)porphyrin (TSPP = TPPS4) or meso-tetra(3-hydroxyphenyl)porphyrin (3-THPP). The relatively hydrophilic TSPP was partly found in the cytoplasm and partly in the nucle
Publikováno v:
Nucleic Acids Research. 20:6687-6693
We have exploited properties of photosensitizers to study an aspect of the packing of chromatin in the cell nucleus. The fluorescent photosensitizers mesotetra(3-hydroxyphenyl) porphyrin and Photofrin II were both localized in the nuclear membrane an
Autor:
Jostein Dahle, Egil Kvam
Publikováno v:
Pigment cell research. 17(5)
Publikováno v:
Photochemistry and Photobiology.