Morphological, cellular, and molecular basis of brain infection in COVID-19 patients

Autor: Fernanda Crunfli, Victor C. Carregari, Flavio P. Veras, Lucas S. Silva, Mateus Henrique Nogueira, André Saraiva Leão Marcelo Antunes, Pedro Henrique Vendramini, Aline Gazzola Fragnani Valença, Caroline Brandão-Teles, Giuliana da Silva Zuccoli, Guilherme Reis-de-Oliveira, Lícia C. Silva-Costa, Verônica Monteiro Saia-Cereda, Bradley J. Smith, Ana Campos Codo, Gabriela F de Souza, Stéfanie P. Muraro, Pierina Lorencini Parise, Daniel A. Toledo-Teixeira, Ícaro Maia Santos de Castro, Bruno Marcel Melo, Glaucia M. Almeida, Egidi Mayara Silva Firmino, Isadora Marques Paiva, Bruna Manuella Souza Silva, Rafaela Mano Guimarães, Niele D. Mendes, Raíssa L. Ludwig, Gabriel P. Ruiz, Thiago L. Knittel, Gustavo G. Davanzo, Jaqueline Aline Gerhardt, Patrícia Brito Rodrigues, Julia Forato, Mariene Ribeiro Amorim, Natália S. Brunetti, Matheus Cavalheiro Martini, Maíra Nilson Benatti, Sabrina S. Batah, Li Siyuan, Rafael B. João, Ítalo K. Aventurato, Mariana Rabelo de Brito, Maria J. Mendes, Beatriz A. da Costa, Marina K. M. Alvim, José Roberto da Silva Júnior, Lívia L. Damião, Iêda Maria P. de Sousa, Elessandra D. da Rocha, Solange M. Gonçalves, Luiz H. Lopes da Silva, Vanessa Bettini, Brunno M. Campos, Guilherme Ludwig, Lucas Alves Tavares, Marjorie Cornejo Pontelli, Rosa Maria Mendes Viana, Ronaldo B. Martins, Andre Schwambach Vieira, José Carlos Alves-Filho, Eurico Arruda, Guilherme Gozzoli Podolsky-Gondim, Marcelo Volpon Santos, Luciano Neder, André Damasio, Stevens Rehen, Marco Aurélio Ramirez Vinolo, Carolina Demarchi Munhoz, Paulo Louzada-Junior, Renê Donizeti Oliveira, Fernando Q. Cunha, Helder I. Nakaya, Thais Mauad, Amaro Nunes Duarte-Neto, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Paulo Hilario Nascimento Saldiva, Alessandro S. Farias, Fernando Cendes, Pedro Manoel M. Moraes-Vieira, Alexandre T. Fabro, Adriano Sebollela, José L. Proença-Modena, Clarissa L. Yasuda, Marcelo A. Mori, Thiago M. Cunha, Daniel Martins-de-Souza

Publikováno v: Proceedings of the National Academy of Sciences. 119

Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently characterized as part of “long COVID-19” syndrome) has been frequently observ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47ddeff3c7b9a059a857e00fd4d3c15
https://doi.org/10.1073/pnas.2200960119

SARS-CoV-2 infects brain astrocytes of COVID-19 patients and impairs neuronal viability

Autor: Bruna Manuella Souza Silva, Jaqueline Aline Gerhardt, Iêda Maria Pereira de Sousa, Aline Gazzola Fragnani Valenca, Alessandro S. Farias, M. C. Martini, Maria Ercilia de Paula Castilho Stefano, Vanessa Bettini, Eurico de Arruda Neto, Marjorie Cornejo Pontelli, Paulo Louzada-Junior, Amaro Nunes Duarte-Neto, Guilherme Podolski-Gondim, Bradley J. Smith, Clarissa L. Yasuda, Marina K. M. Alvim, Solange Maria Gonçalves, Marcelo A. Mori, Thais Mauad, Raissa G. Ludwig, Mateus Henrique Nogueira, Elessandra Dias da Rocha, Natália Brunetti Silva, Isadora Marques Paiva, Daniel A. Toledo-Teixeira, André Schwambach Vieira, Ana Campos Codo, Patrícia Brito Rodrigues, Lucas Alves Tavares, José Roberto da Silva Junior, Adriano Sebollela, Fernando Q. Cunha, Niele D. Mendes, Guilherme Ludwig, Gustavo Gastão Davanzo, Stevens K. Rehen, André Saraiva Leão Marcelo Antunes, Glaucia M. Almeida, Verônica M. Saia-Cereda, Daniel Martins-de-Souza, Julia Forato, Lucas Scardua Silva, Egidi Mayara Silva Firmino, Stéfanie Primon Muraro, Bruno Marcel Silva de Melo, Rosa Maria Mendes Viana, Ronaldo B. Martins, Marco Aurélio Ramirez Vinolo, Pedro M. Moraes-Vieira, Ícaro Maia Santos de Castro, Carolina Brandao-Teles, Helder I. Nakaya, Guilherme Reis-de-Oliveira, Lívia Liviane Damião, ítalo Karmann Aventurato, Li Siyuan, Fernando Cendes, Marcelo Volpon Santos, Pierina Lorencini Parise, Carolina Demarchi Munhoz, Pedro Henrique Vendramini, Mariana Rabelo de Brito, Sabrina Setembre Batah, José C. Alves-Filho, Fernanda Crunfli, Gabriel Palermo Ruiz, Victor Corasolla Carregari, Giuliana S. Zuccoli, Flávio P. Veras, Paulo Hilário Nascimento Saldiva, Licia C. Silva-Costa, Maira N. Benatti, Luiz Henrique Lopes da Silva, Gabriela Fabiano de Souza, Rafaela M. Guimarães, Brunno Machado de Campos, Rafael Batista João, Thiago M. Cunha, Luiz Fernando Ferraz da Silva, Thiago L. Knittel, Luciano Neder, José Luiz Proença Modena, André Damasio, Marisa Dolhnikoff, Renê Donizeti Ribeiro de Oliveira, Alexandre Todorovic Fabro, Mariene R. Amorim

COVID-19 patients may exhibit neuropsychiatric and neurological symptoms. We found that anxiety and cognitive impairment are manifested by 28-56% of SARS-CoV-2-infected individuals with mild respiratory symptoms and are associated with altered cerebr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::735d528fb70ac15463da1a095d30ab2c
https://doi.org/10.21203/rs.3.rs-104944/v1

Effect of chronic stress on cardiovascular and ventilatory responses activated by both chemoreflex and baroreflex in rats

Autor: Leonardo B.M. Resstel, Egidi Mayara Silva Firmino, Daniel Penteado Martins Dias, Davi Campos Lagatta, Luciana Bärg Kuntze

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Chronic stress results in physiological and somatic changes. It has been recognized as a risk factor for several cardiovascular dysfunctions and changes in autonomic mechanisms, such as baroreflex and chemoreflex activity. However, the effects of dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4e74630d0a28baa13e1362bd86201e
https://pubmed.ncbi.nlm.nih.gov/31558591

Dorsal hippocampus cholinergic and nitrergic neurotransmission modulates the cardiac baroreflex function in rats.

Autor: Ferreira‐Junior, Nilson Carlos¹ (AUTHOR), Lagatta, Davi Campos¹ (AUTHOR), Kuntze, Luciana Bärg¹ (AUTHOR), Fujiwara, Eduardo Akira² (AUTHOR), Firmino, Egidi Mayara Silva¹ (AUTHOR), Borges‐Assis, Anna Bárbara¹ (AUTHOR), Resstel, Leonardo Barbosa Moraes¹ (AUTHOR) leoresstel@fmrp.usp.br, Sampaio, Karla Nívea² (AUTHOR)

Publikováno v: European Journal of Neuroscience. Feb2020, Vol. 51 Issue 4, p991-1010. 20p. 2 Diagrams, 3 Charts, 7 Graphs.