Organ-Specific Immune Setpoints Underlie Divergent Immune Profiles across Metastatic Sites in Breast Cancer.

Autor: Egelston CA; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Guo W; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Simons DL; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Ye J; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Avalos C; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Solomon ST; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Nwangwu M; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Nelson MS; The Light Microscopy and Digital Imaging Core, Beckman Research Institute, City of Hope, Duarte, California., Tan J; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California., Bacon ER; Department of Medical Oncology, City of Hope, Duarte, California., Ihle K; Department of Medical Oncology, City of Hope, Duarte, California., Schmolze D; Department of Pathology, City of Hope, Duarte, California., Tumyan L; Department of Diagnostic Radiology, City of Hope, Duarte, California., Waisman JR; Department of Medical Oncology, City of Hope, Duarte, California., Lee PP; Department of Immuno-Oncology, Beckman Research Institute, City of Hope, Duarte, California.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 Nov 04; Vol. 12 (11), pp. 1559-1573.

Tumor heterogeneity and clinically invisible micrometastases in metastatic breast cancer-a call for enhanced surveillance strategies.

Autor: Bacon ER; The Center for Precision Medicine, City of Hope National Medical Center, Duarte, CA, USA. ebarragan@coh.org.; Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA. ebarragan@coh.org., Ihle K; The Center for Precision Medicine, City of Hope National Medical Center, Duarte, CA, USA.; Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA., Guo W; Department of Immuno-Oncology, Beckman Research Institute at City of Hope, Duarte, CA, USA., Egelston CA; Department of Immuno-Oncology, Beckman Research Institute at City of Hope, Duarte, CA, USA., Simons DL; Department of Immuno-Oncology, Beckman Research Institute at City of Hope, Duarte, CA, USA., Wei C; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA., Tumyan L; Diagnostic Radiology, City of Hope National Medical Center, Duarte, CA, 91010, USA., Schmolze D; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA., Lee PP; Department of Immuno-Oncology, Beckman Research Institute at City of Hope, Duarte, CA, USA., Waisman JR; Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.

Publikováno v: NPJ precision oncology [NPJ Precis Oncol] 2024 Mar 29; Vol. 8 (1), pp. 81. Date of Electronic Publication: 2024 Mar 29.

Peritumoral Immune-suppressive Mechanisms Impede Intratumoral Lymphocyte Infiltration into Colorectal Cancer Liver versus Lung Metastases.

Autor: Ye J; Department of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, California., Guo W; Department of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, California., Wang C; Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, California., Egelston CA; Department of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, California., D'Apuzzo M; Department of Pathology, City of Hope National Medical Center, Duarte, California., Shankar G; College of Medicine, University of Cincinnati, Cincinnati, Ohio., Fakih MG; Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, California., Lee PP; Department of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, California.

Publikováno v: Cancer research communications [Cancer Res Commun] 2023 Oct 12; Vol. 3 (10), pp. 2082-2095.

Genomic Markers of CDK 4/6 Inhibitor Resistance in Hormone Receptor Positive Metastatic Breast Cancer.

Autor: Lee JS; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Yost SE; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Li SM; Department of Biostatistics, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Cui Y; Department of Biostatistics, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Frankel PH; Department of Biostatistics, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Yuan YC; Department of Computational Quantitative Medicine, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Schmolze D; Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Egelston CA; Department of Immuno-Oncology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Guo W; Department of Immuno-Oncology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Murga M; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Chang H; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Bosserman L; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA., Yuan Y; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.

Publikováno v: Cancers [Cancers (Basel)] 2022 Jun 28; Vol. 14 (13). Date of Electronic Publication: 2022 Jun 28.

Phase I/II trial of palbociclib, pembrolizumab and letrozole in patients with hormone receptor-positive metastatic breast cancer.

Autor: Yuan Y; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA. Electronic address: yuyuan@coh.org., Lee JS; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Yost SE; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Frankel PH; Department of Biostatistics, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Ruel C; Department of Biostatistics, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Egelston CA; Department of Immune-Oncology, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Guo W; Department of Immune-Oncology, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Padam S; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Tang A; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Martinez N; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Schmolze D; Department of Pathology, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Presant C; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Ebrahimi B; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Yeon C; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Sedrak M; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Patel N; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Portnow J; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Lee P; Department of Immune-Oncology, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA., Mortimer J; Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Beckman Research Institute, Duarte, CA, USA.

Publikováno v: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2021 Sep; Vol. 154, pp. 11-20. Date of Electronic Publication: 2021 Jul 01.