Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ege, Arzuk"'
Autor:
Emre Ozgenc, Merve Karpuz, Ege Arzuk, Marta Gonzalez-Alvarez, Marival Bermejo Sanz, Evren Gundogdu, Isabel Gonzalez-Alvarez
Publikováno v:
ACS Omega. 7:30015-30027
Radiolabeled trastuzumab (TRZ) loaded solid lipid nano-particles (SLNs) were prepared by high shear homogenization and sonication techniques. The apoptosis mechanism of TRZ-SLNs was studied only with the MCF-7 cell line, while the cytotoxicity and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32417c74583436aa9232279fb036471
https://doi.org/10.1021/acsomega.2c03023
https://doi.org/10.1021/acsomega.2c03023
Publikováno v:
Toxicology Letters. 363:36-44
Mitochondria appeared to be a major target for paracetamol (PAR)-induced hepatotoxicity. Studies suggested that microsomal CYPs catalyse bioactivation of PAR to N-acetyl-p-benzoquinone imine (NAPQI), which alkylates mitochondrial proteins, and causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a773015bbd6cb09994fa2920386d197
https://doi.org/10.1016/j.toxlet.2022.05.005
https://doi.org/10.1016/j.toxlet.2022.05.005
Publikováno v:
Endocrine, Metabolic & Immune Disorders - Drug Targets. 23
Aim: To provide in vitro data on toxicity mechanisms of clozapine, diclofenac and nifedipine. Background: CHO-K1 cells were used as in vitro model to explore mechanisms of cytotoxicity of the test drugs. Objective: Cytotoxic mechanisms of clozapine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed0f8b2da53c93c0f2b0e8970b03cfa9
https://doi.org/10.2174/1871530323666230419084613
https://doi.org/10.2174/1871530323666230419084613
Publikováno v:
Toxicology for the Health and Pharmaceutical Sciences ISBN: 9780203730584
Toxicology for the Health and Pharmaceutical Sciences
Toxicology for the Health and Pharmaceutical Sciences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd4757a6ffeb2d334bae3eafa6f76b2
https://doi.org/10.1201/9780203730584-12
https://doi.org/10.1201/9780203730584-12
Publikováno v:
Toxicology. 447:152628
The mechanism of clozapine-associated cardiotoxicity has not been elucidated. The formation of a reactive nitrenium ion from the drug has been suggested as the cause, however, the reason why the heart is a target remains unknown. The heart is one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52163c71f852b209cbef7521894ecd8b
https://doi.org/10.1016/j.tox.2020.152628
https://doi.org/10.1016/j.tox.2020.152628
Paracetamol (PAR) overdose is associated with massive hepatic injury; it may induce kidney toxicity as well. It is essential to measure organ-specific activities of related CYPs for evaluating the overdose cases. Available HPLC-based methods require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c5bb6bfe8a5900594ba27afbe9235e
https://aperta.ulakbim.gov.tr/record/30595
https://aperta.ulakbim.gov.tr/record/30595
Autor:
Regina M. Santella, Andrea Rossnerova, Neliye Mutlu, Marcus S. Cooke, Antonin Ambroz, Gudrun Koppen, Pavel Rossner, Jiri Neca, Kazuo Sakai, Radim J. Sram, Miroslav Ciganek, Ege Arzuk, Hilmi Orhan
ELISA is commonly used for the detection of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a marker of whole body oxidative stress. However, the method has been criticized for high inter-laboratory variability and poor agreement with chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a699d81742846a3930fee0005d7f154
https://aperta.ulakbim.gov.tr/record/53611
https://aperta.ulakbim.gov.tr/record/53611
Publikováno v:
Toxicology Letters. 258:S305
Öz bulunamadı.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd48fb12abba65e52759aea1e1b73f79
https://doi.org/10.1016/j.toxlet.2016.06.2044
https://doi.org/10.1016/j.toxlet.2016.06.2044
Publikováno v:
Toxicology Letters. 238:S314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c255e31e35ac65667d089fa2f7e4bd
https://doi.org/10.1016/j.toxlet.2015.08.897
https://doi.org/10.1016/j.toxlet.2015.08.897
Publikováno v:
Toxicology Letters. 221:S179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae2d803a5da4ff51f376c171d9f34f4b
https://doi.org/10.1016/j.toxlet.2013.05.399
https://doi.org/10.1016/j.toxlet.2013.05.399